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1. High production of triterpenoids in Yarrowia lipolytica through manipulation of lipid components

   Background

   Lupeol exhibits novel physiological and pharmacological activities, such as anticancer and immunity-enhancing activities. However,...

   **-Lai Zhang, Qiu-Yan Bai, ... Ying-** Yuan in Biotechnology for Biofuels

   Article Open access 29 July 2020
   

2. Synthesis of fluorescent nanoprobe with simultaneous response to intracellular pH and Zn²⁺ for tumor cell distinguishment

   A novel dual-functional nanoprobe was designed and synthesized by facile assembly of quinoline derivative (PEIQ) and meso-tetra (4-carboxyphenyl)...

   Qin Wang, Yupeng Shi, ... Changqing Yi in Microchimica Acta

   Article 02 January 2021
   

3. Generation and Characterization of In Vitro Transcribed mRNA

   Here we describe the in vitro preparation of mRNA from DNA templates, including setting up the transcription reaction, mRNA cap**, and mRNA...

   Cristina Poveda, Yi-Lin Chen, Ulrich Strych in RNA Vaccines

   Protocol 2024
   

4. Gene Delivery Using Polymer Therapeutics

   The use of polymers as synthetic non-viral carriers for introducing nucleic acids into cells appears very appealing. Polymers can be generated in...

   Ernst Wagner, Julia Kloeckner in Polymer Therapeutics I

   Chapter
   

5. Screening and evaluation of anti-SARS-CoV-2 components from Ephedra sinica by ACE2/CMC-HPLC-IT-TOF-MS approach

   Traditional Chinese medicines played an important role in the treatment of COVID-19 in 2020. Ephedra sinica , one of the major constituent herbs of...

   Yanni Lv, Saisai Wang, ... Langchong He in Analytical and Bioanalytical Chemistry

   Article 19 February 2021
   

6. Protective Effect of the Intracellular Content from Potential Probiotic Bacteria against Oxidative Damage Induced by Acrylamide in Human Erythrocytes

   The aim of this study was to assess the protective effect of the intracellular content obtained from potential probiotic bacteria against...

   P.F. Cuevas-González, J.E. Aguilar-Toalá, ... A. Hernández-Mendoza in Probiotics and Antimicrobial Proteins

   Article 22 January 2020
   

7. Dual-emissive carbon dots for dual-channel ratiometric fluorometric determination of pH and mercury ion and intracellular imaging

   Dual-emissive carbon dots (CDs) were fabricated for dual-channel ratiometric fluorometric determination of pH and mercury ion (Hg ²⁺ ) and...

   Ruiqing Long, Cui Tang, ... Shuyun Shi in Microchimica Acta

   Article 01 May 2020
   

8. Adipose triglyceride lipase suppresses noncanonical inflammasome by hydrolyzing LPS

   Intracellular recognition of lipopolysaccharide (LPS) by mouse caspase-11 or human caspase-4 is a vital event for the activation of the noncanonical...

   Weitao Li, Qiannv Liu, ... Pengyan **a in Nature Chemical Biology

   Article 27 February 2024
   

9. Preparation of Chromobodies for the Detection of Cell Surface Epitopes

   Chromobodies are nanobodies genetically fused to fluorescent proteins, which were developed to visualize endogenous intracellular antigens. These...

   Ugne Baronaite, Elise Cachat in Mammalian Synthetic Systems

   Protocol 2024
   

10. In Vitro Detected hly II Cytotoxin in a Strain of Staphylococcus aureus (BM S-2) and Plant-Derived Aromatic Components: a Molecular Docking Study

    In time, diagnosis and detection of virulence factor and its pathogenomics study continues to grow and this leads to novel treatments for infectious...

    Debadarshee Das Mohapatra, Smaranika Pattnaik, Sruti Panda in Applied Biochemistry and Biotechnology

    Article 09 February 2021
    

11. Molecular Conjugates

    Molecular conjugates are nanometer-sized entities consisting of synthetic materials (lipids, polycations, targeting agents, and so on) and nucleic...

    Jeremy Heidel, Swaroop Mishra, Mark E. Davis in Gene Therapy and Gene Delivery Systems

    Chapter
    

12. Photoregulation of the biosynthetic activity of the edible medicinal mushroom Lentinula edodes in vitro

    Abstract

    The findings of the study demonstrate the impact of low-intensity laser and quasi-monochromatic light on the biosynthetic activity of the...

    Oksana Mykchaylova, Halyna Dubova, ... Natalia Poyedinok in Photochemical & Photobiological Sciences

    Article 30 January 2024
    

13. Near-infrared-activated anticancer platinum(IV) complexes directly photooxidize biomolecules in an oxygen-independent manner

    Conventional light-driven cancer therapeutics require oxygen and visible light to indirectly damage biomolecules, limiting their efficacy in deep,...

    Zhiqin Deng, Huangcan Li, ... Guangyu Zhu in Nature Chemistry

    Article 22 June 2023
    

14. Fluorescence Correlation Spectroscopy with Autofluorescent Proteins

    Fluorescence correlation spectroscopy (FCS) is a versatile technique operating at the single-molecule level, that successfully meets many challenges...

    Tobias Kohl, Petra Schwille in Microscopy Techniques

    Chapter
    

15. Quantitative control of subcellular protein localization with a photochromic dimerizer

    Artificial control of intracellular protein dynamics with high precision provides deep insight into complicated biomolecular networks. Optogenetics...

    Takato Mashita, Toshiyuki Kowada, ... Shin Mizukami in Nature Chemical Biology

    Article 18 June 2024
    

16. Effect of environmental water activity on microbial inactivation by intense pulsed light (IPL)

    In this study, the effect of environmental a _w on microbial inactivation by intense pulsed light (IPL) was investigated. Three different...

    Hee-Jeong Hwang, Jee-Woo Kim, ... Myong-Soo Chung in Food Science and Biotechnology

    Article 26 July 2023
    

17. Cysteine facilitates the lignocellulolytic response of Trichoderma guizhouense NJAU4742 by indirectly up-regulating membrane sugar transporters

    Background

    Filamentous fungi possess a rich CAZymes system, which is widely studied and applied in the bio-conversion of plant biomass to alcohol...

    Yang Liu, Tuo Li, ... Dongyang Liu in Biotechnology for Biofuels and Bioproducts

    Article Open access 27 October 2023
    

18. Methionine inducing carbohydrate esterase secretion of Trichoderma harzianum enhances the accessibility of substrate glycosidic bonds

    Background

    The conversion of plant biomass into biochemicals is a promising way to alleviate energy shortage, which depends on efficient microbial...

    Yang Liu, Tuo Li, ... Qirong Shen in Microbial Cell Factories

    Article Open access 26 April 2024
    

19. Protective effects of Aureobasidium pullulans lysate on UV-damaged human skin fibroblasts and HaCaT cells

    Background

    Aureobasidium pullulans ( A. pullulans ) has a wide range of applications. Ultraviolet (UV) rays from the sun can cause skin photoaging. In...

    **n Wang, Yongtao Zhang, ... Changtao Wang in Bioresources and Bioprocessing

    Article Open access 28 August 2023
    

20. Stimuli-responsive nanoformulations for CRISPR-Cas9 genome editing

    The CRISPR-Cas9 technology has changed the landscape of genome editing and has demonstrated extraordinary potential for treating otherwise incurable...

    Tianxu Fang, **aona Cao, ... Guojun Chen in Journal of Nanobiotechnology

    Article Open access 02 August 2022