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Protein–lipid charge interactions control the folding of outer membrane proteins into asymmetric membranes
Biological membranes consist of two leaflets of phospholipid molecules that form a bilayer, each leaflet comprising a distinct lipid composition....
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Bacterial outer membrane vesicle-cancer cell hybrid membrane-coated nanoparticles for sonodynamic therapy in the treatment of breast cancer bone metastasis
Breast cancer bone metastasis is a terminal-stage disease and is typically treated with radiotherapy and chemotherapy, which causes severe side...
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Predicting permeation of compounds across the outer membrane of P. aeruginosa using molecular descriptors
The ability Gram-negative pathogens have at adapting and protecting themselves against antibiotics has increasingly become a public health threat....
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Outer membrane vesicles generated by an exogenous bacteriophage lysin and protection against Acinetobacter baumannii infection
BackgroundThe outer membrane vesicles (OMVs) produced by Gram-negative bacteria can modulate the immune system and have great potentials for...
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Extraction of the outer membrane protein pertactin from Bordetella pertussis with urea for the production of acellular pertussis vaccine
Pertactin (PRN), a non-fimbrial outer membrane protein of Bordetella pertussis , is the limiting component of the acellular pertussis vaccine because...
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Isolation and characterization of a main porin from the outer membrane of Salinibacter ruber
Salinibacter ruber is an extremophilic bacterium able to grow in high-salts environments, such as saltern crystallizer ponds. This halophilic...
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Surface Plasmon Resonance (SPR) Biosensor for the Detection of SARS-CoV-2 Using Autodisplyaed FV-antibodies on Outer Membrane of E. coli
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleocapsid protein (NP) participates in viral genome packaging and abundantly...
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Serodiagnosis of human brucellosis by an indirect ELISA test using recombinant outer membrane protein 19 kDa (rOMP19) as an antigen
BackgroundBrucellosis remains one of the global health concerns that reemerges in recent years. Delayed or inaccurate diagnosis end to a long...
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Differential reinforcement of cGAS-STING pathway-involved immunotherapy by biomineralized bacterial outer membrane-sensitized EBRT and RNT
Radiotherapy (RT), including external beam radiation therapy (EBRT) and radionuclide therapy (RNT), realizes physical killing of local tumors and...
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In Silico Design of CT26 Polytope and its Surface Display by ClearColi™-Derived Outer Membrane Vesicles as a Cancer Vaccine Candidate Against Colon Carcinoma
Simultaneous targeting of several mutations can be useful in colorectal cancer (CRC) due to its heterogeneity and presence of somatic mutations. As...
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Outer-surface Covering of Nanochannels with Hydrogel for Highly Sensitive and Specific Cr(VI) Detection Through Analyte-caused Charge Change in Hydrogel
Nanochannels have made great progress and are a promising platform for detecting a series of targets. However, most nanochannels are modified on the...
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Outer Membrane Vesicles (OMVs) as a Platform for Vaccination and Targeted Drug Delivery
Outer membrane vesicles (OMVs) are nanoparticles secreted from the bacterial cell surface. They range from 10 to 300 nm in size and possess similar...
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A Study on the Mechanical and Physiological Performance of the Nylon Outer Shell of Extreme Cold Weather Clothing
For the first time, an optimized twill ripstop woven structure having an areal density of 70 g/m 2 has been introduced as an outer shell protective...
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The penetration of human defensin 5 (HD5) through bacterial outer membrane: simulation studies
Human α-defensin 5 (HD5) is one of cationic antimicrobial peptides which plays a crucial role in an innate immune system in human body. HD5 shows the...
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Rational design of dynamic fibre membrane for sustainable biofouling control
Current surface-controlled biofouling-based membrane technologies are retarded by short-run anti-biofouling performances. Dynamic fibre membrane,...
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Transcending membrane barriers: advances in membrane engineering to enhance the production capacity of microbial cell factories
Microbial cell factories serve as pivotal platforms for the production of high-value natural products, which tend to accumulate on the cell membrane...
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Escherichia coli displays a conserved membrane proteomic response to a range of alcohols
BackgroundAlcohol is a good and environment-friendly fuel that can be microbially produced, capable of eliminating many of the limitations of the...
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Effect of spinning parameter on the properties and performance of hollow fiber supported liquid membrane for levulinic acid extraction
A hollow fiber-supported liquid membrane (HFSLM) configuration with a large membrane surface area per volume is becoming more viable and feasible to...
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Insights into the structure of Escherichia coli outer membrane as the target for engineering microbial cell factories
Escherichia coli is generally used as model bacteria to define microbial cell factories for many products and to investigate regulation mechanisms. E....
