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Thin-layer chromatography quantification of ibuprofen using digital imaging
Ibuprofen is a pharmaceutical that is commonly used to reduce inflammation and to treat headaches. A thin-layer chromatographic method combined with...
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High-performance thin-layer chromatography-based method development for the analysis of 4-methoxy-2-nitroaniline as potential genotoxic impurity
Omeprazole contains benzimidazole substitute, and it acts as a proton-pump inhibitor used for gastroduodenal ulcers. 4-Methoxy-2-nitroaniline is a...
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Combination of high-performance thin-layer chromatography and liquid chromatography–quadrupole time-of-flight–tandem mass spectrometry analysis: a promising analytical tool for discrimination between oleo-gum resin of raw and purified Commiphora wightii
Guggulu ( Commiphora wightii oleo-gum resin) is exported in more than 42 countries including developed countries like the United Kingdom and the...
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Concurrent quantification of oleanolic acid, β-sitosterol and lupeol by a validated high-performance thin-layer chromatography method in Urginea indica Kunth bulb
A validated high-performance thin-layer chromatography (HPTLC) method was developed for the simultaneous quantification of oleanolic acid,...
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Simultaneous estimation of (α + β) boswellic acids, β-asarone, isoeugenol, 6-gingerol, and piperine in Majun Nisyan by high-performance thin-layer chromatography
Majun Nisyan (MJN) is a polyherbal formulation used in Unani medicine for its therapeutic efficacy against Nisyan (forgetfulness/dementia). In the...
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Reversed-phase thin-layer chromatography and ultra-performance liquid chromatography/mass spectrometry to estimate the drug likeness of phosphodiesterase 10A inhibitors with phthalimide core
Lipophilicity is a physicochemical parameter well known as a decisive factor for predicting the successful development of a drug. Thus, a balance...
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Development and validation of a high-performance thin-layer chromatography‒densitometric method and mass spectroscopy profiling for the determination of bioactive phytosterol from Manilkara zapota L. P. Royen leaves and correlating its antioxidant and antiinflammatory potential
A simple, reliable high-performance thin-layer chromatography (HPTLC)‒densitometry method was developed and validated for the quantification of...
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Application of thin-layer chromatography in the assessment of bioactivity properties of isatin derivatives
In the last 20 years, isatin and its derivatives stand out as promising precursors in the synthesis of new pharmacologically active compounds. Since...
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A validated high‑performance thin-layer chromatography method for the simultaneous determination of quercetin and gallic acid in Annona reticulata L.
A sensitive and reliable high-performance thin-layer chromatography (HPTLC) method has been developed to simultaneously estimate quercetin and gallic...
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High-performance thin-layer chromatography in combination with an acetylcholinesterase-inhibition bioassay with pre-oxidation of organothiophosphates to determine neurotoxic effects in storm, waste, and surface water
Pesticides such as organothiophosphates (OTPs) are neurotoxically active and enter the aquatic environment. Bioassays, using acetylcholinesterase...
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Estimation of betulinic acid from wild fruit extracts of Ziziphus mauritiana and Ziziphus nummularia from different regions of North India by a validated high-performance thin-layer chromatography method
The Ziziphus fruits are recognized as a rich source of biologically active compounds, such as polysaccharides, phenolics, triterpenes, saponins, etc....
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Micellar Thin-Layer Chromatography and Preconcentration of L-Carnitine with Magnetite Nanoparticles
AbstractThin-layer chromatography (TLC) is used to study the chromatographic behavior of L-carnitine in aqueous–organic mobile phases (MPs) and...
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High-performance flash chromatography on fine-grained silica gel
A novel method of high-performance flash chromatography was proposed. The method allows one to separate mixtures of substances ranging from hundreds...
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Exploration and practice on systematic identification strategy of traditional Chinese medicine prescriptions by high-performance thin-layer chromatography—with Daqinjiao decoction as an example
Chinese medicine formula has been the main dosage form of Traditional Chinese Medicine (TCM) in clinics, which has been widely applied in China,...
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High-performance thin-layer chromatography method development and validation for quantification of glucuronic acid in gum samples of Sterculia urens Roxb.
A simple, accurate and precise high-performance thin-layer chromatography (HPTLC) method has been developed and validated for the quantification of...
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A validated quantification of gallic acid and ellagic acid in Triphala using a high-performance thin-layer chromatography method
A well-known Ayurvedic preparation, Triphala, consists of Amla ( Emblica officinalis Gaertn.), Baheda ( Terminalia bellirica Roxb.) and Harad ( Terminali...
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Quality control in pharmaceutical analysis by diode-array thin-layer chromatography: quantification of trimethoprim and sulfamethoxazole as a case study
The combination of trimethoprim and sulfamethoxazole as a fixed-dose combination in the ratio 1:5 is known as cotrimoxazole. It is used as antibiotic...
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Marker-based standardization of Terminalia arjuna bark for the detection of probable adulterants by quantitative high-performance thin-layer chromatography
The bark of Terminalia arjuna (Combretaceae) is traditionally used for cardio-protective and cardio-strengthening properties worldwide. It is rich in...
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High-performance thin-layer chromatography (HPTLC) method development and validation for the estimation of curcumin and cineole
Curcumin and cineole are phytochemicals which have shown synergistic effects in allergic rhinitis (AR). The aim of the current work was to develop a...
