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Design, Synthesis, and Characterization of Novel Substituted Dihydrooxazoles: Biological Evaluation and Molecular Docking
AbstractA novel series of 2-[(2-R-4-fluoro-3-(methylsulfanyl)phenyl]-4,5-dihydro-1,3-oxazoles were designed, synthesized, and evaluated for...
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Discovery of isoquinoline sulfonamides as allosteric gyrase inhibitors with activity against fluoroquinolone-resistant bacteria
Bacteria have evolved resistance to nearly all known antibacterials, emphasizing the need to identify antibiotics that operate via novel mechanisms....