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Chemical Biology: A Holistic Science
Chemical biology is the science that uses chemical substances, usually synthetically produced, to understand and manipulate complex biological...
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Carboranes in drug discovery, chemical biology and molecular imaging
There exists a paucity of structural innovation and limited molecular diversity associated with molecular frameworks in drug discovery and...
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Chemical Biology and Drug Discovery
The focus of this textbook is on application, rather than pure knowledge transfer of the results of all chemical biological work (which would also be...
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Tools for Understanding the Chemical Biology of the tRNA Epitranscriptome
Without changing the genetic code, dozens of chemical modifications comprising the epigenome and epitranscriptome participate in systems that...
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Tools for Understanding the Chemical Biology of the tRNA Epitranscriptome
Without changing the genetic code, dozens of chemical modifications comprising the epigenome and epitranscriptome participate in systems that...
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From Genomic Research to Chemical Biology
Another reason why the development of new drugs is difficult is grounded in genomic research. The genome codes for about 23,000 genes, that is, sites...
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Chemical Biology: Addressing New Drug Targets
Despite successes in genome research, the development of new drugs remains a challenge. The central problem is that the majority of genes and their...
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Engineering the Future through Synthetic Biology
The last two decades have witnessed tremendous progress in synthetic biology. Despite the technological advances, the maturing field has yet to...
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Chemical-Biology and Metabolomics Studies in Phage-Host Interactions
For many years, several studies have explored the molecular mechanisms involved in the infection of bacteria by their specific phages to understand...
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Harnessing nanotechnology to expand the toolbox of chemical biology
Although nanotechnology often addresses biomedical needs, nanoscale tools can also facilitate broad biological discovery. Nanoscale delivery,...
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RHAU Peptides Specific for Parallel G-Quadruplexes: Potential Applications in Chemical Biology
G-quadruplexes (G4s) are non-canonical nucleic acid structures formed by guanine (G)-rich sequences, which are ubiquitously found in the human genome...
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Gene expression modulation tools for bacterial synthetic biology
Synthetic biology has revolutionized the creation of microbial cell factories for the efficient production of value-added chemicals and materials...
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Chemical Modifications of Biomass
Biomass is a renewable resource that has several potential end uses, such as chemicals, biofuels, and cutting-edge materials. The carbon dioxide...
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Quantum Computing in the Next-Generation Computational Biology Landscape: From Protein Folding to Molecular Dynamics
Modern biological science is trying to solve the fundamental complex problems of molecular biology, which include protein folding, drug discovery,...
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Handbook of Chemical Biology of Nucleic Acids
This handbook is the first to comprehensively cover nucleic acids from fundamentals to recent advances and applications. It is divided into 10...
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Biofoundries: Bridging Automation and Biomanufacturing in Synthetic Biology
Biofoundries represent advanced automation facilities pivotal for streamlining the Design-Build-Test-Learn (DBTL) paradigm in biomanufacturing and...
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Chemical proteomics reveals the target landscape of 1,000 kinase inhibitors
Medicinal chemistry has discovered thousands of potent protein and lipid kinase inhibitors. These may be developed into therapeutic drugs or chemical...
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Chemical Equilibrium
Chemical equilibrium is the point in all chemical reactions at which there is no net change in the concentration of reactants or products. Chemical...