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Minimizing higher-order aggregation maximizes iron mobilization by small molecules
The natural product hinokitiol mobilizes iron across lipid bilayers at low concentrations and restores hemoglobinization in iron transporter...
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Antiplatelet effect of cudraxanthone B is related to inhibition of calcium mobilization, αIIbβ3 activation, and clot retraction
Cudrania tricuspidata ( C. tricuspidata ) is widespread throughout Asia and has known to have various physiological activities such as, inflammation,...
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Nanoplastics causes heart aging/myocardial cell senescence through the Ca2+/mtDNA/cGAS-STING signaling cascade
BackgroundNanoplastics (NPs) are now a new class of pollutants widely present in the soil, atmosphere, freshwater and marine environments....
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Effect of Different Extraction Methods on Anthocyanin Content in Hibiscus sabdariffa L. and their Antiplatelet and Vasorelaxant Properties
Hibiscus sabdariffa L. is a worldwide component for tea and beverages, being a natural source of anthocyanins, which are associated with...
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An up-scaled biotechnological approach for phosphorus-depleted rye bran as animal feed
Side streams from the milling industry offer excellent nutritional properties for animal feed; yet their use is constrained by the elevated...
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A microfluidic platform for simulating stem cell migration using in vivo-like gradients of stem cell mobilizer
Stem cell mobilization by cytokines and peptide drugs contributes to wound healing in injured tissues. Owing to the short half-life of cytokines and...
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Artocarpesin acts on human platelet aggregation through inhibition of cyclic nucleotides and MAPKs
The cardiovascular diseases (CVDs) are becoming a critical threat to our lives in these years. It is now widely accepted that platelets play an...
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Elemental composition of green tea infusions depending on the method of their brewing
Green tea infusions are a source of many bioactive compounds as well as elements, both nutrients and toxic ones. In this study, we assessed the...
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Effect of wildfire on soil element concentrations in Mediterranean Türkiye
The effect of the North Adrasan, Kumluca wildfire in 2016 on soil element concentrations has been evaluated. Samples were analyzed by neutron...
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Integration of poultry manure and phosphate solubilizing bacteria improved availability of Ca bound P in calcareous soils
A laboratory incubation experiment was executed to examine the role of phosphate solubilizing bacteria (with PSB and without PSB) and poultry manure...
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Appraisal of rock–water interaction and frailty of groundwater to corrosion and salinization, northwestern Gulf of Suez, Egypt
From 12 groundwater samples taken in Egypt's northwestern Suez Gulf, it can be concluded that the water is not suitable for drinking or irrigation...
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The effects of extracellular vesicles derived from Krüppel-Like Factor 2 overexpressing endothelial cells on the regulation of cardiac inflammation in the dilated cardiomyopathy
BackgroundDilated cardiomyopathy (DCM) is one of the common causes of heart failure. Myocardial injury triggers an inflammatory response and recruits...
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A novel method for transforming Geobacillus kaustophilus with a chromosomal segment of Bacillus subtilis transferred via pLS20-dependent conjugation
BackgroundGeobacillus kaustophilus is a thermophilic Gram-positive bacterium. Methods for its transformation are still under development. Earlier...
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Transgene Expression and Transposition Efficiency of Two-Component Slee** Beauty Transposon Vector Systems Utilizing Plasmid or mRNA Encoding the Transposase
The use of two-component transposon plasmid vector systems, namely, a transposase construct and a donor vector carrying the gene of interest (GOI)...
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210Po characteristic in selected thermal water sources in Northern Vietnam
There are eight famous thermal water sources, with medium temperature, neutral pH, high ranges of TDS values located in different carbonate...
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Capillary Isoelectric Focusing: Mass Spectrometry Method for the Separation and Online Characterization of Monoclonal Antibody Charge Variants at Intact and Subunit Levels
Monoclonal antibodies (mAbs) are one of the most widely used types of protein therapeutics. Charge variants are important quality attributes for...
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Synergistic Effects of Silicon and Phosphorus Co-Application on Rice (Oryza sativa L.) Growth, Yield and Nutrient Use Efficiency in Saline Soil
Despite the important role of silicon (Si) for the better utilization of plant nutrients, it is not well understood how the combinations of Si and P...
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QSAR Studies on Calcium Channel Blockers
Calcium channel blockers (CCBs) have potential therapeutic uses against several cardiovascular and non-cardiovascular diseases. For vasospastic...
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Alpha-lipoic acid modulates the diabetes mellitus-mediated neuropathic pain via inhibition of the TRPV1 channel, apoptosis, and oxidative stress in rats
Diabetes mellitus (DM) is a chronic syndrome involving neuropathic pain. Increased oxidative stress in DM is assumed to increase free reactive oxygen...
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Anti-thrombotic effects of arteanoflavone by regulating cyclic nucleotides and aggregation on human platelets
Excessive clotting or abnormal platelet accumulation can lead to serious cardiovascular disorders such as atherosclerosis, stroke, and thrombosis....
