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Comparing various protocols of human and bovine ovarian tissue decellularization to prepare extracellular matrix-alginate scaffold for better follicle development in vitro
BackgroundNowadays, the number of cancer survivors is significantly increasing as a result of efficient chemo/radio therapeutic treatments. Female...
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Electrically Conductive Nanofibers Composed of Chitosan-grafted Polythiophene and Poly(ε-caprolactone) as Tissue Engineering Scaffold
Two novel electrically conductive nanofibrous scaffolds based on chitosan- grafted polythiophene (CS- g -PTh), and chitosan- grafted ...
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Alginate Nonwoven-Sponge Composite Scaffold for Rotator Cuff Tendon Repair
Growth factor-mediated healing of rotator cuff tendon requires to develop a clinically applicable biomaterial playing roles of mechanical support and...
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Four Three-winged Nitrogenous Heterocyclic Derivatives of Citric Acid Scaffold: The First Synthesis and Characterization of These Newly Discovered Fan-like Compounds
AbstractCitric acid is a very important scaffold and intermediate in organic/medicinal chemistry and biochemistry, as it is the most famous...
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Probing the competitive inhibitor efficacy of frog-skin alpha helical AMPs identified against ACE2 binding to SARS-CoV-2 S1 spike protein as therapeutic scaffold to prevent COVID-19
In COVID-19 infection, the SARS-CoV-2 spike protein S1 interacts to the ACE2 receptor of human host, instigating the viral infection. To examine the...
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Relative free-energy calculations for scaffold hop**-type transformations with an automated RE-EDS sampling procedure
The calculation of relative free-energy differences between different compounds plays an important role in drug design to identify potent binders for...
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Flake-like glass nanoparticles reinforced natural polymeric scaffold as a promising substrate for bone regeneration
Natural polymeric scaffolds with unique characteristics can be considered as the best candidates for tissue engineering applications. But improve the...
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Tracheal In Vitro Reconstruction Using a Decellularized Bio-Scaffold in Combination with a Rotating Bioreactor
Long-segment airway stenosis as well as their neoplastic transformation is life-threatening and still currently represent unsolved clinical problems.... -
In silico evolution of nucleic acid-binding proteins from a nonfunctional scaffold
Directed evolution emulates the process of natural selection to produce proteins with improved or altered functions. These approaches have proven to...
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Wound Dressing Scaffold with High Anti-biofilm Performance Based on Ciprofloxacin-Loaded Chitosan-Hydrolyzed Starch Nanocomposite: In Vitro and In Vivo Study
Today, the search for solutions to reduce wound infection and restore wound receptivity also reduces its side effects which are a difficult problem...
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Optimizing material and manufacturing process for PEGDA/CNF aerogel scaffold
Cellulose nano fibril (CNF) aerogel, which is provided with high porosity, ultralow density and biodegradable ability, is a promising material for...
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Vision on Synthetic and Medicinal Facets of 1,2,4-Triazolo[3,4-b][1,3,4]thiadiazine Scaffold
The present review article strives to compile the latest synthetic approaches for the synthesis of triazolothiadiazine and its derivatives, along...
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Potential use of 3D-printed graphene oxide scaffold for construction of the cartilage layer
BackgroundThree-dimensional (3D) printing involves the layering of seed cells, biologically compatible scaffolds, and biological activity factors to...
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The Effect of Bulk Electrospun Polycaprolactone-graphene Oxide Scaffold on the Healing of Defected Femur Cartilage on a Rabbit Model
In this study, bulk and non-bulk electrospun scaffolds from polycaprolactone (PCL) containing graphene oxide (GO) were fabricated. Graphene oxide...
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GO containing PHBHX bone scaffold: GO concentration and in vitro osteointegration
Trauma, congenital abnormalities or cancer-induced bone defects can be treated with tissue engineering products. Graphene oxide-containing polymeric...
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Synthesis of novel carbazole hydrazine-carbothioamide scaffold as potent antioxidant, anticancer and antimicrobial agents
BackgroundCarbazole-based molecules containing thiosemicarbazide functional groups are recognized for their diverse biological activities,...
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Development of an Electrospun Scaffold for Retinal Tissue Engineering
AbstractDelivery of retinal progenitor cells (RPCs) for restoring injured or diseased retinal tissue using biodegradable scaffolds is a promising...
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The First Representatives of Phosphonium Salts Based on the Ammonium Acylhydrazone Scaffold: Synthesis and Biological Activity
AbstractThe acid-catalyzed reaction of substituted benzaldehydes with Girard’s reagent T leads to the formation of new water-soluble mixed...
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Development of an implantable PCL/alginate bilayer scaffold to prevent secondary infections
Drug-releasing implantable scaffolds have been used for a variety of biomedical applications. Sustained release of drugs, including antibacterial...
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Preparation and Characterization of PLA Film/3D Printing Composite Scaffold for Tissue Engineering Application
Three-dimensional (3D) printing technology provides an effective alternative for tissue engineering scaffold. In this paper, a composite scaffold...