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Palladium-Catalyzed Cyclization via Carbopalladation and Acylpalladation
Over the past two decades, cyclic carbopalladation and related cyclic acylpalladation of alkenes, allenes, alkynes, and related π complexes...
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Palladium-Catalyzed Two- or Three-Component Cyclization of Functionalized Allenes
This review summarizes the Pd-catalyzed cyclization of an allene bearing a nucleophilic functionality with an organic or inorganic halide, and the...
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Coumarin-3-carboxylic acid: C3/C4-functionalizations and cyclization reactions
AbstractDue to the presence of a carboxyl group, coumarin-3-carboxylic acid can easily participate in C3-, and C4-functionalization, as well as...
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Ni-catalyzed highly regio- and stereo-selective diborylative cyclization of 1,6-enynes with diboron reagent
The Ni-catalyzed highly selective diborylative cyclization of 1,6-enynes with diboron reagent has been developed. When pinB-Bdan was used, multiple...
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Regioselective electrochemical radical cascade cyclization of internal alkynes to selenated and trifluoromethylated dihydropyran
Dihydropyran (DHP) compounds are not only found in natural products and bioactive molecules, but also serve as important precursors in organic...
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Reactivity of alicyclic 1,5,9-triketones toward five-, six-, and seven-membered rings in acidic medium. Stereochemistry of intramolecular cyclization products
Among nine alicyclic 1,5,9-triketones with differently fused 5-, 6-, and 7-membered rings in the molecule, existing as mixtures of 3–6 diastereomers,...
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Synthesis of Substituted Quinolines through Bismuth-Catalyzed Cyclization
AbstractThe synthesis of quinoline derivatives through bismuth-catalyzed cyclization of phenylacetylene with ethyl 2-(arylimino)acetates has been...
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Unified short syntheses of oxygenated tricyclic aromatic diterpenes by radical cyclization with a photoredox catalyst
The biomimetic two-phase strategy employing polyene cyclization and subsequent oxidation/substitution is an effective approach for divergent...
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Chemoenzymatic tandem cyclization for the facile synthesis of bicyclic peptides
Bicyclic peptides exhibit improved metabolic stabilities and target specificities when compared to their linear or mono-cyclic counterparts; however,...
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The role of aromaticity in the cyclization and polymerization of alkyne-substituted porphyrins on Au(111)
Aromaticity is an established and widely used concept for the prediction of the reactivity of organic molecules. However, its role remains largely...
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Stereodivergent photobiocatalytic radical cyclization through the repurposing and directed evolution of fatty acid photodecarboxylases
Despite their intriguing photophysical and photochemical activities, naturally occurring photoenzymes have not yet been repurposed for new-to-nature...
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Regioselective access to polycyclic N-heterocycles via homogeneous copper-catalyzed cascade cyclization of allenynes
Polycyclic N-heterocycles are important structural motifs commonly found in bioactive compounds, however, their selective construction via the...
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CuCl-Catalyzed Cyanoalkylation/Cyclization to Construct Indolo[2,1-a]isoquinoline Derivatives
AbstractAn efficient copper-catalyzed cyanoalkylation/cyclization strategy was developed for the construction of indolo[2,1- a ]isoquinoline...
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Protonated Mesoporous Aluminosilica Nanospheres Boosting Aza-Michael Cyclization and Diels-Alder Reaction
Mesoporous aluminosilica hollow nanospheres were prepared easily, which possess very strong acid site. The heterogeneous catalyst can be utilized in...
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Multicomponent Cyclization of Ethyl Trifluoroacetoacetate with Acetaldehyde and 1,3-Diamines to Hetero-Fused Pyridines
AbstractA procedure has been developed for the synthesis of cis - and trans -diastereoisomeric partially hydrogenated pyrido[1,2- a ]pyrimidines and...
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Cascade asymmetric dearomative cyclization reactions via transition-metal-catalysis
Catalytic asymmetric dearomatization (CADA) reactions offer an efficient strategy for directly converting aromatic compounds into chiral cyclic...
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Cyclization of L-Leucyl-L-valine Dipeptide in the Crystal Phase under Non-Isоthermal Conditions
AbstractThermal treatment of linear dipeptides in solid state makes it possible to obtain their cyclic analogues in high yield and without additional...
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Reversible pH-dependent cyclization of hydroxy-substituted gem-chloronitroso compounds to isoxazoline N-oxides and 5,6-dihydro-4H-1,2-oxazine N-oxides
Cyclization of hydroxy-substituted gem -chloronitroso compounds under the action of bases affords cyclic nitronates, namely, isoxazoline N -oxides and...
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The cyclization and functionalization reactions involving N-phenacylpyridinium salts
Pyridinium salts have been used as starting materials and intermediates in 1,3-dipolar cycloaddition with dipolarophiles. Among them, N -phenacylpyridi...
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Palladium mediated domino heck redox cyclization of aromatic homoallylic alcohols to methylindanones
3-Methyl indanones are key synthetic building blocks for a variety of natural and useful synthetic compounds. Their synthesis is exceedingly...
