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1. Hepatic glutamine synthetase controls N⁵-methylglutamine in homeostasis and cancer

   Glutamine synthetase (GS) activity is conserved from prokaryotes to humans, where the ATP-dependent production of glutamine from glutamate and...

   Victor H. Villar, Maria Francesca Allega, ... Saverio Tardito in Nature Chemical Biology

   Article Open access 24 October 2022
   

2. A C-terminal glutamine recognition mechanism revealed by E3 ligase TRIM7 structures

   The E3 ligase TRIM7 has emerged as a critical player in viral infection and pathogenesis. However, the mechanism governing the TRIM7–substrate...

   **ao Liang, Jun **ao, ... Heng Zhang in Nature Chemical Biology

   Article 18 August 2022
   

3. CAFs targeted ultrasound-responsive nanodroplets loaded V9302 and GLULsiRNA to inhibit melanoma growth via glutamine metabolic reprogramming and tumor microenvironment remodeling

   Despite rapid advances in metabolic therapies over the past decade, their efficacy in melanoma has been modest, largely due to the interaction...

   Chen Ai, **ao Sun, ... Jie Li in Journal of Nanobiotechnology

   Article Open access 08 July 2023
   

4. Cerium ions immobilized magnetic graphite nitride decorated with L-Alanyl-L-Glutamine as new chelator for enrichment of phosphopeptides

   Cerium ions immobilized magnetic graphite nitride material have been prepared using L-Alanyl-L-Glutamine as the new chelator. The resulting Fe ₃ O ₄ /g-C ₃ N...

   Dandan Jiang, Siyu Wu, ... **ghai Liu in Microchimica Acta

   Article 26 October 2023
   

5. Simultaneous glutamine metabolism and PD-L1 inhibition to enhance suppression of triple-negative breast cancer

   Blockade of programmed cell death 1 ligand (PD-L1) has been used to treat triple-negative breast cancer (TNBC), and various strategies are under...

   Yuxia Tang, Siqi Wang, ... Shouju Wang in Journal of Nanobiotechnology

   Article Open access 06 May 2022
   

6. Glutamine involvement in nitrogen regulation of cellulase production in fungi

   Background

   Cellulase synthesized by fungi can environment-friendly and sustainably degrades cellulose to fermentable sugars for producing cellulosic...

   Ai-** Pang, Funing Zhang, ... Fengming Lin in Biotechnology for Biofuels

   Article Open access 13 October 2021
   

7. Circ_0001093 promotes glutamine metabolism and cancer progression of esophageal squamous cell carcinoma by targeting miR-579-3p/glutaminase axis

   Increasing studies indicate that circular RNAs (circRNAs) play critical roles in tumor metabolism of multiple cancers. However, the contribution of...

   Cui-juan Qian, Yi-yang Tong, ... Jun Yao in Journal of Bioenergetics and Biomembranes

   Article 23 March 2022
   

8. Trigger of apoptosis in human liver cancer cell line (HepG2) by titanium dioxide nanoparticles functionalized by glutamine and conjugated with thiosemicarbazone

   The incidence of liver cancer, the third cause of cancer-associated death, has been growing, worldwide. The increasing trend of liver cancer...

   Shahrzad Sadat Shahmoradi, Ali Salehzadeh, ... Hadi Habibollahi in 3 Biotech

   Article 16 May 2023
   

9. Effects of oral cystine and glutamine on exercise-induced changes in gastrointestinal permeability and damage markers in young men

   Purpose

   Although acute prolonged strenuous exercise has been shown to increase markers of gastrointestinal permeability and damage, little is known...

   Yusei Tataka, Miki Haramura, ... Masashi Miyashita in European Journal of Nutrition

   Article Open access 01 February 2022
   

10. Glutamine and Asparagine in Nutritional Products

    Glutamine and asparagine in enteral therapeutic nutritional products, and in the milk, casein, soy, and whey protein ingredients with which they were...

    Paul W. Johns, Steven R. Hertzler in Food Analytical Methods

    Article 03 March 2021
    

11. Semisynthesis of Glutamine-Methylated Proteins Enabled by Genetic Code Expansion

    Gln methylation is a newly identified histone mark and mediates ribosomal biogenesis. Site-specifically Gln-methylated proteins are valuable tools to...

