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Targeted delivery of organic small-molecule photothermal materials with engineered extracellular vesicles for imaging-guided tumor photothermal therapy
Imaging-guided photothermal therapy (PTT) for cancers recently gathered increasing focus thanks to its precise diagnosis and potent therapeutic...
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Self-assembled amphiphilic NIR-II emissive nano-micelles for imaging-guided photothermal therapy of colorectal cancer
Colorectal cancer (CRC) is one of the major causes of cancer-related mortality worldwide. Most near-infrared (NIR) agents used in clinical CRC...
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Enhancing intracellular mRNA precise imaging-guided photothermal therapy with a nucleic acid-based polydopamine nanoprobe
Despite significant advancements in cancer research, real-time monitoring and effective treatment of cancer through non-invasive techniques remain a...
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Polydopamine Nanoparticle-Incorporated Fluorescent Hydrogel for Fluorescence Imaging-Guided Photothermal Therapy of Cancers
In this study, we report a fluorescent polydopamine nanoparticle-incorporated hydrogel (FPNP-hydrogel) for fluorescence imaging-guided photothermal...
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Mild photothermal/radiation therapy potentiates ferroptosis effect for ablation of breast cancer via MRI/PA imaging guided all-in-one strategy
BackgroundNanotheranostics advances anticancer management by providing therapeutic and diagnostic functions, that combine programmed cell death (PCD)...
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A mitochondria-targeted molecular phototheranostic platform for NIR-II imaging-guided synergistic photothermal/photodynamic/immune therapy
Phototherapy is a conducive and non-invasive strategy for cancer therapy under light irradiation. Inspiringly, fluorescence imaging in the second...
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Kinetically and thermodynamically controlled one-pot growth of gold nanoshells with NIR-II absorption for multimodal imaging-guided photothermal therapy
Since the successful clinical trial of AuroShell for photothermal therapy, there is currently intense interest in develo** gold-based core-shell...
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“All in one” nanoprobe Au-TTF-1 for target FL/CT bioimaging, machine learning technology and imaging-guided photothermal therapy against lung adenocarcinoma
The accurate preoperative diagnosis and tracking of lung adenocarcinoma is hindered by non-targeting and diffusion of dyes used for marking tumors....
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Selenium-integrated conjugated oligomer nanoparticles with high photothermal conversion efficiency for NIR-II imaging-guided cancer phototheranostics in vivo
Second near-infrared (NIR-II) fluorescence imaging in the range of 1000–1700 nm has great prospects for in vivo imaging and theranostics monitoring....
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PLG-g-mPEG Mediated Multifunctional Nanoparticles for Photoacoustic Imaging Guided Combined Chemo/Photothermal Antitumor Therapy
Under laser irradiation, photothermal therapy (PTT) effectively ablates tumors above 50 °C. However, hyperthermia can cause additional damage due to...
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A synergetic strategy of NIR-II squaraine dyes with ultrahigh photothermal conversion efficiency for photothermal therapy
Recent research on photothermal therapy (PTT) has sparked significant interest in the development of new organic photothermal agents (PTAs), ranging...
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A mitochondrion-targeted cyanine agent for NIR-II fluorescence-guided surgery combined with intraoperative photothermal therapy to reduce prostate cancer recurrence
Poorly identified tumor boundaries and nontargeted therapies lead to the high recurrence rates and poor quality of life of prostate cancer patients....
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Cancer cell membrane-coated nanoparticles for bimodal imaging-guided photothermal therapy and docetaxel-enhanced immunotherapy against cancer
BackgroundMono-therapeutic modality has limitations in combating metastatic lesions with complications. Although emerging immunotherapy exhibits...
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A core-shell Au@Cu2-xSe heterogeneous metal nanocomposite for photoacoustic and computed tomography dual-imaging-guided photothermal boosted chemodynamic therapy
Chemodynamic therapy (CDT) has aroused extensive attention for conquering cancers because of its high specificity and low invasiveness. Quick...
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Self-delivery photothermal-boosted-nanobike multi-overcoming immune escape by photothermal/chemical/immune synergistic therapy against HCC
Immune checkpoint inhibitors (ICIs) combined with antiangiogenic therapy have shown encouraging clinical benefits for the treatment of unresectable...
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All-in-one approaches for triple-negative breast cancer therapy: metal-phenolic nanoplatform for MR imaging-guided combinational therapy
BackgroundConventional chemotherapy has poor efficacy in triple-negative breast cancer (TNBC) which is highly heterogeneous and aggressive....
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Rational design of NIR-II molecule-engineered nanoplatform for preoperative downstaging and imaging-guided surgery of orthotopic hepatic tumor
Orthotopic advanced hepatic tumor resection without precise location and preoperative downstaging may cause clinical postoperative recurrence and...
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Near-infrared photodynamic and photothermal co-therapy based on organic small molecular dyes
Near-infrared (NIR) organic small molecule dyes (OSMDs) are effective photothermal agents for photothermal therapy (PTT) due to their advantages of...
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Recent Advances in Bio-Inspired Versatile Polydopamine Platforms for “Smart” Cancer Photothermal Therapy
Although photothermal therapy (PTT) has been developed for fighting cancers, the degradative, toxic, and metabolic nature of photothermal conversion...
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White-light-driven fluorescence switch for super-resolution imaging guided photodynamic and photoacid therapy
Photocaged fluorophores with photoactivatable characteristics presented important applications in imaging the biological structures and processes....