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Nitrogen starvation causes lipid remodeling in Rhodotorula toruloides
BackgroundThe oleaginous yeast Rhodotorula toruloides is a promising chassis organism for the biomanufacturing of value-added bioproducts. It can...
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Nitrogen and phosphorus stress as a tool to induce lipid production in microalgae
Microalgae, capable of accumulating large amounts of lipids, are of great value for biodiesel production. The high cost of such production stimulates...
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Comparison of the effects of nitrogen-, sulfur- and combined nitrogen- and sulfur-deprivations on cell growth, lipid bodies and gene expressions in Chlamydomonas reinhardtii cc5373-sta6
BackgroundBiofuel research that aims to optimize growth conditions in microalgae is critically important. Chlamydomonas reinhardtii is a green...
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Expanding the genetic toolbox of Rhodotorula toruloides by identification and validation of six novel promoters induced or repressed under nitrogen starvation
BackgroundThe non-conventional yeast Rhodotorula toruloides is an emerging host organism in biotechnology by merit of its natural capacity to...
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Phosphate limitation enhances malic acid production on nitrogen-rich molasses with Ustilago trichophora
BackgroundAn important step in replacing petrochemical products with sustainable, cost-effective alternatives is the use of feedstocks other than,...
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A new isolate cold-adapted Ankistrodesmus sp. OR119838: influence of light, temperature, and nitrogen concentration on growth characteristics and biochemical composition using the two-stage cultivation strategy
Natural-based chemicals from microalgae such as lipids and pigments are the interests in industries and the bioeconomy. Cold-adapted Ankistrodesmus ...
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Changes in urinary stable nitrogen isotope ratios during controlled short-term energy deficit: a proof-of-principle analysis
PurposeStable isotope ratios of nitrogen (δ 15 N) have previously been shown to increase in human hair during periods of catabolism. The goal of this...
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Lipid accumulation mechanism of Amphora coffeaeformis under nitrogen deprivation and its application as a feed additive in Carassius auratus aquaculture
BackgroundAmphora coffeaeformis , a unicellular diatom, can significantly accumulate lipids under nitrogen (N) limitation. However, the molecular...
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Sulfate limitation increases specific plasmid DNA yield and productivity in E. coli fed-batch processes
Plasmid DNA (pDNA) is a key biotechnological product whose importance became apparent in the last years due to its role as a raw material in the...
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Glutamine involvement in nitrogen regulation of cellulase production in fungi
BackgroundCellulase synthesized by fungi can environment-friendly and sustainably degrades cellulose to fermentable sugars for producing cellulosic...
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Increased triacylglycerol production in Rhodococcus opacus by overexpressing transcriptional regulators
Lignocellulosic biomass is currently underutilized, but it offers promise as a resource for the generation of commercial end-products, such as...
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How do the carbon and nitrogen sources affect the synthesis of β-(1,3/1,6)-glucan, its structure and the susceptibility of Candida utilis yeast cells to immunolabelling with β-(1,3)-glucan monoclonal antibodies?
BackgroundThe need to limit antibiotic therapy due to the spreading resistance of pathogenic microorganisms to these medicinal substances stimulates...
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Development of a stable semi-continuous lipid production system of an oleaginous Chlamydomonas sp. mutant using multi-omics profiling
BackgroundMicroalgal lipid production has attracted global attention in next-generation biofuel research. Nitrogen starvation, which drastically...
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Engineering cytoplasmic acetyl-CoA synthesis decouples lipid production from nitrogen starvation in the oleaginous yeast Rhodosporidium azoricum
BackgroundOleaginous yeasts are able to accumulate very high levels of neutral lipids especially under condition of excess of carbon and nitrogen...
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High production of ectoine from methane in genetically engineered Methylomicrobium alcaliphilum 20Z by preventing ectoine degradation
BackgroundMethane is a greenhouse gas with a significant potential to contribute to global warming. The biological conversion of methane to ectoine...
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‘Mother(Nature) knows best’ – hijacking nature-designed transcriptional programs for enhancing stress resistance and protein production in Yarrowia lipolytica; presentation of YaliFunTome database
BackgroundIn the era of rationally designed synthetic biology, heterologous metabolites production, and other counter-nature engineering of cellular...
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Potassium channel KCN11 is required for maintaining cellular osmolarity during nitrogen starvation to control proper cell physiology and TAG accumulation in Chlamydomonas reinhardtii
BackgroundNitrogen (N) starvation in algae induces a variety of structural and metabolic changes including accumulation of triacylglycerol (TAG)....
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Harnessing redox proteomics to study metabolic regulation and stress response in lignin-fed Rhodococci
BackgroundRhodococci are studied for their bacterial ligninolytic capabilities and proclivity to accumulate lipids. Lignin utilization is a resource...
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A parallel glycolysis provides a selective advantage through rapid growth acceleration
Glycolysis is a universal metabolic process that breaks down glucose to produce adenosine triphosphate (ATP) and biomass precursors. The...
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Transcriptional insights into Chlorella sp. ABC-001: a comparative study of carbon fixation and lipid synthesis under different CO2 conditions
BackgroundMicroalgae's low tolerance to high CO 2 concentrations presents a significant challenge for its industrial application, especially when...
