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In silico Studies on PPARγ Agonistic Heterocyclic Systems
Several heterocyclic derivatives like oxazolidinediones, thiazolidinediones, tetarazoles, phenoxazines, etc. are being developed for the treatment...
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Ruthenium-Catalyzed Synthesis of Heterocyclic Compounds
Heterocyclic compounds have been synthesized by means of stoichiometric reagents under acidic or basic conditions. Recent progress of homogeneous...
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Bioactive Heterocyclic Alkaloids of Marine Origin
Many kinds of alkaloids with extraordinary structures and significant biological activities have been isolated from marine organisms. This work...
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Recent advances in the chemistry and applications of N-heterocyclic carbenes
N-Heterocyclic carbenes, despite being isolated and characterized three decades ago, still capture scientists’ interest as versatile, modular and...
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Synthesis of Biologically Active Heterocyclic Stilbene and Chalcone Analogs of Combretastatin
Combretastatin A-4 (CA-4, 7) has had a major impact in the field of medicinal chemistry as a potent bioactive molecule that binds to the...
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Electrophilic and Oxidative Fluorination of Heterocyclic Compounds: Contribution to Green Chemistry
AbstractLiterature data on electrophilic and oxidative fluorination of heterocyclic compounds have been analyzed in terms of the “green” chemistry...
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Producing N-Heterocyclic Compounds from Lignocellulosic Biomass Feedstocks
Major components of lignocellulosic biomass are cellulose, hemicellulose, lignin and these bio-macromolecules are composed of C, H and O atoms. In...
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The Use of N-Heterocyclic Carbenes as Ligands in Palladium-Mediated Catalysis
Recent developments in the use of N-heterocyclic carbenes (NHC) as ligands in palladium-mediated transformations are described. These versatile...
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Conformational Aspects and Interaction Studies of Heterocyclic Drugs
Drug discoveries require the iterative synthesis—along with structural studies—of numerous individual analogues of biologically and medicinally...
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Indole as a Versatile Building Block in Cycloaddition Reactions: Synthesis of Diverse Heterocyclic Frameworks
Indole, a ubiquitous and structurally versatile aromatic compound, has emerged as a key player in the synthesis of diverse heterocyclic frameworks...
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Mechanochemical synthesis of halogenated heterocyclic compounds
Data on the mechanochemical synthesis of halogenated heterocyclic compounds was summarized and analyzed. Special consideration was paid to the...
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Palladium N-Heterocyclic Carbene-Catalyzed Aminations: An Outline
Amination reactions play a pivotal role in synthetic organic chemistry, facilitating the generation of nitrogen-containing scaffolds with broad...
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Recent progress in the application of amidines for the synthesis of N-heterocyclic compounds
Nitrogen-containing heterocycles are an inseparable part of many biologically active compounds. Therefore, the synthesis of these structures is of...
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Ruthenium-Promoted Radical Processes Toward Fine Chemistry
Ruthenium holds a prominent position among the many transition metals used in radical chemistry. The dichlorotris(triphenylphosphine) complex...
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The Chemistry of 2-(1H)-Pyrazinones in Solution and on Solid Support
An overview on the microwave-enhanced synthesis and decoration of the 2(1H)-pyrazinone system is presented. Scaffold decoration using...
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Growing Impact of Ionic Liquids in Heterocyclic Chemistry
In the quest for replacing the conventional toxic organic solvents, a continual effort has been made in fabricating a solvent that is versatile,...
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Fluorinated 1,2,4-triketone analogs: new prospects for heterocyclic and coordination chemistry
The review is focused on the synthetic approaches to polyfluoroalkylated acetal-functionalized β-diketones and their cyclic derivatives (furan-3(2 H )-o...
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Synthesis, biological evaluation and molecular docking studies of new hybrids of α-tocopherol and aryl/heterocyclic group through 1,2,3-triazole spacer
A new series of hybrids of α-tocopherol and aryl/heterocyclic moieties through 1,2,3-triazole linker were made by rationally combining a biologically...
