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New fluorescent analogs of bacterial undecaprenyldiphosphate galactose
A synthesis of four new analogs of bacterial undecaprenyldiphosphate galactose, in which the oligoisoprenoid moiety is replaced with a linear...
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Major Advances in the Development of Synthetic Oligosaccharide -Based Vaccines
Because of their involvement in a variety of different biological processes and their occurrence onto pathogens and malignant cell surface,...
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Stereoelectronic Effects in Nucleosides and Nucleotides
An excellent review of this subject was published in 2005 by Chattopadhyaya et al. [1].
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Quantitative HPLC-MS analysis of nucleotide sugars in plant cells following off-line SPE sample preparation
An analytical workflow was developed for the absolute quantification of uridine diphosphate (UDP)-sugars in plant material in order to compare their...
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The complex structures of ALKBH2 mutants cross-linked to dsDNA reveal the conformational swing of β-hairpin
Mammalian AlkB homologue 2 (ALKBH2) is the primary housekee** DNA demethylase, effectively repairing endogenously formed methylated lesions in...
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O-GlcNAc transferase invokes nucleotide sugar pyrophosphate participation in catalysis
Protein O-GlcNAcylation is an essential post-translational modification on hundreds of intracellular proteins in metazoa, catalyzed by O -linked β- N -ac...
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Integrated LC/MS and GC/MS Metabolomics Data for the Evaluation of Protection Function of Fructus Ligustri Lucidi on Mouse Liver
A comprehensive metabolomic strategy, integrating GC/MS and LC/MS data, had been developed to study the protection function of herbal medicine, Fructus...
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Ionic Liquids as Green Solvents for Glycosylation Reactions
This chapter deals with how we took advantages of unique properties of ionic liquids in glycosylation reactions, such as their tunability, basicity...
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Selective anomeric deacetylation using zinc acetate as catalyst
An alternative method has been developed for the anomeric deacetylation of fully acetylated carbohydrate derivatives using zinc acetate dihydrate as...
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Prospects of reusable endogenous hydrolyzing enzymes in bioethanol production by simultaneous saccharification and fermentation
This study was conducted to evaluate the presence, origination and classification of various hydrolyzing enzymes from malt and their specified...
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Enzyme-assisted food processing
Enzymes, as biological catalysts, have been used extensively as processing aids in the food industry for the past several decades. They help to...
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A neutral diphosphate mimic crosslinks the active site of human O-GlcNAc transferase
Glycosyltransferases (Gtfs) catalyze the formation of a diverse array of glycoconjugates. Small-molecule inhibitors to manipulate Gtf activity in...
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Using simple donors to drive the equilibria of glycosyltransferase-catalyzed reactions
We report that simple glycoside donors can drastically shift the equilibria of glycosyltransferase-catalyzed reactions, transforming NDP-sugar...
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Calculation of Hydrodynamic Properties for G-Quadruplex Nucleic Acid Structures from in silico Bead Models
Nucleic acids enriched in guanine bases can adopt unique quadruple helical tertiary structures known as G-quadruplexes. G-quadruplexes have emerged...
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Chemical Synthesis of Lipid A and Analogues
Chemical syntheses of lipid A and its analogues have made substantial contributions to our current understanding of the endotoxic active structures...
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Catalytic Oxidation and Deoxygenation of Renewables with Rhenium Complexes
Transformation of renewables has received major research interest in recent years, opening up completely new research areas, in particular in the...
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Biocatalytic Applications
Of all the types of enzyme-catalyzed reactions, hydrolytic transformations involving amide and ester bonds are the easiest to perform using...
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Organic Phosphorus-Selenium Chemistry
The reactivity and application of typical organic P-Se containing compounds, namely, selenotriphosphines SePR3, secondary selenophosphines SePHR2,...