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Comprehensive Analysis of circRNA, lncRNA, miRNA and mRNA Expression Profiles and Their Competing Endogenous RNA Networks in Hepatitis B Virus-Related Hepatocellular Carcinoma
Pursuing knowledge about circular RNA (circRNA), long non-coding RNA (lncRNA), microRNA (miRNA), and messenger RNA (mRNA) expression profiles and...
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The Study of mRNA Expression Profiles of Main Cell Function Regulator Genes in Unchanged Colon Mucosa from Healthy Donors
AbstractA comparative analysis of molecular genetic phenotypes of mucous membrane cells has been carried out in five anatomical regions of the large...
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Differential Expression of Nuclear-Encoded Mitochondrial Protein Genes of ATP Synthase Across Different Tissues of Female Buffalo
The physiological well-being of buffaloes, encompassing phenotypic traits, reproductive health, and productivity, depends on their energy status....
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Comprehensive Analysis of Differential Gene Expression Profile via RNA Sequencing in the Human Ovarian Cancer SKOV3 Cells Treated with Simvastatin
T he experimental studies have demonstrated that some statins have an anticancer effect against ovarian cancer in vitro and in vivo , however, the...
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Ozone reduces lifespan and alters gene expression profiles in Rhyzopertha dominica (Fabricius)
Rhyzopertha dominica is one of the most important stored grain pests that seriously damage rice and wheat. At present, the method of controlling...
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Differential expression of the genes encoding immune system components in response to Pseudomonas syringae and Pseudomonas aeruginosa in Arabidopsis thaliana
In innate immunity, the first layer of defense against any microbial infection is triggered by the perception of pathogen-associated molecular...
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Mechanism of differential expression of β-glucosidase genes in functional microbial communities in response to carbon catabolite repression
Backgroundβ-Glucosidase is the rate-limiting enzyme of cellulose degradation. It has been stipulated and established that β-glucosidase-producing...
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Tuning the Assembly of Bispecific Antibodies by Playing on Differential Polypeptide Chain Molar Ratios
Bispecific antibodies (bsAb) represent the most promising class of therapeutics due to their multiple mode of action. Their development raised...
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Insights into distinct signaling profiles of the µOR activated by diverse agonists
Drugs targeting the μ-opioid receptor (μOR) are the most effective analgesics available but are also associated with fatal respiratory depression...
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On the Time Presentation in Differential Rate Equations of Dynamic Microbial Inactivation and Growth
A dynamic (e.g., non-isothermal) kinetic model of microbial survival during a lethal process or growth under favorable conditions is either in the...
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Vitamin D status modulates innate immune responses and metabolomic profiles following acute prolonged cycling
PurposeThe influence of vitamin D status on exercise-induced immune dysfunction remains unclear. The aim of this study was to investigate the effects...
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Differential Gene Analysis of Langerhans Cell Histiocytosis and the Significance of MMP1-Targeted Drug Repositioning
Langerhans cell histiocytosis (LCH) is a rare condition predominantly affecting young children. Activation of the MAPK pathway has offered key new...
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PCR Analysis of the Expression of Chromosome 18 Genes in Human Liver Tissue: Interindividual Variability
AbstractUsing human chromosome 18 (Ch18) genes as an example, a PCR analysis of the interindividual variability of expression of 244 genes was...
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DNA-based molecular classifiers for the profiling of gene expression signatures
Although gene expression signatures offer tremendous potential in diseases diagnostic and prognostic, but massive gene expression signatures caused...
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Increased Immune Infiltration and Improved Prognosis of Head and Neck Squamous Cell Carcinoma Associated with Reduced Ancient Ubiquitous Protein 1 Gene Expression
This study aimed to explore the molecular mechanism underlying the prognostic role of ancient ubiquitous protein 1 (AUP1) in head and neck squamous...
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The Interplay Between Epilepsy and Parkinson’s Disease: Gene Expression Profiling and Functional Analysis
The results of many epidemiological studies suggest a bidirectional causality may exist between epilepsy and Parkinson’s disease (PD). However, the...
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Spatiotemporal Profiles of the Concentrations of Contaminants During Electrokinetic Remediation of Soils
AbstractAn empirical mathematical method is developed for studying spatiotemporal profiles (STPs) of pollutant concentrations in soils in the process...
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Investigating the impact of PACAP on thermal stability of G-actin by differential scanning calorimetry
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a bioactive peptide known for its diverse effects on the nervous system. While numerous...
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Exploring the response of PACAP on thermal endurance of F-actin by differential scanning calorimetry
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a bioactive peptide known for its diverse effects on the nervous system. While numerous...
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Differential expression of starch and sucrose metabolic genes linked to varying biomass yield in Miscanthus hybrids
BackgroundMiscanthus is a commercial lignocellulosic biomass crop owing to its high biomass productivity and low chemical input requirements. Within...
