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Desorption electrospray ionization and matrix-assisted laser desorption/ionization as imaging approaches for biological samples analysis
The imaging of biological tissues can offer valuable information about the sample composition, which improves the understanding of analyte...
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Examining functional group-dependent effects on the ionization of lignin monomers using supercritical fluid chromatography/electrospray ionization mass spectrometry
The chemical and biological conversion of biomass-derived lignin is a promising pathway for producing valuable low molecular weight aromatic...
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A 3D-printed sub-atmospheric pressure electrospray ionization source for robust, facile, and flexible mass spectrometry analysis
The operation and performance of electrospray ionization (ESI) is affected by the surrounding environment. In this study, a compact sub-atmospheric...
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Plastic probe electrospray ionization mass spectrometry developed for rapid fingerprint profile of biological samples without pretreatment
A triangular-shaped flat plastic substrate probe was prepared for direct electrospray ionization mass spectrometry (ESI–MS) for analysis of untreated...
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Development of a dual-electrospray ionization source with in-line absorbance-based voltage control
Emitter tip arrays for electrospray ionization have been used for a variety of MS sample introduction purposes, including detection of multiple...
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Application of infrared matrix-assisted laser desorption electrospray ionization mass spectrometry for morphine imaging in brain tissue
Here, we present a method developed for the analysis of spatial distributions of morphine in mouse brain tissue using infrared matrix-assisted laser...
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Development of a rapid-fire drug screening method by probe electrospray ionization tandem mass spectrometry for human urine (RaDPi-U)
Drug screening tests are mandatory in the search for drugs in forensic biological samples, and immunological methods and mass spectrometry (e.g., gas...
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Evaluating the “wrong-way-round” electrospray ionization of antiretroviral drugs for improved detection sensitivity
The presence of antiretroviral drugs (ARVDs) in the aquatic environment poses a significant health risk to the ecosystem. The dilution of these...
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Study of the Fragmentation of the Antiviral Drug Triazavirin in a Collision Cell under Electrospray Ionization Conditions
AbstractAzoloazines possess a wide spectrum of biological activity. For the analysis of new drugs of the azoloazine series, reliable methods of...
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Determination of Seven Biogenic Amines in Tuna with High-Performance Liquid Chromatography Coupled to Electrospray Ionization Ion Mobility Spectrometry
Tuna is one of the most popular fish and therefore among the most commercially valuable seafood. However, inadequate refrigeration during the whole...
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Release of nanodiscs from charged nano-droplets in the electrospray ionization revealed by molecular dynamics simulations
Electrospray ionization (ESI) is essential for application of mass spectrometry in biological systems, as it prevents the analyte being split into...
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Development of a Specialized Mass Spectrometer for Measuring the Lithium Isotopic Ratio Using Electrospray Ionization with Controlled In-Source Fragmentation and Atomization (ERIAD)
AbstractWe developed a specialized mass-spectrometer for measuring the lithium isotopic ratio using electrospray ionization with controlled in-source...
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In situ fabrication of covalent organic frameworks on solid-phase microextraction probes coupled with electrospray ionization mass spectrometry for enrichment and determination of androgens in biosamples
Solid-phase microextraction (SPME) coupled with electrospray ionization mass spectrometry (ESI-MS) was developed for rapid and sensitive...
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Rapid On-Site Detection of Various Amphetamine-Type Drugs in Human Urine and Hair by Portable Pulsed Direct Current Electrospray Ionization Mass Spectrometry
AbstractHerein, a new method for the simultaneous rapid on-site detection of various amphetamine (AM)-type drugs in human urine and hair samples is...
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Direct analysis of biodegradable chelating agents based on liquid chromatography/electrospray ionization mass spectrometry using a metal-free hydrophilic interaction liquid chromatographic column
Recently, biodegradable aminopolycarboxylic acid chelating agents have attracted attention as an alternative to environmentally persistent chelating...
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Estimation of the concentrations of hydroxylated polychlorinated biphenyls in human serum using ionization efficiency prediction for electrospray
Hydroxylated PCBs are an important class of metabolites of the widely distributed environmental contaminants polychlorinated biphenyls (PCBs)....
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Observation of charged droplets from electrospray ionization (ESI) plumes in API mass spectrometers
Electrospray ionization (ESI) generates bare analyte ions from charged droplets, which result from spraying a liquid in a strong electric field....
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Rapid analysis of untreated food samples by gel loading tip spray ionization mass spectrometry
Rapid, efficient, versatile, easy-to-use, and non-expensive analytical approaches are globally demanded for food analysis. Many ambient ionization...
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Understanding the electrospray ionization response factors of per- and poly-fluoroalkyl substances (PFAS)
Per- and polyfluoroalkyl substances (PFAS) are used extensively in commercial products. Their unusual solubility properties make them an ideal class...
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Quantitative imaging of natural products in fine brain regions using desorption electrospray ionization mass spectrometry imaging (DESI-MSI): Uncaria alkaloids as a case study
Uncaria species (Rubiaceae) are used as traditional Chinese medicines (TCMs) to treat central nervous system (CNS) diseases, and monoterpene indole...
