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Quantification of Mycophenolic Acid in Plasma by High Performance Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Mycophenolate mofetil (MMF) and sodium mycophenolate are commonly prescribed immunosuppressive drugs for patients who have undergone solid organ...
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Turbulent Flow Liquid Chromatography-Tandem Mass Spectrometry Methods for Antiepileptic Drug Quantitation in Serum
Epilepsy is characterized by abnormal electrical discharges in the brain that result in unprovoked seizures. Pharmacotherapy with antiepileptic drugs...
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Biomonitoring urinary organophosphorus flame retardant metabolites by liquid–liquid extraction and ultra-high performance liquid chromatography-tandem mass spectrometry and their association with oxidative stress
Organophosphate flame retardants (OPFRs) are widely used as substitutes for traditional brominated flame retardants, necessitating a reliable and...
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Quantification of Olanzapine by Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Olanzapine (Zyprexa™) is indicated for the treatment of schizophrenia and bipolar disorder. Olanzapine is metabolized to inactive metabolites;...
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Determination of Steroid Hormones in Human Saliva by High-Performance Liquid Chromatography with Tandem Mass Spectrometry Detection
AbstractA method is developed for the simultaneous determination of steroid hormones of various classes (androgens, progestins, and glucocorticoids)...
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Analysis of Serum Estrogens Using High-Performance Liquid Chromatography–Tandem Mass Spectrometry Coupled to Differential Ion Mobility Spectrometry
AbstractA new quantification method is proposed for the determination of serum estrone (E1), estradiol (E2), and estriol (E3) based on...
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Mass Spectrometry with High-Performance Liquid Chromatography
Mass spectrometry (MS) is an analytical technique that provides information about the molecular weight and chemical characteristics of a compound....
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Quantification of Clofarabine and Fludarabine in Plasma by High-Performance Liquid Chromatography-Tandem Mass Spectrometry
Allogeneic hematopoietic cell transplantation (allo-HCT) is a potentially curative therapeutic treatment for many patients with high-risk hematologic...
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Liquid Chromatography-Tandem Mass Spectrometry-Based Therapeutic Monitoring of Plasma Atovaquone Concentrations in Pediatric Patients
Atovaquone is an FDA-approved antiparasitic and antifungal therapeutic that is currently used as a prophylactic agent to prevent Pneumocystis carinii...
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A Novel Strategy for Screening of Secondary Metabolites in Ginkgo biloba Leaves by Ultra-Performance Liquid Chromatography–Tandem Information Dependent Acquisition Mass Spectrometry
AbstractA novel and simple strategy was proposed for the screening of secondary metabolites in Ginkgo biloba leaves. The information dependent...
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Detection of 41 Drugs and Metabolites in Urine with Internal Hydrolysis Control by Liquid Chromatography-Tandem Mass Spectrometry
Regular monitoring of pain management and substance use disorder patients through urine drug screening is important for assessing patient compliance...
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Determination of 9 Biological Amines and 2 Organic Amines in Fish Meat by Precolumn Derivatization Liquid Chromatography-Tandem Mass Spectrometry Based on Hinsberg Reaction
Multiple studies have demonstrated the harmful effects of consuming high levels of biogenic amines (BAs) and organic amines (OAs), underscoring the...
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A Liquid Chromatography-Tandem Mass Spectrometry Assay for Quantification of Ethyl Glucuronide and Ethyl Sulfate in Urine
Ethyl glucuronide and ethyl sulfate emerged as the biomarkers of choice for detection of ethanol use as the required sample is urine, enabling easy...
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Quantification of Amino Acids in Plasma by High-Performance Liquid Chromatography–Tandem Mass Spectrometry (LC–MS/MS)
For the extraction and measurement of plasma amino acids using LC/ESI–MS/MS technology, a straightforward and dependable approach has been...
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Drug Screening of 49 Compounds by Liquid Chromatography-Tandem Mass Spectrometry in Saliva
In recent years, the use of oral fluid as a testing matrix for drug analysis has become increasingly popular due to its benefits, such as a...
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High-pH mobile phase in reversed-phase liquid chromatography-tandem mass spectrometry to improve the separation efficiency of aminoglycoside isomers
In chromatography, the use of extreme conditions can often lead to unique separation selectivity. In this study, a highly basic mobile phase...
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Quantification of Gabapentin, Lacosamide, Perampanel, Pregabalin, Rufinamide, and Vigabatrin in Serum Using Liquid Chromatography-Tandem Mass Spectrometry
Antiepileptic drugs (AEDs) have been used to control epilepsy. More than 17 new AEDs, including gabapentin (GPN), lacosamide (LCM), perampanel (PER),...
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Multiresidue Determination of Fungicides in Wine by Solvent Demulsification-Dispersive Liquid-Liquid Microextraction and Ultra-High Performance Liquid Chromatography–Tandem Mass Spectrometry
Fungicides are applied from plant development to grape production, transport, and storage. Even after fruit processing, residues of these compounds...
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Liquid Chromatography-Tandem Mass Spectrometry Method for the Quantification of Plasma Busulfan
Busulfan is an alkylating agent and functions as a myeloablative and anti-leukemic chemotherapy drug. It is widely used with cyclophosphamide for...
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Determination of Treosulfan and Fludarabine in Plasma by Turbulent Flow Liquid Chromatography-Tandem Mass Spectrometry (TFLC-MS/MS)
Treosulfan is a structural analog of the alkylating agent busulfan which has been shown in clinical trials to exhibit comparable myeloablative...