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Cordycepin Ameliorates Psoriasis-Like Skin Lesion by Regulating p53/MDM2 Feedback Loop
Apoptosis is a natural physiological process of programmed cell death. It is essential for maintaining the homeostasis of the body and the immune...
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Phenylboronic acid-functionalized gelatin–oleic acid nanoparticles for high loading and efficient transdermal delivery of Celastrol towards the treatment of psoriasis
Systemic toxicity, poor aqueous solubility, and poorly cell permeable ability hindered the clinical application of Celastrol. In this study, we aimed...
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Anti-inflammatory effect of taxifolin in TNF-α/IL-17A/IFN-γ induced HaCaT human keratinocytes
Taxifolin, a bioactive flavonoid, has been attracting attention as a beneficial and valuable phytochemical due to its antioxidant, anticancer, and...
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Advances in the modulation of ROS and transdermal administration for anti-psoriatic nanotherapies
Reactive oxygen species (ROS) at supraphysiological concentration have a determinate role in contributing to immuno-metabolic disorders in the...
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Attenuation of Psoriasis Symptoms Following Treatment with C-phycocyanin from Spirulina Maxima in a Mouse Model
Psoriasis is a chronic autoimmune disease caused by an abnormal proliferation of keratinocytes in the epidermis. The efficacy of C-Phycocyanin, a...
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Anti-inflammation activity of brazilin in TNF-α induced human psoriasis dermatitis skin model
Psoriasis is a chronic inflammatory skin disease that causes erythema, scale, and invasion due to excessive proliferation of keratinocyte and...
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Deep eutectic solvent self-assembled reverse nanomicelles for transdermal delivery of sparingly soluble drugs
BackgroundTransdermal delivery of sparingly soluble drugs is challenging due to their low solubility and poor permeability. Deep eutectic solvent...
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Green Phellodendri Chinensis Cortex-based carbon dots for ameliorating imiquimod-induced psoriasis-like inflammation in mice
BackgroundCarbon dots (CDs) with multifaceted advantages have provided hope for development brand-new nanodrug for treating thorny diseases. This...
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Anti-Viral Potential of Curcumins: Ethnopharmacology, Chemistry, and Clinical Studies Focusing on Mechanism of Action and Future Perspectives
Viruses have always been a serious public health concern, and scientists have worked diligently to make new anti-viral medicines. Virus infections...
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Amentoflavone: Structure, Resources, Bioactivity and Pharmacology
Amentoflavone is a naturally occurring biflavonoid first identified in Selaginella species in 1971. Even before amentoflavone was isolated from...
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The Role of Andrographolide on Skin Inflammations and Modulation of Skin Barrier Functions in Human Keratinocyte
Andrographolide (AG) is a bioactive natural occurring compound found in a medicinal plant called Andrographis paniculata . AG is highly bioavailable...
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Antiviral Potential of Curcumins: Ethnopharmacology, Chemistry, and Clinical Studies Focusing on Mechanism of Action and Future Perspectives
Viruses have always been a serious public health concern, and scientists have worked diligently to make new antiviral medicines. Virus infections...
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310 nm UV-LEDs attenuate imiquimod-induced psoriasis-like skin lesions in C57BL/6 mice and inhibit IL-22-induced STAT3 expression in HaCaTcells
Ultraviolet light-emitting diodes (UV-LEDs) are a novel light source for phototherapy. This study aimed to evaluate the therapeutic effects of...
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Traditional Crude Drugs Against Encephalitis Infection: Ethnopharmacology, Chemistry, and Clinical and Preclinical Studies
Encephalitis infection is an infection in the brain causing inflammation of the brain. An infection or an autoimmune response generally causes...
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LncRNA MIR181A2HG negatively regulates human keratinocytes proliferation by binding SRSF1
Psoriasis is a common chronic inflammatory skin disease. Abnormal proliferation of keratinocytes plays an important role in the pathogenesis of...
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Babchi
Since ancient times, Psoralea corylifolia (Leguminosae), also known as babchi or babachi, has been used in various traditional systems of various...
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Coleus
Coleus is known as rapidly-growing plant with a trailing or spreading ability. It is widely present in various parts of world, such as, South Africa,...
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Mechanistic prospective and pharmacological attributes of quercetin in attenuation of different types of arthritis
Arthritis is a frequent autoimmune disease with undefined etiology and pathogenesis. Scientific community constantly fascinating quercetin (QUR), as...
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Deconvoluted plasma DSC curves on patients with psoriasis
Psoriasis is an inflammatory disease that changes plasma composition, and it is detectable by differential scanning calorimetry (DSC). Besides the...
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Preparation, Physicochemical Characterization, and Pharmacodynamic Study of Betamethasone Dipropionate Nanosuspension
AbstractNanosuspension of betamethasone dipropionate (BD), an insoluble glucocorticoid drug, was prepared using the medium grinding method, and the...
