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Activation of Heme Oxygenase-1 is Involved in the Preventive Effect of Honokiol against Oxidative Damage in Human Retinal Pigment Epithelial Cells
Previous studies have shown that honokiol, a bioactive compound originated from the Magnolia , has beneficial effects on various chronic diseases....
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Physiological Significance of Oxidative Stress and Anti-oxidative System
Free radicals are generated as a result of different chemical reactions occurring in living cells. Excessive production of these free radicals leads...
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The Beneficial Role of Natural Antioxidants in Alleviating Neuroinflammatory Disorders Including Neurodegeneration
The inflammatory response is a highly self-regulated process that arises due to the common consequence of injury or infection and it has been...
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Inflammatory Modulation of miR-155 Inhibits Doxorubicin-Induced Testicular Dysfunction via SIRT1/FOXO1 Pathway: Insight into the Role of Acacetin and Bacillus cereus Protease
Doxorubicin (DOX) is a chemotherapeutic agent that can disrupt testicular function leading to male infertility. This study examined the protective...
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Kaempferol: Advances on Resources, Biosynthesis Pathway, Bioavailability, Bioactivity, and Pharmacology
Kaempferol (KFP) is an antioxidant polyphenol found in fruits and vegetables. Many studies have shown that dietary kaempferol can help reduce the...
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Potentialities of Tannase-Treated Green Tea Extract in Nutraceutical and Therapeutic Applications
Green tea has garnered widespread interest in the past decades due to its content of health-beneficial polyphenols and catechins, besides reportedly...
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Pharmacological Insights into Morin: Therapeutic Applications and Future Perspectives
Morin is a yellow bioactive pigment compound that is abundantly found in various fruits and plants. Similar to other flavonoid derivatives, morin has...
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Plant Tocopherols and Phytosterols and Their Bioactive Properties
Tocopherols and phytosterols are plant-derived fat-soluble bioactive compounds with several health beneficial properties. Tocopherols are mainly...
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Induction of Oxidative Stress in Sirtuin Gene-Disrupted Ashbya gossypii Mutants Overproducing Riboflavin
AgHST 1 and AgHST3 genes encode sirtuins that are NAD + -dependent protein deacetylases. According to previous reports, their disruption leads to the...
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Regulatory Components of Oxidative Stress and Inflammation and Their Complex Interplay in Carcinogenesis
Cancer progression is closely linked to oxidative stress (OS) inflammation. OS is caused by an imbalance between the amount of reactive oxygen...
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Nutritional load in post-prandial oxidative stress and the pathogeneses of diabetes mellitus
Diabetes mellitus affected more than 500 million of people globally, with an annual mortality of 1.5 million directly attributable to diabetic...
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Pregnan X Receptor Functioning under Conditions of Nitrosative Stress
Abstract —Pregnan X receptor (PXR) is a nuclear receptor that plays an important role in the regulation of the expression enzymes of biotransformation...
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Nanoproteomics: An Approach for the Identification of Molecular Targets Associated with Hypoxia
A thorough examination of every protein’s array in the human proteome is necessary to understand the causes, pathophysiology, and possible treatment...
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Nephroprotective effect of polyphenol-rich extract of Costus spicatus in cisplatin-induced nephrotoxicity in Wistar albino rats
Costus spicatus (spiked spiralflag ginger) is traditionally utilised for its advantages such as antidiabetic, antihyperlipidemic, diuretic,...
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Bioactive Compounds and Biological Activities of Turmeric (Curcuma longa L.)
The golden spice turmeric is nature’s multifaceted creation and is popular widely by many names like haldi, Indian saffron, and kitchen queen. It has...
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Nitrosative stress-mediated inhibition of OsDHODH1 gene expression suggests roots growth reduction in rice (Oryza sativa L.)
This study monitored the transcriptional response of OsDHODH1 under nitrosative stress conditions relative to the transcripts accumulations for the...
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The Beneficial Role of Natural Antioxidants in Alleviating Neuroinflammatory Disorders Including Neurodegeneration
The inflammatory response is a highly self-regulated process that arises due to the common consequence of injury or infection and it has been...
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Generation of Species-Specific High-Strength Plasma Activated Water at Neutral pH and its Antimicrobial Characteristics
Understanding the individual effects of species in plasma activated water (PAW) is indeed necessary for its selective application as an antimicrobial...
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Antioxidant and Photoprotective Properties of Neotropical Bamboo Species
Bamboos are known as one of the most important renewable and valuable of all forest resources. Although it has the high species diversity and is...
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Microbial Bioactive Components: Sources, Applications, and Sustainability
Microbial-based bioactive metabolic compounds are a pool of metabolites that have confident positive effects on environment, humans, plants, and...