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Irradiated microparticles suppress prostate cancer by tumor microenvironment reprogramming and ferroptosis
Immunogenic cell death (ICD) plays a crucial role in triggering the antitumor immune response in the tumor microenvironment (TME). Recently,...
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Photodynamic therapy reduces cell viability, migration and triggers necroptosis in prostate tumor cells
Prostate cancer is the most common cancer in American men, aside from skin cancer. As an alternative cancer treatment, photodynamic laser therapy...
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A black phosphorus nanosheet-based RNA delivery system for prostate cancer therapy by increasing the expression level of tumor suppressor gene PTEN via CeRNA mechanism
BackgroundProstate cancer (PCa) has a high incidence in men worldwide, and almost all PCa patients progress to the androgen-independent stage which...
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Enhanced natural killer cell anti-tumor activity with nanoparticles mediated ferroptosis and potential therapeutic application in prostate cancer
Ferroptosis provides an opportunity to overcome the cancer cell therapeutic resistance and modulate the immune system. Here an interaction between...
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Brevilin A Inhibits Prostate Cancer Progression by Decreasing PAX5-Activated SOX4
Brevilin A possesses inhibitory effects on the development of prostate cancer (PCa); however, the underlying mechanism remains unclear. The present...
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Radiolabeled Integrin αvβ3 Antagonists as Radiopharmaceuticals for Tumor Radiotherapy
Integrins are a family of proteins that facilitate cellular adhesion to and migration on the extracellular matrix proteins found in intercellular...
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Prostate cancer-derived small extracellular vesicle proteins: the hope in diagnosis, prognosis, and therapeutics
Current diagnostic tools for prostate cancer (PCa) diagnosis and risk stratification are insufficient. The hidden onset and poor efficacy of...
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The sensor applications for prostate and lung cancer biomarkers in terms of electrochemical analysis
Prostate and lung cancers are the most common types of cancer and affect a large part of the population around the world, causing deaths. Therefore,...
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A mitochondrion-targeted cyanine agent for NIR-II fluorescence-guided surgery combined with intraoperative photothermal therapy to reduce prostate cancer recurrence
Poorly identified tumor boundaries and nontargeted therapies lead to the high recurrence rates and poor quality of life of prostate cancer patients....
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Co-delivery of Anticancer Drugs Using Polymer-Based Nanomedicines for Lung and Prostate Cancer Therapy
Although there are many treatment advances in oncology, cancer remains the cause of morbidity and mortality worldwide. The most common cancer types...
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Anti-proliferative, Pro-apoptotic, and Chemosensitizing Potential of 3-Acetyl-11-keto-β-boswellic Acid (AKBA) Against Prostate Cancer Cells
Prostate cancer incidences are rising worldwide at an alarming rate. Drug resistance and relapse are two major challenges in the treatment of...
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Sustainable Nanoparticles from Stephania glabra and Analysis of Their Anticancer Potential on 2D and 3D Models of Prostate Cancer
In pursuit of a novel effective treatment for prostate cancer, methanolic extract of Stephania glabra tubers (Sg-ME) was utilized to fabricate silver...
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An insight into the diagnostic, prognostic, and taxanes resistance of double zinc finger and homeodomain factor’s expression in naïve prostate cancer
Currently, clinical biomarkers are urgently needed to improve patient management to guide personal therapy for cancer. In this study, we investigate...
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Spatial MS multiomics on clinical prostate cancer tissues
Mass spectrometry (MS) and MS imaging (MSI) are used extensively for both the spatial and bulk characterization of samples in lipidomics and...
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Interdigitated impedimetric-based Maackia amurensis lectin biosensor for prostate cancer biomarker
Highly specific detection of tumor-associated biomarkers remains a challenge in the diagnosis of prostate cancer. In this research, Maackia amurensis ...
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Nanotechnological strategies for prostate cancer imaging and diagnosis
The high incidence rates and complicated subtypes of prostate cancer (PCa) call for the demand of the precise diagnostic and therapeutic strategies....
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Recent Advances in Designing Porous Carbon Nanomaterial Based for Electrochemical Biosensing Prostate Cancer
Prostate cancer (PCa), is the most prevalent type of cancer and is associated with a high mortality rate. The clinical assessments of cancer proteins...
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In vitro and in vivo comparative study of 68Ga-labeled DOTA-, NOTA-, and HBEDCC-chelated radiotracers targeting prostate-specific membrane antigen
68 Ga-radiolabeled small molecules targeting prostate-specific membrane antigen (PSMA) have been extensively investigated as 68 Ga-positron emission...
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Resveratrol inhibits TRAF6/PTCH/SMO signal and regulates prostate cancer progression
Prostate cancer (PC) is one of the most common types of cancers among men, referring to the uncontrolled growth of the prostate gland. It is...
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Polysaccharide-Based Hydrogels for Bioengineering 3D Tumor Models
Cancer is the leading cause of death worldwide and its incidence is expected to rise. Despite overwhelming efforts to design innovative preclinical...