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Engineering yeast mitochondrial metabolism for 3-hydroxypropionate production
BackgroundWith unique physiochemical environments in subcellular organelles, there has been growing interest in harnessing yeast organelles for...
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Harnessing Cellular Organelles to Bring New Functionalities into Yeast
Subcellular organelles in eukaryotes are unique and specialized physiochemical compartments that separate specific metabolic reactions from the rest...
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Changes in ATPase activity, antioxidant enzymes and proline biosynthesis in yeast Candida guilliermondii NP-4 under X-irradiation
This study investigates the effects of X-radiation on ATPase activity and antioxidant enzyme activity, particularly enzymes involved in proline...
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Shared and more specific genetic determinants and pathways underlying yeast tolerance to acetic, butyric, and octanoic acids
BackgroundThe improvement of yeast tolerance to acetic, butyric, and octanoic acids is an important step for the implementation of economically and...
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Enhancing freeze–thaw tolerance in baker's yeast: strategies and perspectives
Frozen dough technology is important in modern bakery operations, facilitating the transportation of dough at low temperatures to downstream sales...
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Engineering yeast with a light-driven proton pump system in the vacuolar membrane
BackgroundThe supply of ATP is a limiting factor for cellular metabolism. Therefore, cell factories require a sufficient ATP supply to drive...
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Whole Cell Yeast-Based Biosensors
Analyte detection is a major component of fieldwork, environmental surveillance, and health protection, but lack of resources or access to...
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Carbon nanotubes functionalized with α-aminoisobutyric acid-containing peptide increase gene delivery efficiency in plant mitochondria
AbstractFunctionalized carbon nanotubes have shown tremendous promise in the field of plant biotechnology for genetic engineering and cargo delivery;...
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Development of an industrial yeast strain for efficient production of 2,3-butanediol
As part of the transition from a fossil resources-based economy to a bio-based economy, the production of platform chemicals by microbial cell...
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Coupling Glucose Phosphorylation to Oxygen in Brain Mitochondria: Would It Be a Redox Set Point?
The brain is a crucial organ that integrates very rapidly several complex sensory functions contributing to the fitness of different mammal species...
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Construction of a Membrane Yeast Two-Hybrid Library and Screening of MsPYR1-Like Interacting Proteins in Malus sieversii
To investigate the biological effects of the ABA receptor pyrabactin resistance 1-like ( PYR1-like ) in Malus sieversii seeds, the proteins interacting...
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Improving furfural tolerance in a xylose-fermenting yeast Spathaspora passalidarum CMUWF1–2 via adaptive laboratory evolution
BackgroundSpathaspora passalidarum is a yeast with the highly effective capability of fermenting several monosaccharides in lignocellulosic...
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Glucose feeds the tricarboxylic acid cycle via excreted ethanol in fermenting yeast
Ethanol and lactate are typical waste products of glucose fermentation. In mammals, glucose is catabolized by glycolysis into circulating lactate,...
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Oxygenation influences xylose fermentation and gene expression in the yeast genera Spathaspora and Scheffersomyces
BackgroundCost-effective production of biofuels from lignocellulose requires the fermentation of d -xylose. Many yeast species within and closely...
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Methanol bioconversion into C3, C4, and C5 platform chemicals by the yeast Ogataea polymorpha
BackgroundOne carbon (C1) molecules such as methanol have the potential to become sustainable feedstocks for biotechnological processes, as they can...
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Incorporating, Quantifying, and Leveraging Noncanonical Amino Acids in Yeast
Genetic code expansion has allowed for extraordinary advances in enhancing protein chemical diversity and functionality, but there remains a critical...
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Engineering cofactor supply and recycling to drive phenolic acid biosynthesis in yeast
Advances in synthetic biology enable microbial hosts to synthesize valuable natural products in an efficient, cost-competitive and safe manner....
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Vitamin B6, B12 and folate modulate deregulated pathways and protein aggregation in yeast model of Huntington disease
Huntington’s disease (HD) is an incurable and progressive neurodegenerative disease affecting the basal ganglia of the brain. HD is caused due to...
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Production of pyruvic acid with Candida glabrata using self-fermenting spent yeast cell dry powder as a seed nitrogen source
Pyruvic acid is an important organic acid and a key industrial raw material. It is widely used in the chemical, agricultural, and food fields. Candida...
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Engineering the oleaginous yeast Candida tropicalis for α-humulene overproduction
Backgroundα-Humulene is a plant-derived monocyclic sesquiterpenoid with multiple pharmacological activities, and far-reaching potential for the...
