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Ginkgolide B Suppresses TPA-induced Metastatic Potential in MCF-7 Human Breast Cancer Cells by Inhibiting MAPK/AP-1 Signaling
Ginkgolide B (GKB) is a natural terpenoid lactone found in leaves of Ginkgo biloba and has antioxidative, anti-inflammatory, and anti-tumor...
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Protective Effects of Ginkgolide on a Cellular Model of Alzheimer’s Disease via Suppression of the NF-κB Signaling Pathway
NF-κB signaling has been reported to play a key regulatory role in the pathogenesis of Alzheimer’s disease (AD). The purpose of this study is to...
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A Novel Strategy for Screening of Secondary Metabolites in Ginkgo biloba Leaves by Ultra-Performance Liquid Chromatography–Tandem Information Dependent Acquisition Mass Spectrometry
AbstractA novel and simple strategy was proposed for the screening of secondary metabolites in Ginkgo biloba leaves. The information dependent...
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CB1 as a novel target for Ginkgo biloba’s terpene trilactone for controlling chemotherapy-induced peripheral neuropathy (CIPN)
The application of antineoplastic chemotherapeutic agents causes a common side effect known as chemotherapy-induced peripheral neuropathy (CIPN) that...
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Exploring the multifaceted role of ginkgolides and bilobalide from Ginkgo biloba in mitigating metabolic disorders
The ancient Ginkgo biloba tree grows across various regions, with distinctive leaves emitting a unique fragrance. Its extract contains flavonoids,...
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Profiling of phenolic acids, flavonoids, terpenoids, and steroid derivatives in coconut (Cocos nucifera L.) haustorium
Coconut haustorium (CH) is formed inside coconut shell during coconut germination. This study aimed to investigate the compositions and contents of...
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Simultaneous Determination of Multiple Components in **shui Huanxian Granules by UPLC–Orbitrap Fusion MS
**shui Huanxian granules (JSHX) is a clinical Chinese medicine formula used for the treatment of pulmonary fibrosis (PF). In this study, an accurate...
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Evaluation of the Polyphenol Composition and Acetylcholinesterase Inhibitory Activity of Ginkgo Biloba Leaf Extracts Produced in Subcritical Water
AbstractGinkgo biloba (GB) leaf extracts are obtained in subcritical water (SBW) in the temperature range 100–200°C and studied for the first time in...
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Effect of Cinnamon on the Treatment of Alzheimer’s Disease
Alzheimer’s disease (AD) is the most common dementia disorder worldwide. At present, there are no effective treatment strategies to improve or... -
Plant-Based Bioactive Components: Phytochemicals: A Review
Therapeutic potential of medicinal plants goes back thousands of years, and they will continue to be significant in the discovery of novel drug lead... -
An Introduction to Specialized Metabolites from Plants, Their Biological and Ecological Roles, and Biotechnological Interventions to Improve the Production
Plants obtain their energy-producing carbohydrates from photosynthesis, which in turn are diverted into various primary and secondary metabolites.... -
Synthesis of 2-hexyl-5-ethylfuran-3-sulfonic acid (HEFS) – natural antithrombosis agent from Eisenia earthworms
A total synthesis of 2-hexyl-5-ethylfuran-3-sulfonic acid (HEFS) is reported. HEFS is an important natural product isolated as a major metabolite...
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Neurotrophic Natural Products
Neurotrophins (NGF, BDNF, NT3, NT4) can decrease cell death, induce differentiation, as well as sustain the structure and function of neurons, which... -
Herbal-Infused Honey vis-à-vis Human Health
Honey, a nutritious viscous liquid produced by the honeybees (Apis mellifera) has been an important ingredient of many Ayurvedic traditional... -
HPLC and HPLC–MS for Qualitative and Quantitative Analysis of Chinese Medicines
Active compounds derived from Chinese medicines (CMs) have already illustrated immense therapeutic potential over an array of different diseases, and... -
Plant Secondary Metabolites as a Source of New Drugs
An increasing number of new pathogens, the emergence of multidrug drug-resistant (MDR) and extremely drug-resistant (XDR) bacterial and fungal... -
Comparison of phytochemical composition of Ginkgo biloba extracts using a combination of non-targeted and targeted analytical approaches
Ginkgo biloba extract (GbE) is a dietary supplement derived from an ethanolic extract of Ginkgo biloba leaves. Unfinished bulk GbE is used to make...
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Bio-Specific Extraction/Receptor Fishing for Screening of Active Components in Chinese Medicines
In this chapter, the principles and processes of bio-specific extraction/receptor fishing, such as equilibrium dialysis, centrifugation, and... -
A nontargeted approach to determine the authenticity of Ginkgo biloba L. plant materials and dried leaf extracts by liquid chromatography-high-resolution mass spectrometry (LC-HRMS) and chemometrics
The lack of stringent regulations regarding raw materials for herbal supplements used for medicinal purposes has been a constant challenge in the...