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Bioinformatics Pipeline for Processing Single-Cell Data
Single-cell proteomics can offer valuable insights into dynamic cellular interactions, but identifying proteins at this level is challenging due to...
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Metaproteomic Analysis of Biogas Plants: A Complete Workflow from Lab to Bioinformatics
Metaproteomics represents a promising and fast method to analyze the taxonomic and functional composition of biogas plant microbiomes. However,...
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Bioinformatics Analysis of Actin Interactome: Characterization of the Nuclear and Cytoplasmic Actin-Binding Proteins
Actin is present in the cytoplasm and nucleus of every eukaryotic cell. In the cytoplasm, framework and motor functions of actin are associated with...
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Bioinformatics Toward Improving Bioremediation
Environmental pollution has become a major issue of concern. With the rapid growth of industrialization, agricultural practices, and energy...
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From Data to Discoveries: Bioinformatics Strategies for Analyzing Metabolomics, Proteomics, and Gene Editing Data
The integration of computational and experimental methodologies has propelled the field of bioinformatics toward a comprehensive understanding of...
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Mechanisms of Ferroptosis-Related Genes in Gallbladder Cancer Based on Bioinformatics Analysis
Gallbladder Cancer (GBC) is a lethal malignancy with limited treatment options and poor prognosis. Recent studies have emphasized the role of...
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Bioinformatics Analysis and Experimental Validation for Exploring Key Molecular Markers for Glioblastoma
Glioblastoma (GBM) is the most common primary intracranial malignancy with a very low survival rate. Exploring key molecular markers for GBM can help...
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Looking for Plant microRNAs in Human Blood Samples: Bioinformatics Evidence and Perspectives
Literature has proposed the existence of a cross kingdom regulation (CRK) between human and plants. In this context, microRNAs present in edible...
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Bioinformatics and its role in the study of the evolution and probiotic potential of lactic acid bacteria
Due to their numerous well-established applications in the food industry, there have been many studies regarding the adaptation and evolution of...
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Bioinformatics Research and qRT-PCR Verify Hub Genes and a Transcription Factor-MicroRNA Feedback Network in Intervertebral Disc Degeneration
The present study explores the potentials of bioinformatics analysis to identify hub genes linked to intervertebral disc degeneration (IDD) and...
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Application of Knowledge Information Processing Methods to Biochemical Engineering, Biomedical and Bioinformatics Fields
In biochemical and biomedical engineering fields there are a variety of phenomena with many complex chemical reactions, in which many genes and...
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Searching Epitope-Based Vaccines Using Bioinformatics Studies
Epitope-based vaccines is one of the most recent methodologies applied in bioinformatics studies. This strategy consists of identifying regions of...
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Identification of chemoresistance associated key genes-miRNAs-TFs in docetaxel resistant breast cancer by bioinformatics analysis
The present study aimed to identify the differentially expressed genes (DEGs) and enriched pathways in docetaxel (DTX) resistant breast cancer cell...
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A novel starch-active lytic polysaccharide monooxygenase discovered with bioinformatics screening and its application in textile desizing
BackgroundLytic polysaccharide monooxygenases (LPMOs) catalyzing the oxidative cleavage of different types of polysaccharides have potential to be...
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Bioinformatics and Machine Learning Methods Identified MGST1 and QPCT as Novel Biomarkers for Severe Acute Pancreatitis
Severe acute pancreatitis (SAP) is a life-threatening gastrointestinal emergency. The study aimed to identify biomarkers and investigate molecular...
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Entropy-Driven, Integrative Bioinformatics Approaches Reveal the Recent Transmission of the Monkeypox Virus from Nigeria to Multiple Non-African Countries
Monkeypox virus (mpox) has currently affected multiple countries around the globe. This study aims to analyze how the virus spread globally. The...
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Identification of Potential Hub Genes Related to Acute Pancreatitis and Chronic Pancreatitis via Integrated Bioinformatics Analysis and In Vitro Analysis
Acute pancreatitis (AP) and chronic pancreatitis (CP) are considered to be two separate pancreatic diseases in most studies, but some clinical...
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The Gene Network Correlation Analysis of Obesity to Type 1 Diabetes and Cardiovascular Disorders: An Interactome-Based Bioinformatics Approach
The current study focuses on the importance of Protein–Protein Interactions (PPIs) in biological processes and the potential of targeting PPIs as a...
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Bioinformatics Analysis of miR-181a and Its Role in Adipogenesis, Obesity, and Lipid Metabolism Through Review of Literature
The miRNAs regulate various biological processes in the mammalian body system. The role of miR-181a in the development, progression, and expansion of...
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Novel Bioinformatics Strategies Driving Dynamic Metaproteomic Studies
Constant improvements in mass spectrometry technologies and laboratory workflows have enabled the proteomics investigation of biological samples of...