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Nanomaterial Assisted Exosome Analysis Using Mass Spectrometry
Exosomes, extracellular vesicles (EVs) that play crucial roles in biological processes, have emerged as attractive targets for noninvasive disease...
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Comparative Analyses of Human Exosome Proteomes
Exosomes are responsible for cell-to-cell communication and serves as a valuable drug delivery vehicle. However, exosome heterogeneity,...
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Exosome for mRNA delivery: strategies and therapeutic applications
Messenger RNA (mRNA) has emerged as a promising therapeutic molecule with numerous clinical applications in treating central nervous system...
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Cell-Derived Exosome-Based Materials for Biomedical Applications
Exosomes are tiny membrane-bound vesicles of various compositions produced in the endosomal compartment of eukaryotic cells. These are secreted as... -
Exosome-mediated circGMPS facilitates the development of gastric cancer cells through miR-144-3p/PUM1
In recent years, gastric cancer (GC) is still one of the major public health burdens in the world. It is reported that exosome circular RNA (circRNA)...
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Activation of the Wnt/β-catenin signalling pathway enhances exosome production by hucMSCs and improves their capability to promote diabetic wound healing
BackgroundThe use of stem cell-derived exosomes (Exos) as therapeutic vehicles is receiving increasing attention. Exosome administration has several...
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Flexible electrochemical paper-based device for detection of breast cancer-derived exosome using nickel nanofoam 3D nanocomposite
Exosomes as new biomarkers for cancer diagnosis have attracted attention because they are highly released by tumor cells in various biological...
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An optimized exosome production strategy for enhanced yield while without sacrificing cargo loading efficiency
BackgroundExosome mediated mRNA delivery is a promising strategy for the treatment of multiple diseases. However, the low yield of exosomes is a...
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Exosome, the glass slipper for Cinderella of cancer—bladder cancer?
Exosomes are lipid bilayer vesicles with a diameter of 40–100 nm secreted by almost all cells. They have been found play crucial regulatory roles in...
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Cooked pork-derived exosome nanovesicles mediate metabolic disorder—microRNA could be the culprit
In this study, exosomes from cooked meat were extracted by ultra-high-speed centrifugation. Approximately 80% of exosome vesicles were within...
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A review on comparative studies addressing exosome isolation methods from body fluids
Exosomes emerged as valuable sources of disease biomarkers and new therapeutic tools. However, extracellular vesicles isolation with exosome-like...
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Current status and outlook of advances in exosome isolation
Exosomes are extracellular vesicles with a diameter ranging from 30 to 150 nm, which are an important medium for intercellular communication and are...
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Panax notoginseng: derived exosome-like nanoparticles attenuate ischemia reperfusion injury via altering microglia polarization
Cerebral ischemia/reperfusion (CI/R) injury is a clinical conundrum during the treatment of ischemic stroke. Cell-derived exosomes (CDE) were proved...
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An injectable, activated neutrophil-derived exosome mimetics/extracellular matrix hybrid hydrogel with antibacterial activity and wound healing promotion effect for diabetic wound therapy
Chronic diabetic wounds are primarily caused by infection, inflammation, and angiogenesis-related disorders. An ideal approach for treating chronic...
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Exosome-Transmitted miR-506-3p Inhibits Colorectal Cancer Cell Malignancy via Regulating GSTP1
Exosome-mediated microRNA transfer has been shown to regulate cancer progression. However, the involvement of exosomal-miR-506-3p in colorectal...
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Exosome inspired photo-triggered gelation hydrogel composite on modulating immune pathogenesis for treating rheumatoid arthritis
Although exosome therapy has been recognized as a promising strategy in the treatment of rheumatoid arthritis (RA), sustained modulation on RA...
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Exosome-based delivery strategies for tumor therapy: an update on modification, loading, and clinical application
Malignancy is a major public health problem and among the leading lethal diseases worldwide. Although the current tumor treatment methods have...
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Exosome-sheathed ROS-responsive nanogel to improve targeted therapy in perimenopausal depression
The development of natural membranes as coatings for nanoparticles to traverse the blood-brain barrier (BBB) presents an effective approach for...
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Exosome-derived circ_0001785 delays atherogenesis through the ceRNA network mechanism of miR-513a-5p/TGFBR3
PurposeEndothelial cell dysfunction is a major cause of early atherosclerosis. Although the role of extracellular vesicles in stabilizing...
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BMSC exosome-enriched acellular fish scale scaffolds promote bone regeneration
Tissue engineering scaffolds are essential for repairing bone defects. The use of biomimetic scaffolds for bone tissue engineering has been...