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Selective Schiff base formation via gas-phase ion/ion reactions to enable differentiation of isobaric lipids in imaging mass spectrometry
The separation and identification of lipids in complex mixtures are critical to deciphering their cellular functions. Failure to resolve isobaric...
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Challenges and opportunities for on-line monitoring of chlorine-produced oxidants in seawater using portable membrane-introduction Fourier transform-ion cyclotron resonance mass spectrometry
The present study reports the first evaluation of a MIMS device equipped with a high-resolution Fourier transform-ion cyclotron resonance mass...
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Atmospheric pressure field desorption-trapped ion mobility-mass spectrometry coupling
While field ionization (FI) and field desorption (FD) are established soft vacuum ionization methods in mass spectrometry (MS), the technique of...
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The development of cyclotron-based radiopharmaceuticals: a comprehensive review of 64Cu and 123I-radiolabeled urea-based small molecule PSMA ligands
64 Cu and 123 I are attracting attention in taking up their role in the development and practical use of PSMA-targeting radiopharmaceuticals. The...
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Molecular ion formation on activated field emitters in atmospheric pressure field desorption mass spectrometry
Atmospheric pressure field desorption (APFD) mass spectrometry (MS) has recently been explored as a new contribution to the field of ambient...
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The LARAMED project at INFN-LNL: review of the research activities on medical radionuclides production with the SPES cyclotron
The present work reports the status of the LAboratory of RAdionuclides for MEDicine facility, as part of the Selective Production of Exotic Species...
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Gas-Phase Ion–Ion Reactions for Lipid Identification in Biological Tissue Sections
The unambiguous identification of isobaric (i.e., same nominal mass) and isomeric (i.e., same exact mass) lipids remains a challenging yet vital...
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A spectroscopic test suggests that fragment ion structure annotations in MS/MS libraries are frequently incorrect
Modern untargeted mass spectrometry (MS) analyses quickly detect and resolve thousands of molecular compounds. Although features are readily...
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Direct production of molecular oxygen from carbon dioxide and helium ion collisions
The prebiotic mechanism to produce molecular oxygen (O 2 ) in carbon dioxide (CO 2 )-rich planetary atmospheres is of great importance in understanding...
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Influence of Nitrogen Seeding on the Electron and Ion Behaviors in Helicon Wave Excited Argon Plasma
The effect of nitrogen gas seeding on electron density, electron energy probability functions (EEPFs), ion energy distribution functions (IEDFs) and...
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Application of atmospheric pressure field desorption for the analysis of anionic surfactants in commercial detergents
Recent work has shown that field desorption (FD) and field ionization (FI) using activated field emitters may be performed at atmospheric pressure,...
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Elucidating molecular level impact of peat fire on soil organic matter by laser desorption ionization Fourier transform ion cyclotron resonance mass spectrometry
In this work, laser desorption ionization coupled with Fourier transform ion cyclotron resonance mass spectrometry (LDI–FTICRMS) was used to...
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Applying a risk assessment guided evaluation for verifying comprehensive two-dimensional gas chromatography to analyse complex pharmaceuticals
The reliability of analytical results is critical and indispensable when applied in regulated environments such as the pharmaceutical industry....
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Metal Ion-Induced Changes in the Stability of DNA Duplexes
The thermal stability of DNA duplexes is generally influenced by counter cations such as coexisting metal ions. In addition, duplex stabilization by...
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Metal Ion-Induced Changes in the Stability of DNA Duplexes
The thermal stability of DNA duplexes is generally influenced by counter cations such as coexisting metal ions. In addition, duplex stabilization by...
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Single-Cell Metabolomics with Rapid Determination of Chemical Formulas from Isotopic Fine Structures
Metabolomic measurements can provide functional readouts of cellular states and phenotypes. Here, we present a protocol for single-cell metabolomics...
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Altered prefrontal neurochemistry in the DJ-1 knockout mouse model of Parkinson’s disease: complementary semi-quantitative analyses with in vivo magnetic resonance spectroscopy and MALDI-MSI
In vivo proton magnetic resonance spectroscopy ( 1 H-MRS) and matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) are two...
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Reaction Kinetics and Secondary Organic Aerosol Composition Analysis of 2-Cyclohexen-1-one with NO3 Radicals
Unsaturated ketones are typical oxygenated volatile organic compounds (OVOCs) with high reactivity, and are important precursors in air pollution....
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Specific Features of the Design and Operation of Magnetic Resonance Mass Spectrometers
AbstractsMagnetic resonance mass spectrometers (MRMSs), developed in the second half of the 20th century at the Ioffe Institute, have still possessed...
