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n-3 PUFA and caloric restriction diet alters lipidomic profiles in obese men with metabolic syndrome: a preliminary open study
PurposeFor people with metabolic syndrome (MetS), altering the macronutrient composition of their diets might ameliorate metabolic abnormalities. The...
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Spatially Resolved Quantitation of Drug in Skin Equivalents Using Mass Spectrometry Imaging (MSI)
Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging (MSI) has seen a growing interest as a leading technique in the...
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Efficient lipidomic approach for the discovery of lipid ligands for immune receptors by combining LC-HRMS/MS analysis with fractionation and reporter cell assay
C-type lectin receptors (CLRs), which are pattern recognition receptors responsible for triggering innate immune responses, recognize damaged...
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Ion Mobility-Mass Spectrometry in Food and Environmental Chemistry
Ion mobility-mass spectrometry (IM-MS) has emerged as a powerful analytical technique currently used in numerous fields including food and...
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Significance of Various Aspects of Food Microbiology, Fermentation, and Latest Technology and Its Impact on Human Health
Microbiology is important for food safety, production, processing, storage, and preservation. People have used yeast, mold, and bacteria for...
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Evaluation of LC-MS and LC×LC-MS in analysis of zebrafish embryo samples for comprehensive lipid profiling
In this study, both conventional one-dimensional liquid chromatography (1DLC) and comprehensive two-dimensional liquid chromatography (2DLC) coupled...
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Lipid Oxidation in Meat Systems: Updated Means of Detection and Innovative Antioxidant Strategies
Lipid oxidation is recognized as a main threat to meat quality, owing to its impact on the nutritional value and sensory properties of processed...
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A high-throughput platform for detailed lipidomic analysis of a range of mouse and human tissues
Lipidomics is of increasing interest in studies of biological systems. However, high-throughput data collection and processing remains non-trivial,...
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Sequential lipidomic, metabolomic, and proteomic analyses of serum, liver, and heart tissue specimens from peroxisomal biogenesis factor 11α knockout mice
Peroxisomes are versatile single membrane-enclosed cytoplasmic organelles, involved in reactive oxygen species (ROS) and lipid metabolism and diverse...
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IDSL_MINT: a deep learning framework to predict molecular fingerprints from mass spectra
AbstractThe majority of tandem mass spectrometry (MS/MS) spectra in untargeted metabolomics and exposomics studies lack any annotation. Our deep...
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Optimized Identification of Triacylglycerols in Milk by HPLC-HRMS
This work has developed an optimized workflow for the targeted analysis of triacylglycerols (TAGs) in milk by liquid chromatography coupled with a...
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Lipid metabolism of leukocytes in the unstimulated and activated states
Lipidomics has emerged as a powerful technique to study cellular lipid metabolism. As the lipidome contains numerous isomeric and isobaric species...
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Evaluation of lipid quantification accuracy using HILIC and RPLC MS on the example of NIST® SRM® 1950 metabolites in human plasma
Lipidomics analysis for large-scale studies aiming at the identification and quantification of natural lipidomes is often performed using LC–MS-based...
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Prospects for Using Chromatography–Mass Spectrometry for the Determination of Lipids in Clinical Cardiolipidology
AbstractCardiolipidology – a new direction in cardiology – is develo** intensively owing to the method of mass spectrometry. This method has...
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(CO2)n+, (H2O)n+, and (H2O)n+ (CO2) gas cluster ion beam secondary ion mass spectrometry: analysis of lipid extracts, cells, and Alzheimer’s model mouse brain tissue
This work assesses the potential of new water cluster-based ion beams for improving the capabilities of secondary ion mass spectrometry (SIMS) for in...
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Applications of 2DLC
It has been shown that two-dimensional liquid chromatography offers a way to greatly increase the number of compounds that can be separated, detected...
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Mass Fingerprinting for High-Throughput Analyses of Food: Authentication and Quality Control
Mass fingerprinting is a fast and straightforward approach for analyzing the chemical composition of biological materials. This chapter details how...