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Large-scale expansion of human umbilical cord-derived mesenchymal stem cells using PLGA@PLL scaffold
Mesenchymal stem cells (MSCs) are highly important in biomedicine and hold great potential in clinical treatment for various diseases. In recent...
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Impact of Sleepy Stack MOSFETs in CS-VCO on Phase Noise and Lock Performance of PLL
Phase noise, lock range, lock time, and power consumption are becoming the dominant performance parameters in a charge pump phase locked loop...
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A biological antimicrobial agent functionalized bacterial cellulose-based wound dressing
Bacterial cellulose (BC) is a promising biomaterial that has been widely used for wound healing. However, the lack of antimicrobial properties limits...
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Biodegradable sponges based on starch, hyaluronic acid, and poly-l-lysine as potent hemostatic agents
Uncontrolled hemorrhage is a major cause of death in surgical operations; therefore, controlling hemorrhage is a key factor in preserving life. In...
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Hairy bacterial nanocellulose: preparation and bioconjugation with an antibacterial agent
It is hypothesized that during the periodate oxidation of bacterial cellulose (BC), the chains will be cleaved in the amorphous regions. Subsequent...
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Magnetic relaxation switch sensor based on aptamer-modified poly-L-lysine-ferroferric oxide magnetic nanoparticles and graphene oxide for the determination of insecticides in vegetables
A simple and effective graphene oxide-magnetic relaxation switch (GO-MRS) sensor that combines graphene oxide (GO) and aptamer-modified...
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Tuning with Phosphorylcholine Grafts Improves the Physicochemical Properties of PLL/pDNA Nanoparticles at Neutral pH
The improvement of biological properties of polycations is a fundamental step to overcome their limitations as non-viral gene carriers. This work...
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Interaction of Poly(Ethylene Glycol)-b-Poly-L-Lysine Copolymers with DNA Structures: A Thermodynamic Investigation
One focus of our research is to select polycations to deliver oligonucleotides into the cell for the control of gene expression. This work is to...
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Interaction of Poly(Ethylene Glycol)-b-Poly-L-Lysine Copolymers with DNA Structures: A Thermodynamic Investigation
One focus of our research is to select polycations to deliver oligonucleotides into the cell for the control of gene expression. This work is to...
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Preparation of new eco-friendly covalent dynamic network based on polylysine, cellulose nanowhisker dialdehyde, and chitosan for curcumin delivery
Dynamic covalent hydrogels are considered smart materials with a stimuli-sensitive nature and possessing great importance in biomedical applications....
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Development of an anti-infective coating on the surface of intraosseous implants responsive to enzymes and bacteria
BackgroundBacterial proliferation on the endosseous implants surface presents a new threat to the using of the bone implants. Unfortunately, there is...
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Metformin booster adipocyte-targeted gene therapy for the treatment of obesity and related metabolic syndromes
Obesity has become an important public problem that endangers human conditions and urgently needs to be solved. However, most weight-loss drugs on...
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Comparison of blocking reagents for antibody microarray-based immunoassays on glass and paper membrane substrates
Background noise due to nonspecific binding of biomolecules on the assay substrates is one of the most common challenges that limits the sensitivity...
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Amphiphilic Block Copolymer Micelles for Gene Delivery
Gene therapy is a promising method to treat acquired and inherited diseases by introducing exogenous genes into specific recipient cells. Polymeric...
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Modelling and Optimization of Phase Locked Loop under Constrained Channel Length and Width of MOSFETs
CMOS integrated circuits consisting of MOSFETs have tradeoffs among their performance parameters. Hence they need minimization in those tradeoffs...
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Affinity Diversification of a Polymer Probe for Pattern-recognition-based Biosensing Using Chemical Additives
Pattern-recognition-based sensing has attracted attention as a promising alternative to conventional sensing methods that rely on selective...
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Comparison of triblock copolymeric micelles based on α- and ε-poly(L-lysine): a Cornelian choice
Due to the lack of safe carriers for the delivery of small interfering RNA (siRNA), clinical applications of nucleotide-based therapeutics have been...
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Simultaneous glutamine metabolism and PD-L1 inhibition to enhance suppression of triple-negative breast cancer
Blockade of programmed cell death 1 ligand (PD-L1) has been used to treat triple-negative breast cancer (TNBC), and various strategies are under...
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Design and Analysis of Low Power and High Frequency Current Starved Sleep Voltage Controlled Oscillator for Phase Locked Loop Application
This paper presents a current starved sleep voltage-controlled oscillator(VCO) for the Phase Locked Loop (PLL) at high frequency with low power. The...
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Effective delivery of miR-150-5p with nucleus pulposus cell-specific nanoparticles attenuates intervertebral disc degeneration
BackgroundThe use of gene therapy to deliver microRNAs (miRNAs) has gradually translated to preclinical application for the treatment of...
