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Hydrazone analogs as DNA gyrase inhibitors and antioxidant agents: Structure-activity relationship and pharmacophore modeling
In this paper, we report the synthesis and the structure–activity relationship study of three hydrazone analogs; the Schiff base hydrazone SBH and 2,...
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Exploring two distinct crystallization pathways of pyridinoyl-hydrazone derivatives of isosteviol: true and pseudosymmetric homochiral motifs
The coexistence of two fragments, a chiral isosteviol moiety and an achiral pyridinoyl-hydrazone moiety, in the molecules of pyridinoyl-hydrazone...
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Three Cu (II)-hydrazone complexes: synthesis, physicochemical characteristics, stability, thermal analysis, and investigation of metal and iodine absorption
A three Schiff bases; Lhy, Lme, and Lph, as well as their CuLhy, CuLme, and CuLph complexes, were synthesized, and their physicochemical properties...
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Synthesis, Crystal Structure, Hirshfeld Surface Analysis and Computational Study of Hydrazone Derivative of 5,5-dimethylcyclohexane-1,3-dione
AbstractThe diazotization reaction of p -fluoroaniline from aromatic amines with 5,5-dimethylcyclohexane-1,3-dione was studied, as a result 2-(2-( p -fl...
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A novel chromene acyl hydrazone Schiff base organogel with colorimetric Cu2+ responsive
A novel ionic responsive Schiff base organic gelator was successfully designed and synthesized. The solvent selection experiment showed that the...
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Synthesis of New Hydrazone Compounds from Natural Grease and Investigation as Flow Improver for Crude Oil
AbstractIn this work, salicylaldehyde hydrazone (SAH), different from the traditional polymers, was synthesized from natural oils (castor, SA С H,...
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Synthesis, characterization and sensor properties of a new sulfonyl hydrazone derivative molecule: potentiometric determination of Pb(II) ions
In this study, a new sulfonyl hydrazone derivative molecule was synthesized, and its characterization was performed using several spectroscopic...
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Equilibrium in a Bovine Serum Albumin–Pyridoxal-5-phosphate 4-Hydroxybenzoyl Hydrazone–La3+ Ion System
AbstractFluorescence spectrometry is used to study the interaction between hydrazone formed by pyridoxal-5-phosphate and 4-hydroxybenzoic acid...
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Synthesis and ultraviolet/aggregation-induced emission investigation of novel tetraphenylvinyl hydrazone derivatives: efficient multimodal chemosensors for fluoride ion
Herein, three novel tetraphenylethylene hydrazone chemosensors TC12, SC16 , and TC16 are prepared for the selective detection of F − . Two NH and one...
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Design and synthesis of novel ureido and thioureido conjugated hydrazone derivatives with potent anticancer activity
BackgroundCompounds possessing urea/thiourea moiety have a wide range of biological properties including anticancer activity. On the other hand,...
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Carboligation of 5-(hydroxymethyl)furfural via whole-cell catalysis to form C12 furan derivatives and their use for hydrazone formation
BackgroundBiobased 5-(hydroxymethyl)furfural (5-HMF) is an important platform that offers numerous possibilities for upgrading to a range of...
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Tridentate xanthene-based hydrazone ligands and their mononuclear transition metal complexes: synthesis, anti-malarial, antimicrobial and molecular docking studies
In the search of potential multi-target medicinal agents, new NOO-tridentate hydrazone ligands (H 2 L 1 –H 2 L 4 ) ( 1 – 4 ) and their transition metal(II)...
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Protolytic Equilibrium Constants in Aqueous Solutions of Pyridoxal-5'-Phosphate Hydrazone and L-Tyrosine
AbstractProtolytic equilibrium constants in an aqueous solution of pyridoxal-5'-phosphate hydrazone and L-tyrosine are determined...
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Synthesis, characterization, spectroscopic properties and antihypertensive activity of 4-chlorobenzaldehyde hydralazine hydrazone and its metal complexes
A hydrazone ligand, 4-chlorobenzaldehyde hydralazine hydrazone (LH), has been synthesized. Our initial attempts to synthesize Co +2 , Ni +2 , Cu +2 and Zn +2...
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Self-Assembled Co(II) and Zn(II) Complexes with Soluble Bis(Hydrazone)Thiopyrimidine-Based Ligands: Electrochemical and Temperature-Dependent Properties
AbstractHerein, two bis(hydrazones) based on a pyridine-hydrazone-pyrimidine-hydrazone-pyridine ( py-hyz-pym-hyz-py ) template have been synthetized....
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The Photoactive Hydrazone-Linked Covalent Organic Frameworks for Photocyclization Approach to Phenanthridine Derivatives
Covalent organic frameworks (COFs) with precise designable structures are becoming popular semiconductor materials for photocatalytic applications....
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Hydrazone bond-oriented molecularly imprinted nanocomposites for the selective separation of protein via the well-defined recognition sites
The development of hydrazone bond-oriented epitope imprinting strategy is reported to synthesize the polymeric binders for the selective recognition...
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Immobilized magnetic copper hydrazone complexes for oxidation of styrene to benzaldehyde by tert-butylhydroxyperoxide: an experimental and theoretical approach
New copper hydrazone complexes [CuL 1 (OAc)](OAc), and [CuL 2 (OAc)], (L 1 and HL 2 = Schiff base of benzhydrazide with 2-pyridine and 2-hydroxy 3-methoxy...
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Synthesis, spectral analysis, DFT-assisted studies, in vitro antioxidant and antimicrobial activity of transition metal complexes of hydrazone ligands derived from 4-nitrocinnemaldehyde
Here, we report a new series of Co(II), Ni(II), Cu(II) and Zn(II) metal complexes (1–20) derived from hydrazone ligands...
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Synthesis and Antimicrobial Activity of Novel Hydrazone and 1,2,4-Triazole-3-thione Derivatives
AbstractNovel hydrazone and 1,2,4-triazole-3-thione derivatives were obtained via the reaction of N 1 , N 3 ,2-triaryl-6-hydroxy-6-methyl-4-oxocyclohexane...