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Classification of Diverse Novel Diterpenoids
Diterpenoids serve as a vast source of terpenoidal compounds with a broad range of chemical and biological diversity and as well as providing a rich...
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Modular chemoenzymatic synthesis of ten fusicoccane diterpenoids
Fusicoccane diterpenoids display intriguing biological activities, including the ability to act as modulators of 14-3-3 protein–protein interactions....
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Dietary Diterpenoids
A number of foods, vegetables, fruits, and beverages (tea, coffee, and liqueur) contain many kinds of diterpenoids (mainly abietanes, cembranes,...
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Dietary Diterpenoids
A number of foods, vegetables, fruits, and beverages (tea, coffee, and liqueur) contain many kinds of diterpenoids (mainly abietanes, cembranes,...
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Two New Abietane Diterpenoids from Plectranthus barbatus
Plectranthus barbatus Andrews is one of the traditional herbs growing in the Okinawa region, Japan. This plant has high nutritional value and is well...
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Bioactive isopimarane and 3,4-seco isopimarane diterpenoids from Isodon amethystoides
Isodon amethystoides (Lamiaceae) is a popular plant in folk medicine in the southern provinces of China. Our phytochemical investigation of the twigs...
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Synthetic Transformations of Higher Terpenoids. 42*. Synthesis and Biological Activity of (Arylsulfonylureido)Diterpenoids with Various Substituents on the Aryl Fragment
The first (arylsulfonylureido)-substituted derivatives of tricyclic diterpenoids were synthesized by the reaction of isopimaric acid isocyanate with...
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Four Labdane Diterpenoids from Leonurus japonicus
A new labdane diterpenoid, leojaponotin ( 1 ), and three known labdane diterpenoids ( 2–4 ), were isolated from Leonurus japonicus . Their structures were...
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Theoretical Study on the Structures, Spectral Properties, and Drugability of Xenicane-type Diterpenoids from Dictyota dichotoma
T here are few reports on the relationship between the biological activity and structure of secondary metabolites from Dictyota dichotoma . In this...
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Biosynthesis of Biological Active Abietane Diterpenoids in Transformed Root Cultures of Salvia Species
Transformed root cultures of Salvia species are rich in abietane-type diterpenoids. These compounds have various biological activities, such as...
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Synthesis of Highly Functionalized Biologically Active Tetracyclic Diterpenoids from ent-Kaur-16-en-19-oic Acid under Modified Prévost-Woodward Reaction Conditions
AbstractA procedure has been developed for the synthesis of highly functionalized tetracyclic diterpenoids from natural ent -kaur-16-en-19-oic acid...
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Characterization of Crystals Isolated from the Caesalpinia sappan Seeds: A Comparative In Silico Analysis on Bioactivity of Sappan Diterpenoids
Objective. Caesalpinia sappan is a genus of plants belonging to the family Fabaceae found in East and Southeast Asia. Pharmacologically, species of...
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Secondary Metabolites from Chromolaena sinuata var. viscigerum
Two new labdane-type diterpenoids ( 1 , 2 ) have been isolated from the aerial parts of Chromolaena sinuata var. viscigerum (Asteraceae), along with six...
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Synthetic studies on tricyclic diterpenoids: convenient synthesis of 16-arylisopimaranes
AbstractA series of 16-arylisopimaranes has been synthesized by palladium-catalyzed arylation of the corresponding tricyclic diterpenoid isopimaric...
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Exploring optimal Taxol® CYP725A4 activity in Saccharomyces cerevisiae
BackgroundCYP725A4 catalyses the conversion of the first Taxol® precursor, taxadiene, to taxadiene-5α-ol (T5α-ol) and a range of other mono- and...
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Marine diterpenoid targets STING palmitoylation in mammalian cells
Natural products are important sources of therapeutic agents and useful drug discovery tools. The fused macrocycles and multiple stereocenters of...
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Marine Natural Products from Pseudopterogorgia elisabethae: Structures, Biosynthesis, Pharmacology, and Total Synthesis
In the late 1990s, the Caribbean octocoral Pseudopterogorgia elisabethae became the target of extensive chemical investigations leading to the...
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Salvimulticanol from Salvia multicaulis suppresses LPS-induced inflammation in RAW264.7 macrophages: in vitro and in silico studies
Sustained inflammatory responses can badly affect several vital organs and lead to chronic inflammation-related disorders, such as atherosclerosis,...
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Functional characterization and structural bases of two class I diterpene synthases in pimarane-type diterpene biosynthesis
Pimarane-type diterpenoids are widely distributed in all domains of life, but no structures or catalytic mechanisms of pimarane-type diterpene...
