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Sample multiplexing for increasing throughput for quantification of estrogens in serum by LC–MS/MS
Estrogens are involved in many physiological processes in vivo. The accurate and rapid quantification of estrogens is required for the diagnosis and...
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Sample pooling and incurred samples improve analytical throughput and quality control of lipophilic phycotoxins screening in bivalve mollusks
Lipophilic marine biotoxins (LMBs) are one of the main risks associated with the consumption of mussels and oysters. Sanitary and analytical control...
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Droplet microarray platforms for high-throughput drug screening
AbstractHigh-throughput screening platforms are fundamental for the rapid and efficient processing of large amounts of experimental data....
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Optical-Switch Raman Spectroscopy for High Throughput Screening
Although surface-enhanced Raman spectroscopy (SERS) is a powerful analytical technique with unbeaten sensitivity, the capabilities of SERS have been...
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High-throughput platforms for microextraction techniques
The proposal of high-throughput platforms in microextraction-based approaches is important to offer sustainable and efficient tools in analytical...
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High-throughput process development from gene cloning to protein production
In the post-genomic era, the demand for faster and more efficient protein production has increased, both in public laboratories and industry. In...
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Ultrahigh-throughput screening-assisted in vivo directed evolution for enzyme engineering
BackgroundClassical directed evolution is a powerful approach for engineering biomolecules with improved or novel functions. However, it...
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High-throughput reprogramming of an NRPS condensation domain
Engineered biosynthetic assembly lines could revolutionize the sustainable production of bioactive natural product analogs. Although yeast display is...
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Probing the chemical ‘reactome’ with high-throughput experimentation data
High-throughput experimentation (HTE) has the potential to improve our understanding of organic chemistry by systematically interrogating reactivity...
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Array-Based Multiplex and High-Throughput Serology Assays
The detection of antibody responses using serological tests provides means to diagnose infections, follow disease transmission, and monitor...
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Fully automated sample treatment method for high throughput proteome analysis
The bottom-up strategy for proteome analysis typically employs a multistep sample preparation workflow that suffers from being time-consuming and...
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Magnetic Microtweezers for High-Throughput Bioseparation in Sub-Nanoliter Droplets
Multiomics studies at single-cell level require small volume manipulation, high throughput analysis, and multiplexed detection, characteristics that...
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Rea** the benefits of liquid handlers for high-throughput gene expression profiling in a marine model invertebrate
BackgroundModern high-throughput technologies enable the processing of a large number of samples simultaneously, while also providing rapid and...
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High-throughput and proteome-wide discovery of endogenous biomolecular condensates
Phase separation inside mammalian cells regulates the formation of the biomolecular condensates that are related to gene expression, signalling,...
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High-Throughput Plasma Proteomic Profiling
Plasma and serum are rich sources of proteins that are commonly used for clinical proteome profiling and biomarkers discovery. However,...
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High-Throughput Proteome Profiling of Plasma and Native Plasma Complexes Using Native Chromatography
We describe a high-throughput method for co-fractionation mass spectrometry (CF-MS) profiling for native plasma protein profiling. CF-MS allows the...
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Microfluidics-driven high-throughput phenoty** and screening in synthetic biology: from single cells to cell-free systems
The interdisciplinary nature of synthetic biology merges engineering principles with biology and provides innovative solutions for issues in the...
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High-throughput phase elucidation of polycrystalline materials using serial rotation electron diffraction
Rapid phase elucidation of polycrystalline materials is essential for develo** new materials of chemical, pharmaceutical and industrial interest....
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RNA Structure Determination by High-Throughput Structural Analysis
RNA functions are closely linked with their structures. Therefore, elucidating the secondary structure of RNAs provides crucial information regarding...