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The Search for Domestic Pharmaceutical Substances among Metal Complexes Based on (Hetero)arylamides of 4-Aryl-2-hydroxy-4-oxo-2-butenoic Acids
AbstractThe data obtained on the synthesis and search for biological activity among metal complexes based on 4-aryl-2-hydroxy-4-oxo-2-butenoic acid...
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Metallatranes and hydrometallatranes: their immunotropic and antitumor properties
A series of biologically active metallatranes and hydrometallatranes was synthesized via the reaction of biogenic triethanolamine with salts or...
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Synthesis and antimicrobial activity of silicon—titanium—zinc- and silicon—titanium—boron-containing glycerohydrogels
Novel pharmacologically active silicon—titanium—zinc- and silicon—titanium—boron-containing glycerohydrogels were synthesized by the sol—gel method...
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Various Synthetic Strategies and Therapeutic Potential of Thiadiazole, Oxadiazole, Isoxazole and Isothiazole Derivatives
The five-membered heterocyclic moieties comprising three hetero atoms or two hetero atoms (generally “N” and “S”) have gained significant interest... -
The Influence of Effect of Polysaccharides and Polyvinylpyrrolidone on the Photocatalytic Activity of Chlorin e6 in Tryptophan Oxidation
AbstractThe effect amphiphic polymer poly- N -vinylpyrrolidone (PVP) and polysaccharides (PSs), sodium alginate (SA) and hyaluronic acid (HA), have on...
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Bioactive silicon-iron-containing glycerohydrogel synthesized by the sol—gel method in the presence of chitosan
A novel biologically active nanocomposite glycerohydrogel based on two biocompatible precursors, silicon and iron glycerolates, was synthesized by...
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Contribution of the Scientific School of Academician M.G. Voronkov to the Development of the Chemistry of Biologically Active Atranes (Protatranes and Hydrometallatranes) (A Review)
AbstractThe main results of the many years’ studies of the scientific school of Academician Mikhail G. Voronkov in the field of two subgroups of the...
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Structure and properties of chitosan salt complexes with ascorbic acid diastereomers
The study attests the effect of l - and d -diastereomers of ascorbic acid, which were used to prepare a salt form of chitosan, on the conformational...
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Synthesis and pharmacological activity of a silicon—zinc—boron-containing glycerohydrogel
A new pharmacologically active nanostructured silicon—zinc—boron-containing glycerohydrogel was synthesized by the sol—gel method using silicon,...
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Catalytic Alkylation of Adamantane with Propylene: Quantum-Chemical Calculations and Experimental Data
AbstractThe mechanism of interaction of adamantane with propylene has been studied by quantum-chemical calculations within the density functional...
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Synthesis and Pharmacological Activity of Tris(2-hydroxyethyl)ammonium 4-Chlorophenylsulfonylacetate
Methods for the synthesis of 4-chlorophenylsulfonylacetic acid and its tris (2-hydroxyethyl)ammonium salt (“sulfacetamine”) were studied. The results...
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Mechanisms of Candida Resistance to Antimycotics and Promising Ways to Overcome It: The Role of Probiotics
Pathogenic Candida and infections caused by those species are now considered as a serious threat to public health. The treatment of candidiasis is...
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Synthesis of [1,3]Thiazolo[2,3-i]purinium Systems
The alkylation of purine-6-thiol with methallyl chloride and propargyl bromide in aqueous alcohol in the presence of alkali gave...
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Synthesis of Immunoactive Tris(2-hydroxyethyl)ammonium 1-R-Indol-3-ylsulfanyl(sulfonyl)acetates
Difficultly accessible 1-R-indol-3-ylsulfanyl(sulfonyl)acetic acids 1-R-IndYCH 2 CO 2 H (R = H, Me, Bn; Y = S, SO 2 ) 1a–Id were prepared. Their reaction...
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Fe-containing nanocomposites based on a biocompatible copolymer 1-vinyl-1,2,4-triazole with N-vinylpyrrolidone
New polymer nanocomposites containing iron oxide nanoparticles stabilized with a biocompatible copolymer of 1-vinyl-1,2,4-triazole with N -vinylpyrroli...
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Role of Neurochemicals in the Interaction between the Microbiota and the Immune and the Nervous System of the Host Organism
This work is concerned with the role of evolutionary conserved substances, neurotransmitters, and neurohormones, within the complex framework of the mi...
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Tris(2-hydroxyethyl)ammonium arylchalcogenylacetates, growth stimulants of alcohol yeast Saccharomyces cerevisiae
A number of tris(2-hydroxyethyl)ammonium arylchalcogenylacetates ArYCH 2 CO 2 – • •HN + (CH 2 CH 2 OH) 3 ( 1—4 ) (Ar = aryl; Y = O, S, SO 2 ) were synthesized. Their...
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Synthesis of novel pyrazolyl derivatives of 1,3-diazaadamantane
Pyrazole-containing derivatives of 1,3-diazaadamantane were obtained as a result of condensation of alkyl-substituted...
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Oxidative functionalization of adamantanes (review)
The results of studies in the area of oxidative functionalization of hydrocarbons of the adamantane series over the last two decades have been...