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Inhibition of FLT1 Attenuates Neurodevelopmental Abnormalities and Cognitive Impairment in Offspring Caused by Maternal Prenatal Stress
Fms-like tyrosine kinase 1 (FLT1) has been shown to regulate processes such as angiogenesis, neurogenesis, and cognitive impairment. However, the...
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Effects of vitamins and polyunsaturated fatty acids on cognitive function in older adults with mild cognitive impairment: a meta-analysis of randomized controlled trials
PurposeVitamins and polyunsaturated fatty acids (PUFAs) have been studied extensively as safe and manageable nutrient interventions for mild...
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Prebiotics modulate the microbiota–gut–brain axis and ameliorate cognitive impairment in APP/PS1 mice
PurposePrebiotics, including fructo-oligosaccharides (FOS) and galacto-oligosaccharides (GOS), stimulate beneficial gut bacteria and may be helpful...
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Neuroprotective Effect of Ponicidin Alleviating the Diabetic Cognitive Impairment: Regulation of Gut Microbiota
Cognitive impairment is a major complication of diabetes mellitus, which is caused by constitutive hyperglycaemia. Ponicidin is a diterpenoid...
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Long-term Olfactory Functions in Patients with Subjective Cognitive Decline and Mild Cognitive Impairment
IntroductionOlfactory function is known to be impaired in patients with Alzheimer’s disease (AD) as well as in subjective cognitive decline (SCD) and...
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Plasma folate levels in relation to cognitive impairment: a community-based cohort of older adults in China
PurposeLower plasma level of folate has been associated with an increased risk of age-related cognitive impairment. However, studies that examined...
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Dietary factors in relation to the risk of cognitive impairment and physical frailty in Chinese older adults: a prospective cohort study
PurposeThe study aimed to investigate the independent associations of dietary factors with cognitive impairment (CI) and physical frailty (PF) among...
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Plasma extracellular vesicles reveal early molecular differences in amyloid positive patients with early-onset mild cognitive impairment
In the clinical course of Alzheimer’s disease (AD) development, the dementia phase is commonly preceded by a prodromal AD phase, which is mainly...
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Higher fruit and vegetable variety associated with lower risk of cognitive impairment in Chinese community-dwelling older men: a 4-year cohort study
PurposeFew studies have examined the variety in fruit and vegetable (FV) intake with cognitive impairment in older adults. This study examined the...
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Dietary and supplemental long-chain omega-3 fatty acids as moderators of cognitive impairment and Alzheimer’s disease
PurposeThere is an ever-growing body of literature examining the relationship between dietary omega-3 polyunsaturated fatty acids (ω3 PUFAs) and...
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Serum zinc concentration and dietary zinc intake in relation to cognitive function: an analysis of the REasons for Geographic and Racial Differences in Stroke (REGARDS) cohort
PurposeThere are several pathways by which zinc may be a modifiable factor to slow age-related cognitive decline. We investigated the associations...
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TrkB phosphorylation in serum extracellular vesicles correlates with cognitive function enhanced by ergothioneine in humans
Oral administration of the food-derived antioxidant amino acid ergothioneine (ERGO) results in its efficient distribution in the brain and enhances...
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The Western Diet Puzzle: Connecting Metabolic Dysfunction to Cognitive and Neurological Consequences
There has been a significant rise in the consumption of Western diet (WD), which are diets composed of high levels of processed sugar and saturated...
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Long-term effects of an egg-protein hydrolysate on cognitive performance and brain vascular function: a double-blind randomized controlled trial in adults with elevated subjective cognitive failures
PurposeShort-term intake of the egg-protein hydrolysate Newtricious (NWT)-03 improved executive function, but underlying mechanisms and long-term...
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Effect of MIND diet on cognitive function in elderly: a narrative review with emphasis on bioactive food ingredients
As the world becomes a super-aged society, cognitive decline is public health problems that are increasing rapidly. A healthy diet has great...
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Tangeretin confers neuroprotection, cognitive and memory enhancement in global cerebral ischemia in rats
Global cerebral ischemia is commonly associated with neurological deficits, including cognitive and memory impairments. The present study aims to...
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The association between adherence to a plant-based diet and cognitive ageing
PurposeWhile the benefits of adopting a more plant-based diet for sustainability and animal welfare are clear, its long-term health impacts,...
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Modern synthesis of cognitive enhancers: cholinergic ligands
The review outlines the methods for the synthesis of cognitive enhancers that are used as drugs that improve the cognitive abilities of healthy...
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Serum magnesium concentration and incident cognitive impairment: the reasons for geographic and racial differences in stroke study
PurposeTo examine the prospective association between serum Mg level and the incidence of cognitive impairment.
MethodsA random sub-cohort ( n = 2063...
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Tarooneh extract relieves anxiety-like behaviors and cognitive deficits by inhibiting synaptic loss in the hippocampus and frontal cortex in rats subjected to chronic restraint stress
In traditional medicine, Tarooneh (a hardcover of the date palm; Phoenix dactylifera) has known as a sedative and relaxant medicine. In this study,...
