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Advances in testing for sample manipulation in clinical and forensic toxicology—part B: hair samples
As a continuation of part A, focusing on advances in testing for sample manipulation of urine samples in clinical and forensic toxicology, part B of...
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Advances in testing for sample manipulation in clinical and forensic toxicology - Part A: urine samples
In many countries, adherence testing is used to monitor consumption behavior or to prove abstinence. Urine and hair are most commonly used, although...
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Development of an innovative analytical method for forensic detection of cocaine, antidepressants, and metabolites in postmortem blood using magnetic nanoparticles
Cocaine and antidepressants rank high globally in substance consumption, emphasizing their impact on public health. The determination of these...
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Spectroscopy as a useful tool for the identification of changes with time in post-mortem vitreous humor for forensic toxicology purposes
Vitreous humor (VH) is an alternative biological matrix with a great advantage of longer availability for analysis due to the lack of many enzymes....
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Analysis of Forensic Trace Evidence
Forensic science is a tool of the enforcement of laws and regulations, improving public safety and hel** to solve cases to policemen. This field... -
Mass Spectrometry in Clinical Laboratory: Applications in Therapeutic Drug Monitoring and Toxicology
Mass spectrometry (MS) coupled with liquid chromatography (LC) or gas chromatography (GC) has been proven to be a powerful platform in research and... -
Hyphenated high-resolution mass spectrometry—the “all-in-one” device in analytical toxicology?
This trend article reviews papers with hyphenated high-resolution mass spectrometry (HRMS) approaches applied in analytical toxicology, particularly...
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Molecularly imprinted polymers as a selective sorbent for forensic applications in biological samples—a review
Molecularly imprinted polymers (MIP) consist of a molecular recognition technology with applicability in different areas, including forensic...
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Development of a rapid-fire drug screening method by probe electrospray ionization tandem mass spectrometry for human urine (RaDPi-U)
Drug screening tests are mandatory in the search for drugs in forensic biological samples, and immunological methods and mass spectrometry (e.g., gas...
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Improvements in identification and quantitation of alkylated PAHs and forensic ratio sourcing
Parent and alkylated polycyclic aromatic hydrocarbons (PAHs) are present in a number of different sources in varying proportions depending on the...
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Unveiling the Power of Nanomaterials in the Area of Forensics
Forensic science has observed significant advancements over the years which has revolutionized the way investigators collect evidence, interpret and... -
Development and validation of a method for analysis of 25 cannabinoids in oral fluid and exhaled breath condensate
Currently, there is a significant demand in forensic toxicology for biomarkers of cannabis exposure that, unlike ∆ 9 -tetrahydrocannabinol, can...
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Spectral and theoretical analysis of derivatives of 1,2,3,3-tetramethyl-3H-indolium iodide (TMI), a highly selective derivatization reagent of cyanide, and their utility for the analysis of cyanide concentrations in beverages
We develop a specific derivatization gas chromatography–mass spectrometry (GC–MS) method for cyanide using 1,2,3,3-tetramethyl-3 H -indium iodide as...
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Detection, chemical analysis, and pharmacological characterization of dipyanone and other new synthetic opioids related to prescription drugs
The emergence of structurally diverse new synthetic opioids (NSOs) has caused the opioid crisis to spiral to new depths. Little information is...
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Simultaneous determination of 12 illicit drugs in hair sample by the nano-titania-modified covalent organic frameworks (NTM-COFs) on-line pass-through cleanup followed by UPLC-MS/MS
An effective analytical method using NTM-COFs on-line pass-through cleanup method and ultra-performance liquid chromatography-tandem mass...
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Application of Planar Chromatography in Pharmaceutical, Clinical, and Toxicological Analysis
Many analytical techniques are used in bioanalysis; among them liquid chromatographic techniques belong to very popular ones. However planar liquid... -
Application of Planar Chromatography in Pharmaceutical, Clinical, and Toxicological Analysis
Many analytical techniques are used in bioanalysis; among them liquid chromatographic techniques belong to very popular ones. However planar liquid... -
Untargeted High-Resolution Mass Spectrometry for Detection of Natural Products and Confiscated Powders and Pills
Drug testing for clinical toxicology purposes is difficult given the variety of drugs and substances that can be abused. High-resolution mass... -
Rapid Simultaneous Determination of Cyanide, Azide, and Ethanol in Whole Blood Using Headspace Gas Chromatography-Mass Spectrometry
The rapid detection and quantification of toxic substances and alcohol in biological specimens stand as imperative tasks, particularly in instances...
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Sample preparation of bone tissue for MALDI-MSI for forensic and (pre)clinical applications
In the past decades, matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) has been applied to a broad range of...