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Polymer-Based Delivery of Peptide Drugs to Treat Diabetes: Normalizing Hyperglycemia and Preventing Diabetic Complications
Diabetes is a serious metabolic disease in which chronic hyperglycemia results in diabetic microvascular and macrovascular complications from...
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7-Ethoxyrosmanol alleviates hyperglycemia-induced vascular endothelial dysfunction by regulating FBXL7 expression
The current therapeutic strategy for hyperglycemia is reasonable diet and appropriate exercise with drugs, whose outcome is unsatisfied. Therefore,...
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Capsicum annuum L. cv. DANGJO ameliorated hyperglycemia in type 2 diabetes animal model induced by high-fat diet and streptozotocin
In this study, it was evaluated the effect of freeze-dried powder of Capsicum annuum L. cv. DANGJO (DJ) on ameliorating hyperglycemia in type 2...
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Clinical Association of Biochemical Variations Among Multilocus Genotypes of Antioxidant Enzymes with Susceptibility of Cataract in Hyperglycemia
Hyperglycemia plays a pronounced role in accelerating the process of aging due to high oxidative stress which triggers dyslipidemia and subsequently...
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Trajectories of energy intake distribution and subsequent risk of hyperglycemia among Chinese adults: findings from the China Health and Nutrition Survey (1997–2018)
AimsFew studies have examined the secular trend of the energy intake distribution, and its effect on future risk of hyperglycemia. This study aims to...
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Amelioration of hyperglycemia and hyperlipidemia in a high-fat diet-fed mice by supplementation of a developed optimized polyherbal formulation
This study evaluated in vivo anti-diabetic and anti-obesity activity of a polyherbal formulation’s methanolic extract containing an optimized ratio...
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Blended extract of oat, sorghum, adzuki bean, finger millet, and proso millet improved hyperglycemia and insulin resistance in the streptozotocin–nicotinamide-induced diabetic rats
Grains contain bioactive components that potentially have protective effects on chronic diseases such as diabetes. The anti-diabetic effects of...
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Production and Internalization of Extracellular Vesicles in Norm and under Conditions of Hyperglycemia and Insulin Resistance
Abstract —Extracellular vesicles (EVs) are spherical functionally important structures of cell membrane origin ranging in size from 40 nm to 5000 nm....
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Gryllus bimaculatus extract ameliorates high-fat diet-induced hyperglycemia and hyperlipidemia by inhibiting hepatic lipogenesis through AMPK activation
Insect-based food is increasingly used and is a sustainable protein source provided by eco-friendly breeding respecting the animal welfare. The...
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Therapeutic effect of curcumin and C60 fullerene against hyperglycemia-mediated tissue damage in diabetic rat lungs
Increasing evidence suggests that diabetes also targets lung tissues resulting in structural and physiological abnormalities. The present study...
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Hyperglycemia-Induced Cardiac Damage Is Alleviated by Heat-Inactivated Lactobacillus reuteri GMNL-263 via Activation of the IGF1R Survival Pathway
AbstractDiabetes-induced cardiomyocyte apoptosis is one of the major causes of mortality in patients with diabetes. Numerous studies have indicated...
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Healthy dietary pattern is associated with lower glycemia independently of the genetic risk of type 2 diabetes: a cross-sectional study in Finnish men
PurposeHyperglycemia is affected by lifestyle and genetic factors. We investigated if dietary patterns associate with glycemia in individuals with...
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Heterocyclic chalcone (E)-1-(2-hydroxy-3,4,6-trimethoxyphenyl)-3-(thiophen-2-yl) prop-2-en-1-one derived from a natural product with antinociceptive, anti-inflammatory, and hypoglycemic effect in adult zebrafish
Diabetes is a disease linked to pathologies, such as chronic inflammation, neuropathy, and pain. The synthesis by the Claisen−Schmidt condensation...
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Polyphenols in foods: a potential strategy for preventing and managing the postprandial hyperglycemic response
Type 2 diabetes mellitus (T2DM) is a significant health risk worldwide, and effective management strategies are needed. Polyphenols exhibit diverse...
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Selenium-Enriched and Ordinary Black Teas Regulate the Metabolism of Glucose and Lipid and Intestinal Flora of Hyperglycemic Mice
Black tea is one of the six major tea categories and has a variety of bioactivities. However, little is known about its comprehensive evaluation of...
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Aberrant PDK4 Promoter Methylation Preceding Hyperglycemia in a Mouse Model
Diabetic prevalence is at speedy increase globally. Previous studies stated that other than genetics, factors such as environment, lifestyle, and...
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Chitosan Based Hybrid Polymeric Systems in Diabetes Monitoring
Diabetes is an endocrinometabolic disorder caused due to the irregular glucose metabolism. Insulin is secreted by pancreatic islets of β-cells....
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Extraction of Sericin from Cocoons of the Silkworm Bombyx Mori, Its Characteristics, and a Dietary Supplement on Its Basis to Prevent Diabetes Mellitus
AbstractA dietary supplement for the prevention of diabetes mellitus was obtained based on sericin separated from the cocoons of the silkworm Bombyx...
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Synthesis, In Vitro α-Amylase Inhibition Activity and Molecular Docking of some Coumarin Derivatives
Coumarins represent a large number of natural and synthetic bioactive molecules. Their oxygen-containing heterocyclic structure makes them...
