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Identification of Phyto-Compounds from Ilex kudingcha as Inhibitors of Sterol-14α-Demethylase Protease: A Computational Approach Against Chagas Disease
Trypanosoma cruzi causes chagas disease, a life threating disease in non-endemic and endemic regions globally, the life cycle of T. cruzi strictly...
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Therapeutic Effect of Desmodium caudatum Extracts on Alleviating Diabetic Nephropathy Mice
Desmodium caudatum extracts (DCE) were investigated for their potential therapeutic effects on diabetic nephropathy (DN). In our study, the high-fat...
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Effects of SCFAs and TMAO on non-alcoholic fatty liver disease indicating the therapeutic benefits of plant-based diet, and supplemental prebiotics, probiotics and synbiotics
This review discusses the effects of short-chain fatty acids (SCFAs) and trimethylamine-N-oxide (TMAO) on metabolic diseases, focusing on...
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Recent Progress in Microalgal Squalene Production and Its Cosmetic Application
Squalene, [oxidized form squalane] is a terpenoid with biological activity that produced by animals and plants. In the human body, a significant...
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Hypolipidemic Effects of Soy Protein and Isoflavones in the Prevention of Non-Alcoholic Fatty Liver Disease- A Review
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and affects about 25% of the population globally. Obesity and...
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Role of Bioactive Compounds in Hormonal Bioregulation
Bioactive compounds possess the ability to interact with living tissues and impact cellular activities. Concerning human beings, these bioactive... -
New pentacoordinated diorganotin(IV) complexes of o-aminophenol based Schiff base ligands: Synthesis, characterization, antioxidant, antimicrobial and molecular docking studies
In the present study, sixteen new diorganotin(IV) complexes of the general formula R 2 SnL 1−4 where, R = methyl, ethyl, butyl phenyl and L 1 = 4-chloro-2-(((2-hydroxy-5-(...
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Dietary Phytosterols
Phytosterols are plant chemicals and steroids with over 250 varieties isolated so far from different plant species. They are accounted for their... -
Dietary Phytosterols
Phytosterols are plant chemicals and steroids with over 250 varieties isolated so far from different plant species. They are accounted for their... -
Nanomaterials Synthesis Using Saponins and Their Applications
Nanoscience is an exponentially develo** field where multidisciplinary principles intersect in formulating notable innovations and discoveries.... -
Phytosterols as Functional Compounds and Their Oxidized Derivatives
Plant sterols, also called phytosterols, are plant-derived compounds that structurally and functionally resemble cholesterol in mammals. These... -
PI(4,5)P2 and Cholesterol: Synthesis, Regulation, and Functions
Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) is the most abundant membrane phosphoinositide and cholesterol is an essential component of the... -
Peony seed oil decreases plasma cholesterol and favorably modulates gut microbiota in hypercholesterolemic hamsters
PurposePeony ( Paeonia spp.) seed oil (PSO) contains a high amount of α-linolenic acid. The effects of PSO on hypercholesterolemia and gut microbiota...
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Saponins in Food
Saponins belong to the group of plant glycosides widely distributed in more than 100 families of both wild and cultivated plants and in some marine... -
Ashwagandha
Withania somnifera (WS), which is known as Ashwagandha, is a plant in the Solanaceae family. Since ancient times it has been using for Ayurvedic... -
Neohesperidin: Biosynthesis, ADME, Biological and Pharmacological Activities
Neohesperidin (NHP) (3′,5,7-trihydroxy- 4′-methoxy flavanone) is a citrus flavonoid with inherent potent pharmacological properties. Neohesperidin... -
Phaseolus vulgaris L. Leaves Increase Short-Chain Fatty Acid (SCFA) Production, Ameliorating Early Metabolic Alterations
High-fat/high-fructose diets promote early metabolic disorders in weight and lipid and glucose metabolism. Bioactive compounds such as polyphenols...
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Fenugreek (Trigonella foenum-graecum): An Overview of Food Uses and Health Benefits
Fenugreek (Trigonella foenum-graecum) is a leguminous plant that is consumed as a spice to improve the flavor of food around the world. Fenugreek has... -
Advances on Resource, Biosynthesis, Biotransformation, Function, and Application of Dihydromyricetin
(+)-Dihydromyricetin (DMY), (2R,3R)-3,3′,4′,5,5′,7-hexahydroxy-2,3-dihydroflavanonol, a flavanonol, has great pharmaceutical and health protective... -
Sodium status is associated with type 2 diabetes mellitus: a systematic review and meta-analysis of observational studies
PurposeThe relationship between sodium intake and the risk of develo** type 2 diabetes mellitus (T2DM) is inconsistent. We, therefore, aimed to...