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Sensitive miRNA Detection for Early Diagnosis of Psoriasis Based on Dual Signal Recycles
MicroRNAs (miRNAs) play a pivotal role in regulating a variety of biological processes and can be used as biomarkers for the early diagnosis of...
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Dual colorimetric strategy for specific DNA detection by nicking endonuclease-assisted gold nanoparticle signal amplification
The continuous spread of invasive alien species, as zebra mussel ( Dreissena polymorpha ), is a major global concern and it is urgent to stop it. Early...
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DNA Technology-assisted Signal Amplification Strategies in Electrochemiluminescence Bioanalysis
Sensitive and accurate detection of biological analytes, such as proteins, genes, small molecules, ions, cells, etc., has been a significant project...
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Isothermal nucleic acid amplification and its uses in modern diagnostic technologies
Nucleic acids are prominent biomarkers for diagnosing infectious pathogens using nucleic acid amplification techniques (NAATs). PCR, a gold standard...
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Improving the fluorometric determination of the cancer biomarker 8-hydroxy-2′-deoxyguanosine by using a 3D DNA nanomachine
The authors describe a fluorometric method for improving the determination of the cancer biomarker 8-hydroxy-2′-deoxyguanosine (8-OHdG). A nicking...
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Label-free detection of microRNA: two-stage signal enhancement with hairpin assisted cascade isothermal amplification and light-up DNA-silver nanoclusters
A method is described for the determination of microRNAs via two-stage signal enhancement. This is attained by combining hairpin (HP) assisted...
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The detection of Fe (III) and ascorbic acid by fluorescence quenching and recovery of carbon dots prepared from coffee waste
Coffee waste-derived carbon dots (C-CDs) that emit blue light were synthesized via hydrothermal process. The synthesized C-CDs have a round shape...
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Signal differentiation models for multiple microRNA detection: a critical review
MicroRNAs (miRNAs) are a class of small, single-stranded non-coding RNAs which have critical functions in various biological processes. Increasing...
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Nucleic acid and nanomaterial-assisted signal-amplified strategies in fluorescent analysis of circulating tumor cells and small extracellular vesicles
As two main types of liquid biopsy markers, both circulating tumor cells (CTCs) and small extracellular vesicles (sEVs) play important roles in the...
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Nucleic Acid Amplification Strategies for Biosensing, Bioimaging, and Biomedicine
Nucleic acidNucleic Acids amplification methods are nucleic acid-assistant signal amplification strategies, which have been widely studied and...
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Engineered CRISPR-Cas systems for the detection and control of antibiotic-resistant infections
Antibiotic resistance is spreading rapidly around the world and seriously impeding efforts to control microbial infections. Although nucleic acid...
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Nucleic Acid Amplification Strategies for In Vitro and In Vivo Metal Ion Detection
Metal ionsMetal ions are critical to many biological, chemical, and environmental processes. In recent years, many nucleic acid-based...
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Theoretical determination of two-photon absorption in biologically relevant pterin derivatives
Given the prevalence of fluorescence spectroscopy in biological systems, and the prevalence of pterin derivatives throughout biological systems,...
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Nicking-enhanced rolling circle amplification for sensitive fluorescent detection of cancer-related microRNAs
In this study, a biosensing system based on nicking-enhanced rolling circle amplification (N-RCA) was proposed for the highly sensitive detection of...
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Surface-Enhanced Raman Spectroscopy for Bioimaging Based on Nucleic Acid Amplification Strategies
Surface-enhanced Raman scattering (SERS) has been widely used on biosensing and bioimaging, especially for nucleic acid analysis. However, some...
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Nucleic Acid Amplification Strategy-Based Electrochemiluminescence Research
Electrochemiluminescence (electrogenerated chemiluminescence, ECL) hasChemiluminescence (CL) been widely used in analytical chemistry due to its...
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An ultrasensitive conformation-dependent colorimetric probe for the detection of mercury(II) using exonuclease III-assisted target recycling and gold nanoparticles
An ultrasensitive conformation-dependent colorimetric assay has been developed for the detection of mercury(II) ions. It is based on the use of...
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Ultrasensitive voltammetric determination of kanamycin using a target-triggered cascade enzymatic recycling couple along with DNAzyme amplification
The authors describe a label-free electrochemical aptasensor for ultrasensitive and highly specific detection of the antibiotic based on cascade...
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Operation planning of energy storage system considering multiperiod energy supplies and demands
The energy storage system (ESS) is recently drawing an increasing attention as an efficient and affordable tool in energy systems. While most...
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Aptamer based electrochemical adenosine triphosphate assay based on a target-induced dendritic DNA nanoassembly
The authors describe an electrochemical strategy for highly sensitive determination of ATP that involves (a) aptamer-based target recognition, (b)...
