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Anti-obesity potential of bioactive guided fractions of Annona squamosa linn. leaves extract: a combination of in-vitro, in-vivo and in-silico studies along with profiling of lead compounds by HPTLC MS-MSn method
The antiobesity potential of bioactive fractions derived from Annona squamosa was approached using a combination of in vitro, in silico and in-vivo...
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Identification, Validation and Standardization of Bioactive Molecules Using UPLC/MS-QToF, UHPLC and HPTLC in Divya-Denguenil-Vati: A Penta-Herbal Formulation for Dengue Fever
For the last fifty years, Dengue has been one of the most common mosquito-borne arboviral infections which has spread over the tropical and...
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A validated HPTLC method for quantification of cordifolioside A, 20-β-hydroxyecdysone and columbin with HPTLC–ESI–MS/MS characterization in stems of Tinospora cordifolia
The objective of the present work was to develop a simple, specific, and fast high-performance thin-layer chromatographic (HPTLC) method to identify...
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Inherent stability testing of empagliflozin in the presence of metformin HCl by HPTLC and characterization of degradation products of empagliflozin by LC–ESI–QTOF–MS/MS
A successful attempt has been made to develop and validate a stability-indicating high-performance thin-layer chromatography (HPTLC) method for the...
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HPTLC–MS method for the determination of benzodiazepines in urine samples
Misuse and abuse of prescription drugs has become a global health problem in the last few years as the illicit drug cartels have grown exponentially....
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Validation of an analytical method for the detection of ephedrine and its analogues in forensic samples using HPTLC–MS
Drug abuse is a global menace in the society. Strict measures are planned and effectuated to dismantle this crime yet a large number of cases of...
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High-performance thin-layer chromatography‒multi-stage mass spectrometry methods for analyses of bee pollen botanically originating from sweet chestnut (Castanea sativa Mill.)
High-performance thin-layer chromatographic (HPTLC) silica gel and amino plates in combination with develo** solvents containing formic and acetic...
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Phytochemical analysis, isolation and quantitative estimation of karan** in the stem bark of Millettia pinnata by a validated high-performance thin-layer chromatography method
Millettia pinnata ( Fabaceae ) is a multipurpose legume tree native to Southeast Asia. In this study, the methanolic extract of M. pinnata stem bark...
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Comparison of palynological method and chromatographic analysis combined with chemometrics to identify botanical origin of propolis
There has been a growing trend in consumer’s preferences for food supplements containing propolis due to having a wide range of phenolic compounds to...
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Validated chromatographic methods for determination of teriflunomide and investigation of its intrinsic stability
Two rapid, precise, and sensitive stability-indicating high performance chromatographic methods for the measurement of Teriflunomide in its...
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Lipidomic studies based on high-performance thin-layer chromatography
The last triennium has shown a significant contribution of high-performance thin-layer chromatography (HPTLC) to lipidomics. HPTLC separation in...
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Agar-free high-performance thin-layer chromatography–bioautography method for the qualitative estimation of α-amylase inhibitor in Syzygium cumini seed extract and formulation
Quality control of herbal medicines is an important stage in generating effective and safe herbal remedies. A unique high-throughput approach for...
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Combination of high-performance thin-layer chromatography and liquid chromatography–quadrupole time-of-flight–tandem mass spectrometry analysis: a promising analytical tool for discrimination between oleo-gum resin of raw and purified Commiphora wightii
Guggulu ( Commiphora wightii oleo-gum resin) is exported in more than 42 countries including developed countries like the United Kingdom and the...
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Development of a high-performance thin-layer chromatography-based method for targeted glycerolipidome profiling of microalgae
The conditionally essential very-long-chain polyunsaturated fatty acids (VLC-PUFAs), such as eicosapentaenoic acid (EPA, C20:5 n-3), play a vital...
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Development and validation of a high-performance thin-layer chromatography‒densitometric method and mass spectroscopy profiling for the determination of bioactive phytosterol from Manilkara zapota L. P. Royen leaves and correlating its antioxidant and antiinflammatory potential
A simple, reliable high-performance thin-layer chromatography (HPTLC)‒densitometry method was developed and validated for the quantification of...
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Acetylcholinesterase (ACHE) and α-Glucosidase Inhibitory Assay by Effect-Directed Analysis on High Performance Thin-Layer Chromatography Coupled to Mass Spectrometry
The traditional study of natural sources bioactivity is based on the evaluation of diverse biological activities like antioxidant or enzymes...
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Recent findings by high-performance thin-layer chromatographic separation for a comprehensive analysis of Withania somnifera by densitometry and mass spectrometry: an assessment to quality and adulteration
AbstractWithania somnifera (L.) Dunal (WS), also known as Ashwagandha, is an Indian herb classified as Rasayana in Ayurveda owing to its...
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Identification and quantification of cannabinol as a biomarker for local hemp retting in an ancient sedimentary record by HPTLC-ESI-MS
Cannabis products have been used in various fields of everyday life for many centuries, and applications in folk medicine and textile production have...
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Screening of orange peel waste on valuable compounds by gradient multiple development diode-array high-performance thin-layer chromatography
High-performance thin-layer chromatography (HPTLC), as the modern form of TLC (thin-layer chromatography), is suitable for detecting pharmaceutically...
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Validated simultaneous high-performance thin-layer chromatography‒mass spectrometry method for analysis of citalopram prochlorperazine, midazolam, and chlorodiazepoxide in urine for forensic analysis
Drug breakthroughs and development have been a great blessing to mankind. Problem arises when these are used in non-medical context such as use for...
