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Analysis of metabolites in human gut: illuminating the design of gut-targeted drugs
Gut-targeted drugs provide a new drug modality besides that of oral, systemic molecules, that could tap into the growing knowledge of gut metabolites...
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Targeting the human gut microbiome with small-molecule inhibitors
The human gut microbiome is a complex microbial community that is strongly linked to both host health and disease. However, the detailed molecular...
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Exploring the gut microbiome: probiotics, prebiotics, synbiotics, and postbiotics as key players in human health and disease improvement
The human gut microbiome accompanies us from birth, and it is developed and matured by diet, lifestyle, and environmental factors. During aging, the...
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Machine learning for data integration in human gut microbiome
Recent studies have demonstrated that gut microbiota plays critical roles in various human diseases. High-throughput technology has been widely...
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Review of the Health Benefits of Cereals and Pseudocereals on Human Gut Microbiota
Cereals and pseudocereal crops are mostly used for human consumption in the world. They possess various beneficial characteristics and can be...
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Beneficial effects of GABA-producing potential probiotic Limosilactobacillus fermentum L18 of human origin on intestinal permeability and human gut microbiota
BackgroundGamma-aminobutyric acid (GABA) is a non-protein amino acid with neuroinhibitory, antidiabetic, and antihypertensive properties and is used...
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The functional roles of short chain fatty acids as postbiotics in human gut: future perspectives
The significance of gut microbiome and their metabolites (postbiotics) on human health could be a promising approach to treat various diseases that...
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Resistant starch utilization by Bifidobacterium, the beneficial human gut bacteria
Resistant starch (RS) reaches the large intestine largely intact, where it is fermented by the gut microbiota, resulting in the production of...
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Identification of conserved genomic signatures specific to Bifidobacterium species colonising the human gut
Bifidobacterium species are known for their ability to inhabit various habitats and are often regarded as the first colonisers of the human gut. In...
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Dietary mung bean as promising food for human health: gut microbiota modulation and insight into factors, regulation, mechanisms and therapeutics—an update
Plant-based functional foods have gained wider attention in current scenario with mung bean harboring several bioactive compounds with promising gut...
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Amorphous silica nanoparticles and the human gut microbiota: a relationship with multiple implications
Amorphous silica nanoparticles (ASNP) are among the nanomaterials that are produced in large quantities. ASNP have been present for a long time in...
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Comparison of the relative impacts of acute consumption of an inulin-enriched diet, milk kefir or a commercial probiotic product on the human gut microbiome and metabolome
It has been established that the human gut microbiota is central to health, and, consequently, there has been a growing desire to positively modulate...
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Detection of typical indigenous gut bacteria related to kanpyo Lagenaria siceraria var. hispida powder in murine caecum and human faecal cultures
Kanpyo (KP) is an edible dried product produced by peeling the fruit of the gourd Lagenaria siceraria var . hispida ; it is used in the traditional...
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Association of human gut microbiota composition and metabolic functions with Ficus hirta Vahl dietary supplementation
Ficus hirta Vahl (FHV), a traditional herbal ingredient of the tonic diet, receives increasing popularity in southern China. However, it is largely...
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Sulfated glycan recognition by carbohydrate sulfatases of the human gut microbiota
Sulfated glycans are ubiquitous nutrient sources for microbial communities that have coevolved with eukaryotic hosts. Bacteria metabolize sulfated...
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Metabolism of a hybrid algal galactan by members of the human gut microbiome
Native porphyran is a hybrid of porphryan and agarose. As a common element of edible seaweed, this algal galactan is a frequent component of the...
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Gamma-aminobutyric acid as a potential postbiotic mediator in the gut–brain axis
Gamma-aminobutyric acid (GABA) plays a crucial role in the central nervous system as an inhibitory neurotransmitter. Imbalances of this...
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The Impact of Gut Microbiota on Mental Health
This chapter delves deeply into the intricate relationship between human health and the gut microbiota, with a specific emphasis on the microbiome’s...
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Role of Probiotics in Gut Micro-flora
Human gastro-intestinal tract is inhabited by the most diverse cluster of microorganisms known as gut micro-flora and actively partake in numerous...
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Sample Processing for Metaproteomic Analysis of Human Gut Microbiota
Human gut microbiota can be studied through the characterization of microorganisms present in feces. Metaproteomics has arisen as a good approach to...