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Development of a useful single-reference HPLC method for therapeutic drug monitoring of phenytoin and carbamazepine in human plasma
A single reference high-performance liquid chromatographic (SR-HPLC) method was developed and validated for the therapeutic drug monitoring (TDM) of...
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HPLC and HPLC–MS for Qualitative and Quantitative Analysis of Chinese Medicines
Active compounds derived from Chinese medicines (CMs) have already illustrated immense therapeutic potential over an array of different diseases, and...
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High-Performance Liquid Chromatography (HPLC) Analytical Modelling for Measuring the Onion Anthocyanin Profile
This chapter provides a concise overview of the essay on “High-Performance Liquid Chromatography (HPLC) Analytical Modelling for Measuring the Onion...
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Ecofriendly single-step HPLC and TLC methods for concurrent analysis of ternary antifungal mixture in their pharmaceutical products
Two accurate, sensitive, and selective methods for simultaneous determination of miconazole nitrate (MIC), nystatin (NYS), and metronidazole (MET) in...
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Direct Method for Simultaneous Analysis of Cholesterol and Cholesterol Oxides by HPLC in Meat and Meat Products
Cholesterol and cholesterol oxides have numerous implications for human health, highlighting the importance of determining these compounds in highly...
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Development of UME CRM 1008: certified reference material for C-reactive protein
A certified reference material (CRM) specifically designed for C-reactive protein (CRP) measurement in clinical laboratories was produced in this...
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A Complete Analysis Pipeline for the Processing, Alignment and Quantification of HPLC–UV Wine Chromatograms
Elucidating the chemistry of wine would help defining its quality, chemical and sensory characteristics and optimise the wine-making processes....
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HPLC-CAD as a supplementary method for the quantification of related structure impurities for the purity assessment of organic CRMs
In organic purity assessment, chromatography separation with a suitable detector is required. Diode array detection (DAD) has been a widely used...
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Determination of linearized pDNA template in mRNA production process using HPLC
The recent clinical success of messenger RNA (mRNA) technology in managing the Covid pandemic has triggered an unprecedented innovation in production...
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Simultaneous HPLC Quantification of Four Lignan Glycosides in Sesame Seeds with the Single Reference Standard Method
Seven lignans including four lignan glycosides and three lignans were isolated from 70% methanolic extract of defatted sesame seeds. The chemical...
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Inorganic arsenic in seaweed: a fast HPLC-ICP-MS method without coelution of arsenosugars
Seaweed is becoming increasingly popular in the Western diet as consumers opt for more sustainable food sources. However, seaweed is known to...
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Quality monitoring of Shenmai injection by HPLC pharmacodynamic fingerprinting
A probable problem of disconnection between chemical fingerprints and drug effects for TCMs would be contrary to the original intention of...
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Simultaneous Determination of Triterpenic Acids in Jujube Extract Using HPLC–UV Coupled with Multilayer Perceptron Networks
The three triterpenic acids, betulinic acid, oleanolic acid, and ursolic acid, are some of the prominent components with medicinal characteristics in...
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A new HPLC method with multiple detection systems for impurity analysis and discrimination of natural versus synthetic cannabidiol
Cannabidiol (CBD) is the main non-psychoactive phytocannabinoid derived from Cannabis sativa L. It is now an active pharmaceutical ingredient (API),...
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Glycerol-Based Green RP-HPLC Method for Simultaneous Determination of Methionine and Paracetamol in Pharmaceutical Tablets
Methionine and paracetamol are combined in dosage forms due to the ability of methionine to compensate the deficiency in glutathione in hepatic...
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Experimental design optimisation and validation by accuracy profile of a novel method for Hg speciation analysis by HPLC-ICP-MS and application to Total Diet Studies
This study addresses the development and validation of an analytical method for speciation analysis of mercury (inorganic/Hg 2+ and methylmercury/CH 3 Hg
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Simultaneous determination of 14 analgesics in postoperative analgesic solution by HPLC–DAD and LC–MS/MS
A green, efficient, sensitive and accurate detection method by HPLC–DAD and LC–MS/MS was developed and validated for the quantification of morphine,...
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HPLC Fingerprint Combined with Chemometrics and Network Pharmacology for Q-Markers Prediction Analysis of Saposhnikovia divaricata
Saposhnikovia divaricata (SD) has high medicinal and edible value, but relatively little research has been done on its quality markers (Q-markers)....
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Development of matrix-based reference materials for 17 beta-estradiol by the recommended reference method of ID-LC-MS/MS
We developed and evaluated two-level, namely 2017011 and 2017012, serum-based reference materials (RMs) for 17 beta-estradiol (17 β-E2) by the...
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HPLC–MS/MS-based quantification of human monoclonal antibodies targeting SARS-CoV-2 in the presence of endogenous SARS-CoV-2 antibodies in human serum
Antibodies for treatment and prophylaxis against SARS-CoV-2 are needed particularly for immunocompromised individuals, who cannot adequately benefit...
