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Pterin-lysine photoadduct: a potential candidate for photoallergy
Photoallergy is a photosensitivity disorder associated with a modified ability of the skin to react to the combined effect of drugs and sunlight. It...
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Laser photo-thermal therapy of epithelial carcinoma using pterin-6-carboxylic acid conjugated gold nanoparticles
Gold nanoparticles functionalized with folic acid toward the internalization into cancer cells have received considerable attention recently. Folic...
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Theoretical determination of two-photon absorption in biologically relevant pterin derivatives
Given the prevalence of fluorescence spectroscopy in biological systems, and the prevalence of pterin derivatives throughout biological systems,...
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A Pterin-FAM-TAMRA Tri-color Fluorescence Biosensor to Detect the Level of KRAS Point Mutation
Monitoring the changes in the level of KRAS point mutation (the concentration fraction of the KRAS point mutated DNA to the total DNA) in clinical...
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Mechanism of molybdate insertion into pterin-based molybdenum cofactors
The molybdenum cofactor (Moco) is found in the active site of numerous important enzymes that are critical to biological processes. The bidentate...
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Exploring the role of flavin-dependent monooxygenases in the biosynthesis of aromatic compounds
Hydroxylated aromatic compounds exhibit exceptional biological activities. In the biosynthesis of these compounds, three types of hydroxylases are...
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Nickel-organo compounds as potential enzyme precursors under simulated early Earth conditions
The transition from inorganic catalysis through minerals to organic catalysis by enzymes is a necessary step in the emergence of life. Our work is...
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Protein Engineering of the Soluble Metal-dependent Formate Dehydrogenase from Escherichia coli
Formate is the most targeted C1 building block and electron carrier in the post-petroleum era. Formate dehydrogenase (FDH), which catalyzes the...
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Carbon dots derived from folic acid attenuates osteoarthritis by protecting chondrocytes through NF-κB/MAPK pathway and reprogramming macrophages
BackgroundOsteoarthritis (OA) is a common joint disorder worldwide which causes great health and economic burden. However, there remains an unmet...
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One Step Synthesis of New Cocrystals of Chloropterin and 5-Deazapterin-6-carboxylic Acid Perchlorate Salts
AbstractSingle crystal X-ray structures of new perchlorate salts of 6-carboxylic acid 5-deaza pterin perchlorates (cdpt) and 6-carboxylic acid...
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Interaction mechanism of novel fluorescent antifolates targeted with folate receptors α and β via molecular docking and molecular dynamic simulations
Eight novel fluorescent antifolates were designed and docked with folate receptors FRα and FRβ. The structures of the complexes were further...
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A highly therapeutic and selective delivery system for curcumin based on nanocellulose and folic acid
Curcumin (CUR) is an emerging natural agent for cancer therapy. However, the low therapeutic efficacy and weak selectivity of CUR still severely...
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Construction of cell factory capable of efficiently converting l-tryptophan into 5-hydroxytryptamine
Backgroundl -Tryptophan ( l -Trp) derivatives such as 5-hydroxytryptophan (5-HTP) and 5-hydroxytryptamine (5-HT), N-Acetyl-5-hydroxytryptamine and...
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Vitamins-Minerals-Additives
After studying this chapter, you will be able to:
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Bioactive Phytochemicals from Castor (Ricinus communis Linneo) Seed Oil Processing By-products
Castor (Ricinus communis Linneo) belongs to the plant family of Euphorbiaceae and is a crop intensively cultivated to produce oil from its seeds....
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UV/Vis absorption spectroelectrochemistry of folic acid
UV/Vis absorption spectroelectrochemistry is a very promising analytical technique due to the complementary information that is simultaneously...
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Systematic identification of trimethoprim metabolites in lettuce
Antibiotics are some of the most widely used drugs. Their release in the environment is of great concern since their consumption is a major factor...
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Weighted gene co-expression network analysis unveils gene networks regulating folate biosynthesis in maize endosperm
Folates are essential elements for human growth and development, and their deficiency can lead to serious disorders. Waxy maize is a rich source of...
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Bioactive Phytochemicals from Castor (Ricinus communis Linneo) Seed Oil Processing By-products
Castor (Ricinus communis Linneo) belongs to the plant family of Euphorbiaceae and is a crop intensively cultivated to produce oil from its seeds....
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Fundamentals of DET-Type Bioelectrocatalysis
This chapter starts by introducing the history of DET-type non-catalytic and bioelectrocatalytic reactions with much attention to the distinction...