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An economical and practical procedure of favipiravir synthesis for the treatment of Covid-19
Favipiravir is a wide-spectrum antiviral generic drug that has received large attention during the recent COVID-19 pandemic. While there are...
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Spectrophotometric determination of favipiravir in presence of its acid hydrolysis product
Favipiravir (FAV) has been approved as an antiviral drug used in pandemic corona virus to treat covid-19. It has an amide moiety susceptible to...
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Adjusted green spectrophotometric determination of favipiravir and remdesivir in pharmaceutical form and spiked human plasma sample using different chemometric supported models
The environmentally friendly design of analytical methods is gaining interest in pharmaceutical analysis to reduce hazardous environmental impacts...
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Green chemometric-assisted UV-spectrophotometric methods for the determination of favipiravir, cefixime and moxifloxacin hydrochloride as an effective therapeutic combination for COVID-19; application in pharmaceutical form and spiked human plasma
As pharmaceutical analysis progresses towards environmental sustainability, there is a growing need to enhance the safety and health conditions for...
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A highly sensitive and green electroanalytical method for the determination of favipiravir in pharmaceutical and biological fluids
BackgroundFavipiravir is currently used for the treatment of coronavirus disease-2019 (COVID-19).
ObjectiveA highly sensitive and eco-friendly...
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Quantitative analysis of two COVID-19 antiviral agents, favipiravir and remdesivir, in spiked human plasma using spectrophotometric methods; greenness evaluation
Favipiravir and remdesivir have been included in the COVID-19 treatment guidelines panel of several countries. The main objective of the current work...
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Metal oxide nanocage as drug delivery systems for Favipiravir, as an effective drug for the treatment of COVID-19: a computational study
This paper is a summary of research that looks at the potential of fullerene-like (MO) 12 nanoclusters (NCs) in drug-carrying systems using density...
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Core–shell nanocomposite of flower-like molybdenum disulfide nanospheres and molecularly imprinted polymers for electrochemical detection of anti COVID-19 drug favipiravir in biological samples
A novel electrochemical sensor is reported for the detection of the antiviral drug favipiravir based on the core–shell nanocomposite of flower-like...
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Favipiravir: insight into the crystal structure, Hirshfeld surface analysis and computational study
In this work we report structural and computational studies of favipiravir, which is now used as a drug for COVID-19 treatment. The molecule is...
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The application of multi-walled carbon nanotubes modified pencil graphite electrode for voltammetric determination of favipiravir used in COVID-19 treatment
This study describes the first application of an improved procedure on a pencil graphite electrode decorated with functionalized multi-walled carbon...
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The anti-COVID-19 drug Favipiravir: Degradation, Method development, Validation, NMR/LC–MS characterization, and In-vitro safety evaluation
It is critical to characterize the degradation products of therapeutic drugs to determine their safety as these degradation products may possess...
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Voltammetric sensor based on bimetallic nanocomposite for determination of favipiravir as an antiviral drug
A novel and sensitive voltammetric nanosensor was developed for the first time for trace level monitoring of favipiravir based on gold/silver...
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Interactions between favipiravir and a BNC cage towards drug delivery applications
Electronic structure analysis of bimolecular formation of favipiravir (Fav) and a representative model of boron-nitrogen-carbon (BNC) cage was...
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Model of the RNA Polymerase Complex of the SARS-CoV-2 Virus with Favipiravir
AbstractA model of a multidomain complex is constructed using molecular modeling methods to explain the mechanism of the inhibitory effect of...
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The supramolecularly complexes of calix[4]arene derivatives toward favipiravir antiviral drug (used to treatment of COVID-19): a DFT study on the geometry optimization, electronic structure and infrared spectroscopy of adsorption and sensing
While the world is in search of a vaccine that can cure COVID-19 disease, favipiravir is the most commonly used antiviral drug in the treatment of...
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A dispersion-corrected DFT calculation on encapsulation of favipiravir drug used as antiviral against COVID-19 into carbon-, boron-, and aluminum-nitride nanotubes for optimal drug delivery systems combined with molecular docking simulations
Favipiravir (FAV) (6-fluoro-3-oxo-3,4-dihydropyrazine-2-carboxamide) is one of the most effective antiviral drugs which is cited for action against...
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Optimization of Analytical Procedure for In-hospital Rapid Quantification of Serum Level of Favipiravir in the Pharmacological Treatment of COVID-19
An in-hospital rapid method for quantifying the serum level of favipiravir (FPV) in the pharmacological treatment of COVID-19 was developed by an...
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Favipiravir – a Modern Antiviral Drug: Synthesis and Modifications
The routes of synthesis are considered, as well as the modifications of the promising modern antiviral drug favipiravir. Literature data from the...
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Favipiravir tautomerism: a theoretical insight
There is no experimental information about the tautomerism of Favipiravir ( T-705 ). Therefore, its tautomeric state was predicted by using density...
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Computational insight of repurpose drug for treatment of COVID-19: a CDFT approach
The COVID-19 is recognized as one of the deadly disease in the history of human life. It is caused by the severe acute respiratory syndrome...