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Current Status of Microneedle Array Technology for Therapeutic Delivery: From Bench to Clinic
In recent years, microneedle (MN) patches have emerged as an alternative technology for transdermal delivery of various drugs, therapeutics proteins,...
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Tackling the challenges of develo** microneedle-based electrochemical sensors
Microneedles provide unique advantages in biomedical areas, particularly biosensing, because of their opportunities for minimally invasive and...
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Dissolvable layered microneedle patch containing 5-fluorouracil for localized treatment of oral carcinoma
The matrix-forming microneedle-based drug delivery system has the potential to localize drug dosage to the application site and limit systemic...
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Emerging Application of Nanocelluloses for Microneedle Devices
In quest of an efficient delivery system and for accurate delivery of drug to the ailment site, various researchers focused on development of a...
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Emerging Application of Nanocelluloses for Microneedle Devices
In quest of an efficient delivery system and for accurate delivery of drug to the ailment site, various researchers focused on development of a...
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Yunnan Baiyao-loaded multifunctional microneedle patches for rapid hemostasis and cutaneous wound healing
Microneedle patches have been extensively employed for wound healing, while the lack of rapid hemostasis efficiency and multiple tissue-repair...
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Stainless steel electrochemical capacitive microneedle sensors for multiplexed simultaneous measurement of pH, nitrates, and phosphates
Concerns for agri-food safety and environmental management require development of simple to use and cost- and time-effective multiplex sensors for...
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Microneedle-based nanoporous gold electrochemical sensor for real-time catecholamine detection
Dopamine (DA), epinephrine (EP), and norepinephrine (NEP) are the main catecholamine of clinical interest, as they play crucial roles in the...
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Microneedle delivery system with rapid dissolution and sustained release of bleomycin for the treatment of hemangiomas
Hemangioma of infancy is the most common vascular tumor during infancy and childhood. Despite the proven efficacy of propranolol treatment, certain...
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Locoregional Melanoma Therapy by Tissue Adhesive Microneedle Patch-assisted Trans-tumoral Delivery of Anticancer Drug
Melanoma is one of the most threatening cancers due to its metastatic capacity and its incidence is recently increasing due to ozone depletion and...
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MXenes-integrated microneedle combined with asiaticoside to penetrate the cuticle for treatment of diabetic foot ulcer
Patients with diabetic foot ulcers usually suffer from inefficient epithelisation and angiogenesis accompanied by chronic wound healing. Diabetic...
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Immunotherapy for type 1 diabetes mellitus by adjuvant-free Schistosoma japonicum-egg tip-loaded asymmetric microneedle patch (STAMP)
BackgroundType 1 diabetes mellitus (T1DM) is an autoimmune disease mediated by autoreactive T cells and dominated by Th1 response polarization....
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Modified stainless steel microneedle electrode for polyphenolics detection
This work outlines a simple fabricated microneedle electrode for sensitive and real sample monitoring of plant polyphenolics. The electrode was...
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A novel multifunctional microneedle patch for synergistic photothermal- gas therapy against maxillofacial malignant melanoma and associated skin defects
Considering the high recrudescence and the long-lasting unhealed large-sized wound that affect the aesthetics and cause dysfunction after resection...
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Advances in microneedles for transdermal diagnostics and sensing applications
Microneedles, the miniaturized needles, which can pierce the skin with minimal invasiveness open up new possibilities for constructing personalized...
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Recent advances of microneedles biosensors for plants
As the lack of plants can affect the energy operation of the entire ecosystem, monitoring and improving the health status of plants is crucial....
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Hyaluronic acid-based biodegradable microneedles loaded with epidermal growth factor for treatment of diabetic foot
Pain relief and effective methods of treating patients with diabetic foot wounds have yet to be established. Improved surgical treatment, other than...
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NIR light-activatable dissolving microneedle system for melanoma ablation enabled by a combination of ROS-responsive chemotherapy and phototherapy
BackgroundAs a consequence of the aggressive and recurrent nature of melanoma, repeated, multimodal treatments are often necessary to cure the...
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Recent advancements in the expedition of microneedles: from lab worktops to diagnostic care centers
Microneedle (MN) technology plays a significant role in bioengineering as it allows for minimally invasive exposure to the skin via the non-invasive...
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Microcavity Surfaces for Robust Hot-Water Super-Repellency
This chapter is on continuous microcavity surfaces that display more robust super-repellency to hot water than the discrete microneedle surface. The...