Search
Search Results
-
Nanobiodevice for Nucleic Acid Sensing
Nanobiodevices, a technology characterized by engineered nanostructures, have attracted extensive interest as a new generation bioanalytical tool...
-
An enzymatic nucleic acid vertical flow assay
Vertical flow assays have been developed in recent years addressing limitations of the lateral flow assays, including limited multiplexing...
-
Aminoglycoside–Nucleic Acid Interactions: The Case for Neomycin
Aminoglycoside antibiotics are bactericidal drugs that have been at the forefront of antimicrobial therapy for almost five decades. The past decade...
-
Structural Selectivity of Drug-Nucleic Acid Interactions Probed by Competition Dialysis
Competition dialysis is a powerful new tool for the discovery of ligands that bind to nucleic acids with structural- or sequence-selectivity. The...
-
One-pot electrochemical detection of foodborne pathogen based on in situ nucleic acid amplification and wash-free assay
A signal amplification electrochemical biosensor chip was developed to integrate loop-mediated isothermal amplification (LAMP) based on in situ...
-
A Lateral Flow Assay for Nucleic Acid Detection Based on Rolling Circle Amplification Using Capture Ligand-Modified Oligonucleotides
We introduce a lateral flow assay (LFA) integrated with a modified isothermal nucleic acid amplification procedure for rapid and simple genetic...
-
Nucleic Acid Conjugates for Biosensing: Design, Preparation, and Application
A nucleic acid conjugate is a hybrid molecule consisting of a nucleic acid and a linked molecule that confers a specific function. The first nucleic...
-
Nucleic Acid Conjugates for Biosensing – Design, Preparation, and Application
A nucleic acid conjugate is a hybrid molecule consisting of a nucleic acid and a linked molecule that confers a specific function. The first nucleic...
-
Nanobiodevice for Nucleic Acid Sensing
Nanobiodevices, a technology characterized by engineered nanostructures, have attracted extensive interest as a new generation bioanalytical tool...
-
Nucleic Acid Based Testing (NABing): A Game Changer Technology for Public Health
Timely and accurate detection of the causal agent of a disease is crucial to restrict suffering and save lives. Mere symptoms are often not enough to...
-
Multiplex detection of clinical pathogen nucleic acids via a three-way junction structure-based nucleic acid circuit
Nucleic acid testing technology has made considerable progress in the last few years. However, there are still many challenges in the clinical...
-
Isothermal nucleic acid amplification and its uses in modern diagnostic technologies
Nucleic acids are prominent biomarkers for diagnosing infectious pathogens using nucleic acid amplification techniques (NAATs). PCR, a gold standard...
-
Synthesis of Mesoporous Silica Nanoparticles for the Delivery of Nucleic Acid Nanostructures
Nanomaterials have been extensively used for the delivery of nucleic acids. This is attributed to the unique features of nanoparticles to carry...
-
Immunomolecular assay based on selective virion capture by spike antibody and viral nucleic acid amplification for detecting intact SARS-CoV-2 particles
BackgroundEffective therapeutics and vaccines for coronavirus disease 2019 (COVID-19) are currently lacking because of the mutation and immune escape...
-
Hexitol Nucleic Acid (HNA): From Chemical Design to Functional Genetic Polymer
Chemically modified nucleic acids have become crucial tools across a diverse range of sciences. They are extensively used not only as diagnostic and...
-
Hexitol Nucleic Acid (HNA): From Chemical Design to Functional Genetic Polymer
Chemically modified nucleic acids have become crucial tools across a diverse range of sciences. They are extensively used not only as diagnostic and...
-
Non-thiolated nucleic acid functionalized gold nanoparticle–based aptamer lateral flow assay for rapid detection of kanamycin
A novel Apt-LFA has been established for kanamycin based on non-thiolated nucleic acid–modified colloidal gold nanoprobe (AuNPs@polyA-DNA). The...
-
Bimodal DNA self-origami material with nucleic acid function enhancement
BackgroundThe design of DNA materials with specific nanostructures for biomedical tissue engineering applications remains a challenge....
-
Special-Purpose Modifications and Immobilized Functional Nucleic Acids for Biomolecular Interactions
Immobilized oligonucleotides form the critical sensing element of many nucleic acid detection methodologies. However, pressures on performance and...
-
A Bifunctional-Blocker-Aided Hybridization Chain Reaction Lighting-Up Self-calibrating Nanocluster Fluorescence for Reliable Nucleic Acid Detection
In this work, we proposed a ratiometric silver nanoclusters (AgNCs) fluorescent assay by designing a bifunctional-blocker-aided hybridization chain...
