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Computer-aided design of molecularly imprinted polymer reinforced by double hybrid monomers for selective purification of hydroxycamptothecin
AbstractA kind of hydroxycamptothecin (HCPT) hybrid molecularly imprinted polymer (AT/MA-HMIPs) with high selectivity and hard silicon skeleton was...
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Preparation of Folic Conjugated Magnetic Silica Mesoporous Nanoparticles and Their Encapsulated 10-HCPT Anticancer Behavior
A novel folate-decorated and magnetic mediated drug delivery system was fabricated by combining folate and magnetic nanoparticles to the surface of...
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A Self-assembled Nanoparticle Platform Based on Amphiphilic Oleanolic Acid Polyprodrug for Cancer Therapy
Oleanolic acid (OA) is a pentacyclic triterpenoid compound with extensive biological effects, such as anti-inflammatory and anticancer activities....
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Recent Advancements in the Field of Stimuli-Responsive Polymeric Nanomaterials for Cancer Treatment
Cancer has drawn a serious concern with rapid increase in the cases year by year. In order to control cancer, several treatment methods and surgery...
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Discovering and harnessing oxidative enzymes for chemoenzymatic synthesis and diversification of anticancer camptothecin analogues
Semi-synthetic derivatives of camptothecin, a quinoline alkaloid found in the Camptotheca acuminata tree, are potent anticancer agents. Here we...
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Injectable biocompatible nanocomposites of Prussian blue nanoparticles and bacterial cellulose as a safe and effective photothermal cancer therapy
Photothermal therapy (PTT) is a novel cancer treatment using a photoabsorber to cause hyperthermia to kill tumors by laser irradiation. Prussian blue...
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Customizing cancer treatment at the nanoscale: a focus on anaplastic thyroid cancer therapy
Anaplastic thyroid cancer (ATC) is a rare but highly aggressive kind of thyroid cancer. Various therapeutic methods have been considered for the...
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Nanoparticles for Targeted Drug Delivery Systems with Cancer Therapy in Perspective
Cancer is a lethal disease and is one of the leading causes of morbidity worldwide. Chemotherapy is successful to combat cancer but medical...
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Emerging Carbon-Based Nanomaterials for Biomedical and Bioengineering Applications
Nanomaterials are emerging candidates for biomedical and bioengineering applications. Among them, carbon-based nanomaterials have the potential to...
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Recent advancements of electrospun nanofibers for cancer therapy
Nanotechnology is a rapidly increasing scientific field due to its immense potential for develo** new materials with exceptional...
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Smart Nanomaterials for Alleviating the Limitation of Photodynamic Therapy
Photodynamic therapy (PDT) is one of the widely accepted treatment modalities for cancers, infectious diseases, and other diseases. PDT attained much...
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Emerging nanobiotechnology for precise theranostics of hepatocellular carcinoma
Primary liver cancer has become the second most fatal cancer in the world, and its five-year survival rate is only 10%. Most patients are in the...
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Mesoporous nanodrug delivery system: a powerful tool for a new paradigm of remodeling of the tumor microenvironment
Tumor microenvironment (TME) plays an important role in tumor progression, metastasis and therapy resistance. Remodeling the TME has recently been...
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CTAB-assisted fabrication of well-shaped PDA-based colloidosomes
Colloidosomes have gained intensive attention in the past years due to their substantial applications in wide scopes involving encapsulation,...
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CPP Functionalized Nanoparticles
In this chapter, the delivery of biomoleculesLiposome such as oligonucleotidesOligonucleotide, proteins, peptides and others by connection of the...
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Nanoencapsulation and delivery of bioactive ingredients using zein nanocarriers: approaches, characterization, applications, and perspectives
Zein has garnered widespread attention as a versatile material for nanosized delivery systems due to its unique self-assembly properties,...
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Milk protein-based nanodelivery systems for the cancer treatment
The numerous advantages that nanotechnology can bring to the design of pharmaceutical delivery systems are perhaps nowhere better illustrated than in...
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Bioorthogonal Chemistry in Cellular Organelles
While bioorthogonal reactions are routinely employed in living cells and organisms, their application within individual organelles remains limited....
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Synthesis of Camptothecin-10-O-glucoside Using an Engineered Oleandomycin Glucosyltransferase
Oleandomycin glycosyltransferase variant P67T/S132F/A242V(ASP) was used to convert 10-hydroxy-camptothecin into camptothecin-10- O -glucoside, which...
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Anticancer and Apoptotic-Inducing Effects of Rutin-Chitosan Nanoconjugates in Triple Negative Breast Cancer Cells
Cancer includes a range of diseases that arise as a result of the unregulated growth of malignant cells, which have the potential to invade or spread...
