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Simultaneous determination of chloramphenicol, stilbenes, and resorcylic acid lactones in pork using UPLC–MS/MS with a C18 cartridge and immunoaffinity microextraction in a packed syringe
The aim of this study was to establish an analytical method for the simultaneous detection of chloramphenicol, stilbenes, and resorcylic acid...
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Engineered and total biosynthesis of fungal specialized metabolites
Filamentous fungi produce a very wide range of complex and often bioactive metabolites, demonstrating their inherent ability as hosts of complex...
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Polyketides from Fungi
Fungal secondary metabolites present a huge scaffold of chemical entities. Many of these substances have played important roles not only in nature,...
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Methods for Macrolactonization of Seco Acids in the Synthesis of Natural and Biologically Active Compounds
AbstractThe review describes the most common macrolactonization reactions, including the activation of one and/or another terminal functional group...
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Simultaneous Identification and Quantitation of 38 Hormonally Growth Promoting Agent Residues in Bovine Muscle by a Highly Sensitive HPLC-MS/MS Method
This work involved the optimization and validation of a quantitative HPLC-MS/MS method to determine 38 hormonally growth promoter residues in bovine...
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Horseradish Peroxidase: Analytical Capabilities in the Determination of Zearalenone
AbstractThe possibility of using the horseradish peroxidase (HRP)–phenol enzyme–substrate system in the development of an amperometric immunoenzyme...
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Naturally Occurring Organohalogen Compounds—A Comprehensive Review
The present volume is the third in a trilogy that documents naturally occurring organohalogen compounds, bringing the total number—from fewer than 25...
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Natural Estrogenic Substances, Origins, and Effects
Some natural substances have been scientifically identified as estrogenic since the late 1930s when they were found to be deleterious at high doses...
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Polyketides
During the evolution of the plant species, several biochemical mechanisms have been raised as adaptation pathways to external abiotic and biotic...
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Marine Natural Products with Bioactivity Against Neglected Tropical Diseases
Neglected tropical diseases (NTDs) are a group of disabling infectious diseases that disproportionately affect middle- and low-income people in...
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Covalent Kinase Inhibitors: An Overview
Covalent targeting has experienced a revival in the last decade, especially in the area of protein kinase inhibitor development. Generally, covalent...
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Secondary Metabolites from Marine-Derived Fungi from China
Marine-derived fungi play an important role in the search for structurally unique secondary metabolites, some of which show promising pharmacological...
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Recent advances in the applications of Wittig reaction in the total synthesis of natural products containing lactone, pyrone, and lactam as a scaffold
AbstractThe Wittig reaction enables the synthesis of an alkene from the reaction of an aldehyde or ketone with the ylide generated from a phosphonium...
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Natural Estrogenic Substances, Origins, and Effects
Some natural substances have been scientifically identified as estrogenic since the late 1930s when they were found to be deleterious at high doses...
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A Fast Quantitative Multi-analyte Method for Growth Promoters in Bovine Meat Using Bead-Disruption, 96-well SPE Clean-up and Narrow-Bore UHPLC-MS/MS Analysis
A new method for detecting low levels of growth promoters in bovine meat was developed with the following goal: easy, fast and sensitive analysis of...
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Fusarium Secondary Metabolism Biosynthetic Pathways: So Close but So Far Away
Fusarium species are casual filamentous fungi, including opportunistic pathogens infecting plants worldwide, but also able to grow as saprotrophs in...
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Lactone Formation in Yeast and Fungi
Lactones are important secondary metabolites for fungi. In this chapter are presented some lactones that are important in biotechnology such as...
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Fusarium Secondary Metabolism Biosynthetic Pathways: So Close but So Far Away
Fusarium species are casual filamentous fungi, including opportunistic pathogens infecting plants worldwide, but also able to grow as saprotrophs in...
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The determination of zearalenone and its major metabolites in endometrial cancer tissues
Endometrial cancer is one of the most commonly diagnosed cancers in women. The search for factors that contribute to the development of cancer cells...
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Determination of estrogenic compounds in milk and yogurt samples by hollow-fibre liquid-phase microextraction-gas chromatography-triple quadrupole mass spectrometry
An environmentally friendly method based on hollow-fibre liquid-phase microextraction (HF-LPME) was developed for the extraction of selected...
