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Recent developments of automated flow chemistry in pharmaceutical compounds synthesis
Recent developments in automated flow chemistry for pharmaceutical compound synthesis have garnered significant attention. Automation in synthesis...
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Rapid automated iterative small-molecule synthesis
Automated iterative small-molecule synthesis has the potential to advance and democratize the discovery of new medicines, materials and many other...
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Information Security in the Automated Production Control System at PAO Koks
Information security in the automated production control system at PAO Koks is discussed. Organizational and engineering aspects of security required...
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Automated stereocontrolled assembly-line synthesis of organic molecules
Automation has fuelled dramatic advances in fields such as proteomics and genomics by enabling non-experts to prepare, test and analyse complex...
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Automated synthesis of oxygen-producing catalysts from Martian meteorites by a robotic AI chemist
Living on Mars requires the ability to synthesize chemicals that are essential for survival, such as oxygen, from local Martian resources. However,...
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Development of an automated flow chemistry affinity-based purification process for DNA-encoded chemistry
An automated flow chemistry platform for DNA-encoded library (DEL) technologies requires the integration of a purification process for DNA-tagged...
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Reconfigurable liquid devices from liquid building blocks
Liquids are widely applied in the construction of various functional devices due to their abilities to flow, dissolve, deform and phase separate;...
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Automated solution-phase multiplicative synthesis of complex glycans up to a 1,080-mer
Carbohydrates play essential roles in nature, such as in cell–cell communication, cell growth and immunoresponse. However, the synthesis of...
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Synthesis and reactions of novel imidazo[4,5-b]pyridine building blocks
The synthesis of a novel imidazo[4,5- b ]pyridine and its partially saturated derivative relied on Michael addition of 1-methyl-1 H -imidazol-4-amine to...
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An Air-Impact Method for Mechanochemical Activation of Secondary Raw Materials in the Production of Building Materials
AbstractAn effective air-impact method for mechanochemical processes of activation of secondary raw materials in the production of building materials...
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Accelerated discovery of molecular nanojunction photocatalysts for hydrogen evolution by using automated screening and flow synthesis
Discovering and optimizing multicomponent organic semiconductors is typically a laborious process. High-throughput experimentation can accelerate...
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Current Researches in Modular Biofabrication: Tissue Building Blocks and Bioreactors
Modular tissue engineering (TE) is based on the design, fabrication, and arrangement of replicated microtissue constructs to generate functional...
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Development of an Automated Vertical Farm Module for Growing Plants Using Additive Technology
AbstractBased on the example of an automated module of a vertical farm for growing plants, an author’s method for develo** automated devices using...
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A perspective on automated advanced continuous flow manufacturing units for the upgrading of biobased chemicals toward pharmaceuticals
Biomass is a renewable, almost infinite reservoir of a large diversity of highly functionalized chemicals. The conversion of biomass toward biobased...
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Free and open-source QSAR-ready workflow for automated standardization of chemical structures in support of QSAR modeling
The rapid increase of publicly available chemical structures and associated experimental data presents a valuable opportunity to build robust QSAR...
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Automated Column Screening and Computer-Assisted Modeling for Analysis of Complex Drug Samples in Pharmaceutical Laboratories
New drug substances pose challenging process chemistry which requires adequate and fast advancement in analytical tools to avoid bottlenecks in drug...
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Robotic workflows for automated long-term adaptive laboratory evolution: improving ethanol utilization by Corynebacterium glutamicum
BackgroundAdaptive laboratory evolution (ALE) is known as a powerful tool for untargeted engineering of microbial strains and genomics research. It...
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Automated Construction and Optimization Combined with Machine Learning to Generate Pt(II) Methane C–H Activation Transition States
Quantum–mechanical transition states can aid in the identification of promising catalysts for methane C–H activation and functionalization. However,...
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Integration of experimental data and use of automated fitting methods in develo** protein force fields
The development of accurate protein force fields has been the cornerstone of molecular simulations for the past 50 years. During this period, many...
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Automated liquid handling robot for rapid lateral flow assay development
The lateral flow assay (LFA) is one of the most popular technologies on the point-of-care diagnostics market due to its low cost and ease of use,...
