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Quantification of Methylation and Phosphorylation Stoichiometry
Tauopathies including Alzheimer’s disease (AD) are neurodegenerative disorders accompanied by the conversion of functional forms of the microtubule...
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Capture Methylation-Sensitive Restriction Enzyme Sequencing (Capture MRE-Seq) for Methylation Analysis of Highly Degraded DNA Samples
Understanding the impact of DNA methylation within different disease contexts often requires accurate assessment of these modifications in a...
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Emerging methylation-based approaches in microbiome engineering
Bacterial epigenetics, particularly through DNA methylation, exerts significant influence over various biological processes such as DNA replication,...
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Catalytic Methylation Using Methanol as C1 Source
The development of 3d metal-catalyzed molecular transformations has been a key focus of research in recent decades. One significant advancement is...
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Correlation of ChREBP Gene Methylation with Pathological Characteristics of Type 2 Diabetes Mellitus
The objective of this study is to investigate the expression of the carbohydrate response element binding protein (ChREBP) gene in type 2 diabetes...
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Traditional Korean diet high in one-carbon nutrients increases global DNA methylation: implication for epigenetic diet
PurposeDNA methylation is a major epigenetic phenomenon through which diet affects health and disease. This study aimed to determine the epigenetic...
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Crosstalk Between m6A RNA Methylation and miRNA Biogenesis in Cancer: An Unholy Nexus
N6-methyladenosine (m6A) is one of the most prevalent internal reversible chemical modification of RNAs in eukaryotes, which has attracted widespread...
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Photoelectrochemical sensor based on AuNPs@WO3@TpPa-1-COF for quantification of DNA methylation levels
A “signal-off” photoelectrochemical (PEC) sensing platform has been designed for the ultrasensitive detection of DNA methylation levels and multiple...
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Methylation enables the use of fluorine-free ether electrolytes in high-voltage lithium metal batteries
Lithium metal batteries represent a promising technology for next-generation energy storage, but they still suffer from poor cycle life due to...
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Folate deficiency modifies the risk of CIN3+ associated with DNA methylation levels: a nested case–control study from the ASCUS-COL trial
PurposeTo our knowledge, there are very few studies evaluating if the levels of folate modify the risk of cervical intraepithelial neoplasia grade 2...
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Hybridization-based CpG methylation level detection using methyl-CpG-binding domain–fused luciferase
Hypermethylation of tumor-suppressor genes and global hypomethylation, which is related to methylation level at the retroelement, have been...
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Ischemic preconditioning modulates the DNA methylation process of the rat heart to provide tolerance to withstand ischemia reperfusion injury and its associated mitochondrial dysfunction
DNA methylation plays a crucial role in the pathogenesis of myocardial ischemia reperfusion injury(I/R) and the I/R injury can be combated...
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Droplet Magnetofluidic Assay Platform for Quantitative Methylation-Specific PCR
Early cancer detection requires identification of cellular changes resulting from oncogenesis. Abnormal DNA methylation patterns occurring early in...
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miR-375 Combined with SHOX2 Methylation has Higher Diagnostic Efficacy for Non-Small-Cell Lung Cancer
Non-small-cell lung cancer (NSCLC) is a high-risk type of lung cancer. This study aims to improve the diagnostic efficacy of NSCLC through the...
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ALS-linked FUS R521C disrupts arginine methylation of UBAP2L and stress granule dynamics
Mutations in the fused-in-sarcoma (FUS) gene have been linked to familial amyotrophic lateral sclerosis (fALS). FUS aggregates in the cytosol and...
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Highly Effective Zirconia/γ-Alumina for Continuous Vapor Phase N-methylation of Aniline
High-surface-area ZrO 2 / γ -Al 2 O 3 catalysts were used for the selective N- methylation of aniline with methanol at mild temperature and atmospheric...
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Identifying a Risk Signature of Methylation-Driven Genes as a Predictor of Survival Outcome for Colon Cancer Patients
Aberrant expression of gene is driven by its promoter methylation and is the key molecular basis of carcinogenic processes. This study aimed at...
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Gas-phase O-methylation of catechol with dimethyl carbonate over SBA-15-supported aluminum phosphate catalyst
SBA-15-supported Al 2 O 3 -P 2 O 5 with 10 wt% Al 2 O 3 and different P 2 O 5 mass percentages (10Al 2 O 3 - x P 2 O 5 /SBA-15) were prepared by simple impregnation method...
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Methylation and Amination of 4H-[1,2,3]Triazolo[4,5-c][1,2,5]oxadiazole Salts
AbstractMethylation and amination reactions of 4 Н -[1,2,3]triazolo[4,5- c ][1,2,5]oxadiazole salts (K + , Ag + , Et 3 NH + , DBUH + ) have been studied for the...
