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Biocomposites and Bioceramics in Tissue Engineering: Beyond the Next Decade
Current strategies in the field of tissue engineeringTissue Engineering are bringing functional biomaterialsBiomaterials with required structural,...
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The mTOR/ULK1 signaling pathway mediates the autophagy-promoting and osteogenic effects of dicalcium silicate nanoparticles
A novel bioactive inorganic material containing silicon, calcium and oxygen, calcium silicate (Ca 2 SiO 4 , C 2 S) with a CaO-SiO 2 ingredient, has been...
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Cell-Derived Matrix, Stem Cell Rejuvenation, and Tissue Regeneration
Extracellular matrix (ECM), the major component of tissue, plays a critical role in tissue engineering and regeneration. It is well-known that...
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Recent developments of biomaterial scaffolds and regenerative approaches for craniomaxillofacial bone tissue engineering
Bone defects in the craniomaxillofacial (CMF) region occur as a result of trauma, cancer excisions, congenital defects and deformities. CMF bone...
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An in vitro Study on the Biocompatibility of Titanium Implants Made by Selective Laser Melting
Customized medical implants obtained by selective laser melting have an important applicability due the accurate architecture which promotes the...
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Cell unit-inspired natural nano-based biomaterials as versatile building blocks for bone/cartilage regeneration
The regeneration of weight-bearing bone defects and critical-sized cartilage defects remains a significant challenge. A wide range of...
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Fabrication and Characterization of 3D Nanostructured Polycaprolactone-Gelatin/Nanohydroxyapatite-Nanoclay Scaffolds for Bone Tissue Regeneration
Numerous clinical bone disorders, such as infections and bone loss from cancer or trauma, increase the need for bone regeneration. Due to the...
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Osteoplastic Material Based on a Bone Matrix Resistant to Osteoclastic Resorption under Conditions of a Pronounced Regenerative Process as a Carrier for rhBMP
AbstractA technology has been developed for obtaining and evaluating in model studies in vitro a chemically fixed xenogenic bone matrix structurally...
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Nano-fluorcanasite-fluorapatite Reinforced Poly-ε-caprolactone Based Biomimetic Scaffold: A Synergistic Approach Towards Generation of Conducive Environment for Cell Survival
This paper reports the development of bioactive fluorcanasite-fluorapatite nanoparticle (nFC-FAp) reinforced poly-(ε-caprolactone) (PCL)...
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Photodynamic and nitric oxide therapy-based synergistic antimicrobial nanoplatform: an advanced root canal irrigation system for endodontic bacterial infections
BackgroundThe main issues faced during the treatment of apical periodontitis are the management of bacterial infection and the facilitation of the...
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Biomedical applications of silica-based aerogels: a comprehensive review
Silica-based aerogels are the appropriate and well-known porous materials that have become interesting in science and technology, especially in the...
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Current progress and limitations of research regarding the therapeutic use of adipose-derived stem cells: literature review
BackgroundAdipose tissue has recently become one of the most promising and predominant sources of mesenchymal stem cells owing to its high...
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Development and characterization of PCL membranes incorporated with Zn-doped bioactive glass produced by electrospinning for osteogenesis evaluation
The integration of biomaterials in tissue regeneration has been showing effectiveness in the treatment of diseases related to bone structure and...
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Magnesium malate-modified calcium phosphate bone cement promotes the repair of vertebral bone defects in minipigs via regulating CGRP
Active artificial bone substitutes are crucial in bone repair and reconstruction. Calcium phosphate bone cement (CPC) is known for its...
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Current Researches in Modular Biofabrication: Tissue Building Blocks and Bioreactors
Modular tissue engineering (TE) is based on the design, fabrication, and arrangement of replicated microtissue constructs to generate functional...
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Hexagonal Boron Nitride/PCL/PLG Coatings on Borate Bioactive Glass Scaffolds for Bone Regeneration
In this study, hexagonal boron nitride (hBN) nanoparticle- containing (0.1–2 wt%) polycaprolactone (PCL) and polylactic-co-glycolic acid (PLG)-coated...
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Bioactive Antibacterial Modification of Orthodontic Microimplants Using Chitosan Biopolymer
Titanium alloy (Ti6Al4V)-based microimplants are extensively used as anchorage units in orthodontic treatment; however, they have a high failure rate...
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Designing Elastic Modulus of Cell Culture Substrate to Regulate YAP and RUNX2 Localization for Controlling Differentiation of Human Mesenchymal Stem Cells
To establish a guideline for the design of cell culture substrates to control human mesenchymal stem cell (MSC) differentiation, we quantitatively...
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Fabrication of poly(lactic acid)-cellulose acetate core-shell electrospun fibers with improved tensile strength and biocompatibility for bone tissue engineering
The employment of individual poly(lactic acid) (PLA) or cellulose acetate (CA) electrospun fibers as bone tissue replacement was restricted by the...
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Recent insights into the microRNA and long non-coding RNA-mediated regulation of stem cell populations
Stem cells are undifferentiated cells that have multi-lineage differentiation. The transition from self-renewal to differentiation requires rapid and...