    Weimin Xuan, **aochen Yang in Genetically Incorporated Non-Canonical Amino Acids

    Protocol 2023
    

12. Development of a modified serum-free medium for Vero cell cultures: effects of protein hydrolysates, l-glutamine and SITE liquid media supplement on cell growth

    Vero cells have been widely used in the viral vaccine production due to the recommendation of the World Health Organization regarding its safety and...

    Manoch Posung, Duanthanorm Promkhatkaew, ... Anan Tongta in Cytotechnology

    Article 11 August 2021
    

13. Thermodynamics of the Formation of Complexes of Gd³⁺ and Ho³⁺ with L-Glutamine in Aqueous Solutions

    Abstract

    The enthalpies of complexation of L-glutamine with Gd ³⁺ and Ho ³⁺ are determined calorimetrically at 298.15 K and ionic strength of 0.5 (KNO ₃ )...

    A. I. Lytkin, O. N. Krutova, ... E. D. Krutova in Russian Journal of Physical Chemistry A

    Article 01 January 2021

14. Poly(glutamine) film-coated carbon nanotube paste electrode for the determination of curcumin with vanillin: an electroanalytical approach

    Abstract

    Poly(glutamine) film-modified carbon nanotube paste electrode (PGAMCNTPE) was prepared through the electropolymerization technique. The...

    Girish Tigari, J. G. Manjunatha in Monatshefte für Chemie - Chemical Monthly

    Article 05 November 2020
    

15. Enantioanalysis of glutamine—a key factor in establishing the metabolomics process in gastric cancer

    Gastric cancer is the second leading cause of death in the world. Early detection will facilitate early treatment and full recovery of the patients....

    Raluca-Ioana Stefan-van Staden, Ruxandra-Maria Ilie-Mihai, ... Stela Pruneanu in Analytical and Bioanalytical Chemistry

    Article 18 March 2020
    

16. Metabolic engineering of Escherichia coli for efficient production of l-alanyl-l-glutamine

    Background

    l -Alanyl- l -glutamine (AQ) is a functional dipeptide with high water solubility, good thermal stability and high bioavailability. It is...

    Jiangming Zhu, Wei Yang, ... Yong Tao in Microbial Cell Factories

    Article Open access 11 June 2020
    

17. Interplay among the “flip**” glutamine, a conserved phenylalanine, water and hydrogen bonds within a blue-light sensing LOV domain

    In this work we exploited time-resolved photoacoustics (PA) and molecular dynamics (MD) simulations to investigate the function of a conserved...

    Eugenia Polverini, Florian Karl Schackert, Aba Losi in Photochemical & Photobiological Sciences

    Article 01 July 2020

18. Synthesis of polyaniline microtubes/Pt reduced N-graphene oxide in the presence of L-glutamine for the detection of Hg²⁺

    Abstract

    We report the synthesis and characterization of polyaniline microtubes /Pt reduced N-graphene oxide (PAn MTs Pt N-rGO) nanocomposites in the...

    M. R. Mahmoudian, W. J. Basirun, ... Y. Alias in Journal of Applied Electrochemistry

    Article 26 September 2020
    

19. Therapeutic Benefits of Tuna Oil by In Vitro and In Vivo Studies Using a Rat Model of Acetic Acid-Induced Ulcerative Colitis

    Ulcerative colitis (UC), an inflammation of the colon lining, represents the main form of inflammatory bowel disease IBD. Nutritional therapy is...

    Abla Bouhend, Soumia Keddari, ... Mohamed Bououdina in Applied Biochemistry and Biotechnology

    Article 03 October 2023
    

20. Biochemical Markers of Tumor Cell Sensitivity to L-Asparaginase

    Abstract

    L-asparaginase, which hydrolyzes asparagine and, to a lesser extent, glutamine, initially used to treat acute lymphoblastic leukemia and...

    I. A. Kislyak, V. S. Pokrovsky in Biochemistry (Moscow), Supplement Series B: Biomedical Chemistry

    Article 01 September 2023