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Gelation of cytoplasmic expanded CAG RNA repeats suppresses global protein synthesis
RNA molecules with the expanded CAG repeat (eCAGr) may undergo sol–gel phase transitions, but the functional impact of RNA gelation is completely...
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Novel Approaches in Nasal In Situ Gel Drug Delivery
The nasal cavity represents a suitable administration route both for local and systemic treatments. Conventional nasal formulations (liquid, solid,...
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Micellization and gelation characteristics of different blends of pluronic F127/methylcellulose and their use as mucoadhesive in situ gel for periodontitis
Micellization and gelation phenomena of thermosensitive hydrogels based on various concentrations of Pluronic F127 (PF) and 4% w/w methylcellulose...
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Review of Recent Advances in the Use of Drug Delivery Systems in Ophthalmology
AbstractEye drops represent the traditional form of medication delivery for the eyes, constituting approximately 90% of the presently available...
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In situ Forming Hydrogel Crosslinked with Tetronic Micelle for Controlled Delivery of Hydrophobic Anticancer Drug
For cancer treatment, anti-cancer hydrophobic drugs such as paclitaxel (PTX) are usually intravenously administrated as a systemic delivery which has...
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The Impact of Temperature on the Formation, Release Mechanism, and Degradation of PLGA-based In-Situ Forming Implants
This study explores the impact of varying temperatures on the release behavior of Triptorelin Acetate (TA) from a PLGA-based in-situ forming implant...
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Dynamic assembly and biocatalysis-selected gelation endow self-compartmentalized multienzyme superactivity
Cellular metabolism in multiple organelles utilizes compartmentalized multienzyme efficient catalysis to realize substance metabolism, energy...
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A review of solid-state lithium metal batteries through in-situ solidification
High-energy-density lithium metal batteries are the next-generation battery systems of choice, and replacing the flammable liquid electrolyte with a...
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Effect of dispersed phase concentration on gelation and formation of silver nanoparticles in aqueous solutions of l-cysteine and silver nitrite
Self-assembly processes in aqueous solutions of l -cysteine and silver nitrite (AgNO 2 ) with different concentrations and varying molar ratios of the...
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Controlling gelation time of in situ polymerization of gel system through AGET ATRP principle
To better control the gelation time of in situ polymerization of gel system in reservoir, an activator regenerated by AGET (activator generated by...
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Photochemical graft of γ-cyclodextrin’s interior leading to in-situ charge-transfer complexes with unusual regioselectivity and its application in 3D photo-printing
Photoirradiation of anthraquinone (AQ) derivatives with γ-cyclodextrin (γ-CD) in aqueous solution led to a γ-CD derivative with a...
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A Study of Cryostructuring of Polymer Systems. 54. Hybrid Organo-Inorganic Poly(vinyl alcohol) Cryogels Filled with In situ Formed Silica
AbstractMacroporous viscoelastic poly(vinyl alcohol) (PVA) cryogels are formed via the cryogenic processing (freezing/incubation in the frozen...
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Marine biomaterials in biomedical nano/micro-systems
Marine resources in unique marine environments provide abundant, cost-effective natural biomaterials with distinct structures, compositions, and...
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pH-Sensitive poly (acrylic acid-co-acrylamide) anionic hydrogels for jejunum targeted drug delivery systems
Ionic hydrogels are favorable for drug delivery applications, and fluorescence probes have been employed to analyze drug carriers. In this work, we...
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Biopolymer Aerogels as Nasal Drug Delivery Systems
AbstractProtein (eggwhite) and chitosan aerogel microparticles characterized by low density, developed morphology, high specific surface area, high...
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Effect of cellulose nanocrystals on rheology, liquid crystal, and delivery behavior of metronidazole poloxamer-based in-situ dental medication
Poloxamers possess unique gelling properties for use in drug delivery applications; however, their rheological and drug release properties are...
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Recent Advances on the Generation, Stabilization, and Potential Applications of Double Emulsions Based on the Microfluidic Strategy
Double emulsions (DEs) have attracted wide attention because of its excellent encapsulation of hydrophilic and hydrophobic bioactives simultaneously....
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The Effect of Blending Ratio on the Structure and Properties of the PPR/PS In situ Fiber Reinforced System Prepared by Multi-Flow Vibration Injection Molding
To enhance the mechanical properties of polypropylene random copolymer (PPR), polystyrene (PS) with four different contents were added to the PPR...
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In situ forming thermosensitive vaginal hydrogels containing curcumin-loaded polymeric nanoparticles with their sustained release: rheological measurements and cytotoxicity effect on cervix cancer cell
This study developed a novel temperature-sensitive Pluronic F127 (PF127) gel-containing curcumin (CRC)/thiolated chitosan (TC) nanoparticles (NPs)...
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Biomaterials in Drug Delivery Systems
Drug delivery research is advancing day by day due to the advancement of science and technology, which helps cure many diseases. Traditionally, drugs...