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Insights into the release mechanisms of antioxidants from nanoemulsion droplets
The therapeutic effects of antioxidant-loaded nanoemulsion can be often optimized by controlling the release rate in human body. Release kinetic...
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Detection of SARS-CoV-2 receptor binding domain using fluorescence probe and DNA flowers enabled by rolling circle amplification
Using rolling circle amplification (RCA) and two different ways of signal readout, we developed analytical methods to detect the receptor-binding...
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Organoboron chemistry towards controlled and precise polymer synthesis
Organoboron reagents have garnered considerable attention due to their distinct properties. In recent years, boronic acids and boronate esters have...
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Revolutionizing lymph node metastasis imaging: the role of drug delivery systems and future perspectives
The deployment of imaging examinations has evolved into a robust approach for the diagnosis of lymph node metastasis (LNM). The advancement of...
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Microencapsulation Methods for Food Antioxidants
Antioxidants are important constituents of foods due to their potential to delay or inhibit oxidation, extend the shelf life, and protect the... -
Nano-immunotherapy: overcoming delivery challenge of immune checkpoint therapy
Immune checkpoint (ICP) molecules expressed on tumor cells can suppress immune responses against tumors. ICP therapy promotes anti-tumor immune...
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Targeted Delivery of Probiotics: Perspectives on Research and Commercialization
Considering the significance of the gut microbiota on human health, there has been ever-growing research and commercial interest in various aspects...
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Spray-dried cellulose nanofibrils microparticles as a vehicle for enhanced efficiency fertilizers
AbstractThis paper reports the role of cellulose and cellulose nanofibrils (CNFs) as a material to encapsulate nutrients applied in agriculture....
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Encapsulation of polyethylene glycol in cellulose-based porous capsules for latent heat storage and light-to-thermal conversion
Phase change materials are potential candidates for the application of latent heat storage. Herein, we fabricated porous capsules as shape-stable...
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Nanomaterials for Therapeutic Nucleic Acid Delivery
Nucleic acids and their chemically modified derivatives have gradually become an important class of therapeutic agents. Several nucleic acid-based... -
Morphology Engineering for Covalent Organic Frameworks (COFs) by Surfactant Mediation and Acid Adjustment
Two-dimensional covalent organic frameworks (COFs) with specific morphologies including nanofibers and nanoplates are highly desired in both...
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Dendritic cell hybrid nanovaccine for mild heat inspired cancer immunotherapy
Cancer therapeutic vaccine can induce antigen-specific immune response, which has shown great potential in cancer immunotherapy. As the key factor of...
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Encapsulation of curcumin in gliadin-pectin in a core–shell nanostructure for efficient delivery of curcumin to cancer cells in vitro
Curcumin, as a bioactive compound, has shown promising activity in cancer treatment, although having poor water solubility and bioavailability. Here,...
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Hexnut[12]arene and its derivatives: Synthesis, host-guest properties, and application as nonporous adaptive crystals
Hexnut[12]arene (HN[12]) and its derivatives, a new class of sixfold macrocyclic arenes, were designed and synthesized in reasonable yield by a...
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Inclusion complex of emodin and glycyrrhetinic acid-conjugated-β-cyclodextrin to target liver cells: synthesis, characterization, and bioactivity in vitro and in vivo
The objective of this study is to prepare a novel delivery vector, glycyrrhetinic acid -conjugated-β-cyclodextrin (GA-CD) for liver targeting, and...
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Janus particles by simplified RAFT-based emulsion polymerization process for polymer coating
We describe a simplified method to synthesize film forming polymer Janus particles by phase separation during RAFT-based free radical emulsion...
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Hydrogels for Biomedicine Based on Semi-Interpenetrating Polymeric Networks of Collagen/Guar Gum: Applications in Biomedical Field and Biocompatibility
Determining the controlled release capacity of drugs with therapeutic interest as well as the biocompatibility of hydrogels based on natural and...
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Encapsulation of ultrafine Pd nanoparticles within the shallow layers of UiO-67 for highly efficient hydrogenation reactions
Metal-organic frameworks (MOFs) have been used to encapsulate active metal nanoparticles (MNPs) to fabricate MNPs@MOFs composites with high catalytic...
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Laboratory Scale Production of Complex Proteins Using Charge Complimentary Nanoenvironments
Protein refolding is a crucial procedure in bacterial recombinant expression. Aggregation and misfolding are the two challenges that can affect the... -
Lysosomal escaped protein nanocarriers for nuclear-targeted siRNA delivery
In the process of drug carrier design, lysosome degradation in cells is often neglected, which makes a considerable number of drugs not play a role....