Search
Search Results
-
Cyclocondensation of Methyl 5-Methyl-1-(2-oxo-2-phenylethyl)-1H-pyrazole-3-carboxylate. Synthesis of a New 18-Membered Nitrogen Macroheterocycle
AbstractA method has been developed for the synthesis of a new 18-membered nitrogen macroheterocycle via acid-catalyzed cyclocondensation of 1-[(2 E , Z )-2-hydrazinylidene-2-phenylethyl]-5-methyl-1...
-
Magnetite and Cerium Dioxide Nanocomposites as Catalysts for Cyclocondensation Reactions of β-Dicarbonyl Compounds in the Synthesis of Pyrimidines and m-Terphenyls
AbstractThe effective methods for obtaining Fe 3 O 4 /CeO 2 , Fe 3 O 4 (TEOS)CeO 2 nanocomposites with cerium dioxide content from 38 to 82% and from 32 to...
-
Cyclocondensation of anthranilic acids with generated in situ methyl pyrimidine-2-carbimidate in the synthesis of 2-(pyrimidin-2-yl)quinazolin-4(3H)-ones
The possibilities of the synthesis of new derivatives of quinazolin-4(3 H )-ones by the reactions of different functionalized anthranilic acids with...
-
Catalyst-free and solvent-free visible light irradiation-assisted Knoevenagel–Michael cyclocondensation of aryl aldehydes, malononitrile, and resorcinol at room temperature
AbstractCatalyst-free and solvent-free three-component tandem approach can synthesize 2-amino-4 H -chromene scaffolds by Knoevenagel–Michael...
-
[3+3] Cyclocondensation of β-carbonyl-substituted 1H-benzo[f]chromenes with 3-amino-1,2,4-triazoles: synthesis of [1,2,4]triazolo[1,5-a]pyrimidines
The reaction of β-carbonyl-substituted 1 H -benzo[ f ]chromenes with 3-amino-1,2,4-triazoles provides a new avenue for the preparation of...
-
Synthesis of 2-aminophenoxazin-3-ones by photolysis of 2-azidophenol and 2-aminophenols
The synthetic method of 2-amino-3 H -phenoxazin-3-one derivatives through the photoinitiated cyclocondensation of 2-azidophenol with substituted...
-
Synthetic approaches toward 2,3-dihydroquinazolinones (microreview)
As an outlook of the vast development achieved in past two decades, this microreview intends to afford a selected illustration of the recent progress...
-
Recent trends in the synthesis of ‘Zolimidine’: a mini-review
Zolimidine, branded as ‘Solimidin’ is a gastroprotective drug based on imidazo[1,2- a ] pyridine (imidazo[1,2- a ]pyridine) nucleus. The limited...
-
An Ecofriendly Strategy for the Synthesis of Polyfunctionalized 4H-Pyrans in Aqueous Ethanol: Comparative Study of M/ZSM-5 (M = Cu, Fe, and Ag) Nanocatalysts in the Cyclocondensation Protocol
AbstractA Cu–Ag/ZSM-5 bimetalliclic nanocatalyst–accelerated facile in situ one-step three-component coupling reaction of aromatic aldehydes,...
-
Synthesis of N-Benzothiazolyl-4-nitrosopyrazoles
AbstractThe cyclocondensation of 2-hydrazinylbenzothiazole with 2-(hydroxyimino)-1,3-diketones, leading to previously unknown 3-R 2 -5-R 1 -1-(benzothiaz...
-
A regioselective synthesis of 5-difluoromethyl- and 7-difluoromethyl-substituted pyrazolo[1,5-a]pyrimidines
The cyclocondensation of 3,4-substituted 5-aminopyrazoles with unsymmetrical 1,3-dicarbonyl compounds containing the difluoromethyl group in acetic...
-
Synthesis of 3-dinitromethyl-1,2,4-oxadiazoles from dinitroacetamidoximes
It was demonstrated that the amidoxime moiety of potassium salt of dinitroacetamidoxime is capable of cyclocondensation to form the 1,2,4-oxadiazole...
-
5-Alkylamino-7-aminoazolo[1,5-a]pyrimidine-6-carbonitriles: synthetic strategies and anticancer activity in vitro
The design of novel antagonists for adenosine A 2a receptor (A 2a AR) is a promising strategy for the development of new-generation anticancer agents....
-
Cyclocondensation of 5-chloro-4-formylpyrrole-3-carboxylates with arylamines. Synthesis and fluorescent properties of pyrrolo[2,3-b]quinoline-3-carboxylates and their benzo[f] analogs
5-Chloro-4-formylpyrrole-3-carboxylates react with anilines or β-naphthylamine when heated in DMF under reflux to form ethyl pyrrolo[2,3- b ]quinoline-3...
-
Catalytic synthesis of spiromacrocyclic diperoxides based on α,ω-diols
Cyclocondensation reaction of linear α,ω-diols (C 3 , C 5 , C 6 , and C 8 ) with 1,1-dihydroperoxycycloalkanes and formaldehyde with the participation of...
-
Antibacterial efficacy of pyranopyrimidinone derivatives synthesized using a facile one-pot reaction
Discovering new and effective medications against resistant bacteria is an urgent need to save modern medicine, as well as prevent and treat...
-
Synthesis and evaluation of cytotoxicity of S-substituted 5-sulfanylmethyl(ethyl)-1,3,4-thiadiazol-2-amines
A general and efficient method for the synthesis of S-substituted 5-sulfanylmethyl(ethyl)-1,3,4-thiadiazol-2-amines via cyclocondensation of...
-
Eco-friendly synthesis of substituted tetrahydroquinolines as potential ecdysone receptor agonists
New eco-friendly approaches were proposed for the synthesis of cis -cyclopentene-annulated heterocyclic compounds containing a tetrahydroquinoline...
-
A new role for solar energy as a renewable energy source for catalyst-solvent free gram-scale synthesis of pyrano[2,3-d]pyrimidine scaffolds
In the realm of chemistry, increased energy consumption as a result of population development and industrialisation necessitates the usage of...
-
Synthesis of pyran-annulated heterocyclic system under catalyst-solvent-free conditions using solar energy as renewable energy source
The Knoevenagel-Michael cyclocondensation of aldehydes, malononitrile, and resorcinol through a three-condensation domino reaction can be utilized to...
